Skin science article
Abib Collagen Eye Patch Jericho Rose Jelly Versus MEDI-PEEL Hyaluron Dark Benone Peptide 9 Ampoule Eye Patch
Abib Collagen Eye Patch Jericho Rose Jelly Versus MEDI-PEEL Hyaluron Dark Benone Peptide 9 Ampoule Eye Patch This anti-aging eye mask is formulated around Niacinamide and Collagen Extract to soften the look of wrinkles and hydrate skin. This anti-aging eye mas
Abib Collagen Eye Patch Jericho Rose Jelly Versus MEDI-PEEL Hyaluron Dark Benone Peptide 9 Ampoule Eye Patch
This anti-aging eye mask is formulated around Niacinamide and Collagen Extract to soften the look of wrinkles and hydrate skin.
This anti-aging eye mask is formulated around Sodium Hyaluronate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Niacinamide
Chondrus Crispus Powder
Collagen Extract
1,2-Hexanediol
Betaine
Ceratonia Siliqua Gum
Cyamopsis Tetragonoloba Gum
Hydroxyacetophenone
Chondrus Crispus
Calcium Chloride
Allantoin
Butyrospermum Parkii Butter
Propanediol
Polyglyceryl-10 Laurate
Polyglyceryl-3 Methylglucose Distearate
Potassium Chloride
Anastatica Hierochuntica Extract
Cellulose Gum
Ricinus Communis Seed Oil
Trehalose
Sucrose
Caprylyl Glycol
Adenosine
Ethylhexylglycerin
Dipotassium Glycyrrhizate
Sodium Hyaluronate
Caffeine
Panthenol
Ceramide NP
Palmitoyl Tripeptide-5
Water, Glycerin, Niacinamide, Chondrus Crispus Powder, Collagen Extract, 1,2-Hexanediol, Betaine, Ceratonia Siliqua Gum, Cyamopsis Tetragonoloba Gum, Hydroxyacetophenone, Chondrus Crispus, Calcium Chloride, Allantoin, Butyrospermum Parkii Butter, Propanediol, Polyglyceryl-10 Laurate, Polyglyceryl-3 Methylglucose Distearate, Potassium Chloride, Anastatica Hierochuntica Extract, Cellulose Gum, Ricinus Communis Seed Oil, Trehalose, Sucrose, Caprylyl Glycol, Adenosine, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Caffeine, Panthenol, Ceramide NP, Palmitoyl Tripeptide-5
Carrageenan
Butylene Glycol
Hydrolyzed Collagen
Hydrolyzed Hyaluronic Acid
Sodium Acetylated Hyaluronate
Hydroxypropyltrimonium Hyaluronate
Potassium Hyaluronate
Sodium Hyaluronate Crosspolymer
Hyaluronic Acid
Pearl Extract
Polysorbate 80
Tocopheryl Acetate
Ubiquinone
Acetyl Hexapeptide-8
Copper Tripeptide-1
Oligopeptide-29
Oligopeptide-32
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Glyceryl Polymethacrylate
Propylene Glycol
Palmitoyl Oligopeptide
Pentylene Glycol
Cocos Nucifera Fruit Extract
Pinus Sylvestris Leaf Extract
Calcium Lactate
Caprylic/Capric Triglyceride
Sorbitan Caprylate
PEG-60 Hydrogenated Castor Oil
Diamond Powder
Titanium Dioxide
Oleth-10
Triethoxycaprylylsilane
Polysorbate 60
Simethicone
Methyl Methacrylate Crosspolymer
Aluminum Hydroxide
Synthetic Fluorphlogopite
Arginine
Disodium EDTA
Chlorphenesin
Ethyl Hexanediol
Parfum
Water, Glycerin, Carrageenan, Butylene Glycol, Hydrolyzed Collagen, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Pearl Extract, Polysorbate 80, Tocopheryl Acetate, Ubiquinone, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Glyceryl Polymethacrylate, Propylene Glycol, Palmitoyl Oligopeptide, Palmitoyl Tripeptide-5, Propanediol, Pentylene Glycol, Cocos Nucifera Fruit Extract, Pinus Sylvestris Leaf Extract, Ricinus Communis Seed Oil, Butyrospermum Parkii Butter, Betaine, Allantoin, Dipotassium Glycyrrhizate, Ceratonia Siliqua Gum, Sucrose, Cyamopsis Tetragonoloba Gum, Cellulose Gum, Potassium Chloride, Calcium Chloride, Calcium Lactate, Caprylic/Capric Triglyceride, Sorbitan Caprylate, PEG-60 Hydrogenated Castor Oil, Diamond Powder, Titanium Dioxide, Oleth-10, Triethoxycaprylylsilane, Polysorbate 60, Simethicone, Methyl Methacrylate Crosspolymer, Aluminum Hydroxide, Synthetic Fluorphlogopite, Arginine, Disodium EDTA, Chlorphenesin, Ethyl Hexanediol, 1,2-Hexanediol, Ethylhexylglycerin, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
Calcium chloride is a white, odorless, crystalline solid. It is an astringent and can be used to change the viscosity of products.
This ingredient is highly soluble in water, acetic acid, and ethanol.
There are many forms of this ingredient, including monohydrate, dihydrate, tetrahydrate, and hexahydrate.
Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Ceratonia Siliqua Gum is extracted from the seeds of the carob tree. You might know this ingredient as Carob Gum or Locust Bean Gum. It is used to stabilize other ingredients and improve the texture of products.
Carob gum is made up of long-chain polysaccharides. This makes it a natural thickener.
Yes! This ingredient comes from the seeds of a tree. The name 'Locust Bean Gum' can be misleading.
Guar gum is made from the guar bean, a plant native to India. It is considered a form of polysaccharide and naturally contains sugar.
This ingredient is often used to thicken a product or create a gel-like consistency.
It also has emulsion properties to help keep ingredients together.
Dipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front: Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
We don't have a description for Potassium Chloride yet.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
This ingredient is also known as castor oil. It is a skin conditioning ingredient.
The star component of castor oil is ricinoleic acid, an unusual fatty acid that makes up ~80-92% of its composition.
In skincare, it is an emollient that dries down to a solid film with water-binding properties. This helps keep skin hydrated and helps reduce transepidermal water loss (TEWL).
A 2026 dermatology review pulls together its broader uses:
Human clinical testing found this ingredient to be non-irritating and non-sensitizing.
Because castor oil contains fatty acids in the C11-24 range, this ingredient may not be fungal acne safe.
At this time, the literature does not support castor oil in regrowing hair. A 2022 systematic review found no strong evidence that it supports hair growth and only weak evidence that it improves hair shine.
Castor oil itself carries "perfuming" and "masking" function tags according to the official CosIng database. This is because of its mild odor and odor-dampening properties.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sucrose is a natural sugar found in fruits, vegetables, and nuts. It is the main constituent of white sugar.
In skincare, sucrose is a humectant and can be a mild exfoliant.
Sucrose is hydrophilic, meaning it attracts water. This makes it an effective humectant and helps hydrate the skin.
Studies show sugars may worsen acne-prone skin due to it disrupting the skin's natural biome. We recommend speaking with a professional if you have any concerns.
In some products such as body scrubs, sucrose is used as an gentle exfoliant.
The term 'sucrose' comes from the french word for sugar, 'sucre'.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!