Skin science article
Abib Glutathiosome Dark Spot Serum Vita Drop Versus Biodance Pore Perfecting Collagen Peptide Serum
Abib Glutathiosome Dark Spot Serum Vita Drop Versus Biodance Pore Perfecting Collagen Peptide Serum This brightening serum is formulated around Niacinamide and Glutathione to fade the look of dark spots and brighten dull-looking skin. This pore-care serum is f
Abib Glutathiosome Dark Spot Serum Vita Drop Versus Biodance Pore Perfecting Collagen Peptide Serum
This brightening serum is formulated around Niacinamide and Glutathione to fade the look of dark spots and brighten dull-looking skin.
This pore-care serum is formulated around Collagen Water and Niacinamide to refine the look of pores and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Butylene Glycol
Niacinamide
1,2-Hexanediol
Zea Mays Starch
Chondrus Crispus Extract
Chlorella Vulgaris Extract
Saccharum Officinarum Extract
Centella Asiatica Leaf Extract
Chitosan
Malus Domestica Fruit Cell Culture Extract
Polyacrylate Crosspolymer-6
Betaine
Glucose
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tromethamine
Acetyl Glucosamine
Fructooligosaccharides
Fructose
Glycerin
Pentylene Glycol
Ethylhexylglycerin
Allantoin
Dipropylene Glycol
Adenosine
Glutathione
Madecassoside
Hydroxypropyl Methylcellulose
Hydrogenated Lecithin
Beta-Glucan
Cholesterol
Asiaticoside
Ascorbic Acid
3-O-Ethyl Ascorbic Acid
Ascorbyl Glucoside
Ceramide NP
Tocopherol
Ferulic Acid
Lactic Acid
Disodium EDTA
Carbomer
CI 77491
Water, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Zea Mays Starch, Chondrus Crispus Extract, Chlorella Vulgaris Extract, Saccharum Officinarum Extract, Centella Asiatica Leaf Extract, Chitosan, Malus Domestica Fruit Cell Culture Extract, Polyacrylate Crosspolymer-6, Betaine, Glucose, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Acetyl Glucosamine, Fructooligosaccharides, Fructose, Glycerin, Pentylene Glycol, Ethylhexylglycerin, Allantoin, Dipropylene Glycol, Adenosine, Glutathione, Madecassoside, Hydroxypropyl Methylcellulose, Hydrogenated Lecithin, Beta-Glucan, Cholesterol, Asiaticoside, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Ascorbyl Glucoside, Ceramide NP, Tocopherol, Ferulic Acid, Lactic Acid, Disodium EDTA, Carbomer, CI 77491
Collagen Water
Tripropylene Glycol
Trehalose
Sodium Polyacryloyldimethyl Taurate
Polyglyceryl-10 Laurate
Sodium Polyacrylate
Hydrolyzed Hyaluronic Acid
Xanthan Gum
Polyquaternium-51
Glyceryl Acrylate/Acrylic Acid Copolymer
Caprylyl Glycol
Pvm/Ma Copolymer
Cyanocobalamin
Coptis Japonica Root Extract
Sodium Hyaluronate
Hydroxypropyltrimonium Hyaluronate
Propanediol
Saccharide Isomerate
Sodium Acetylated Hyaluronate
Collagen Extract
Hyaluronic Acid
Hydrolyzed Sodium Hyaluronate
Sodium Hyaluronate Crosspolymer
Alginic Acid
Silanetriol
Potassium Hyaluronate
Hydrolyzed Elastin
Elastin
Soluble Elastin
Tripeptide-1
Acetyl Hexapeptide-8
Copper Tripeptide-1
Palmitoyl Tripeptide-5
Sh-Oligopeptide-1
Pentapeptide-4
Palmitoyl Tripeptide-38
Hexapeptide-9
Hexapeptide-12
Palmitoyl Pentapeptide-4
Collagen Water, Water, Glycerin, Tripropylene Glycol, 1,2-Hexanediol, Niacinamide, Trehalose, Sodium Polyacryloyldimethyl Taurate, Butylene Glycol, Allantoin, Polyglyceryl-10 Laurate, Sodium Polyacrylate, Ethylhexylglycerin, Hydrolyzed Hyaluronic Acid, Adenosine, Xanthan Gum, Polyquaternium-51, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Caprylyl Glycol, Pvm/Ma Copolymer, Cyanocobalamin, Coptis Japonica Root Extract, Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Tocopherol, Propanediol, Saccharide Isomerate, Sodium Acetylated Hyaluronate, Collagen Extract, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Alginic Acid, Silanetriol, Potassium Hyaluronate, Hydrolyzed Elastin, Elastin, Soluble Elastin, Tripeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-5, Sh-Oligopeptide-1, Pentapeptide-4, Palmitoyl Tripeptide-38, Hexapeptide-9, Hexapeptide-12, Palmitoyl Pentapeptide-4
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!