Skin science article
Abib PDRN Retinal Eye Patch Glow Jelly Versus Biodance Collagen Peptide Eye Patches
Abib PDRN Retinal Eye Patch Glow Jelly Versus Biodance Collagen Peptide Eye Patches This anti-aging eye mask is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and brighten dull-looking skin. This anti-aging eye mask is formulated a
Abib PDRN Retinal Eye Patch Glow Jelly Versus Biodance Collagen Peptide Eye Patches
This anti-aging eye mask is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and brighten dull-looking skin.
This anti-aging eye mask is formulated around Collagen Water and Niacinamide to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Niacinamide
Butylene Glycol
Carrageenan
Glucomannan
1,2-Hexanediol
Ceratonia Siliqua Gum
Hydroxyacetophenone
Gellan Gum
Allantoin
Caprylyl Glycol
Sucrose
Cyamopsis Tetragonoloba Gum
Caffeine
Dipotassium Glycyrrhizate
Synthetic Fluorphlogopite
Adenosine
Calcium Chloride
Propanediol
Polyglyceryl-10 Laurate
Ethylhexylglycerin
Titanium Dioxide
Panthenol
Sodium Hyaluronate
Collagen
Squalane
Arginine
Hydrogenated Lecithin
CI 77491
Sodium DNA
Centella Asiatica Extract
Ginkgo Biloba Leaf Extract
Phyllostachys Pubescens Shoot Bark Extract
Glycine Soja Sterols
Polymethylsilsesquioxane
Silica
Polyglyceryl-10 Oleate
Retinal
Water, Glycerin, Niacinamide, Butylene Glycol, Carrageenan, Glucomannan, 1,2-Hexanediol, Ceratonia Siliqua Gum, Hydroxyacetophenone, Gellan Gum, Allantoin, Caprylyl Glycol, Sucrose, Cyamopsis Tetragonoloba Gum, Caffeine, Dipotassium Glycyrrhizate, Synthetic Fluorphlogopite, Adenosine, Calcium Chloride, Propanediol, Polyglyceryl-10 Laurate, Ethylhexylglycerin, Titanium Dioxide, Panthenol, Sodium Hyaluronate, Collagen, Squalane, Arginine, Hydrogenated Lecithin, CI 77491, Sodium DNA, Centella Asiatica Extract, Ginkgo Biloba Leaf Extract, Phyllostachys Pubescens Shoot Bark Extract, Glycine Soja Sterols, Polymethylsilsesquioxane, Silica, Polyglyceryl-10 Oleate, Retinal
Collagen Water
Chondrus Crispus Powder
Betaine
Chondrus Crispus
Polyglyceryl-3 Methylglucose Distearate
Potassium Chloride
Trehalose
Butyrospermum Parkii Butter
Calcium Aluminum Borosilicate
Cellulose Gum
CI 77891
Hydrolyzed Hyaluronic Acid
Tin Oxide
Lactobacillus Ferment Lysate
Hydrolyzed Collagen
Tocopherol
Collagen Extract
Elastin
Glycosaminoglycans
Acetyl Hexapeptide-8
Ascorbic Acid Polypeptide
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-22
Sh-Polypeptide-3
Acetyl Octapeptide-3
Acetyl Tetrapeptide-2
Acetyl Tetrapeptide-3
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-9
Carnosine
Copper Tripeptide-1
Nonapeptide-1
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-5
Water, Glycerin, Collagen Water, Niacinamide, Chondrus Crispus Powder, Butylene Glycol, 1,2-Hexanediol, Ceratonia Siliqua Gum, Betaine, Hydroxyacetophenone, Chondrus Crispus, Cyamopsis Tetragonoloba Gum, Calcium Chloride, Allantoin, Polyglyceryl-3 Methylglucose Distearate, Potassium Chloride, Glucomannan, Polyglyceryl-10 Laurate, Propanediol, Trehalose, Butyrospermum Parkii Butter, Calcium Aluminum Borosilicate, Sucrose, Cellulose Gum, Adenosine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, CI 77891, Caffeine, CI 77491, Hydrolyzed Hyaluronic Acid, Tin Oxide, Lactobacillus Ferment Lysate, Hydrolyzed Collagen, Tocopherol, Collagen Extract, Elastin, Glycosaminoglycans, Sodium Hyaluronate, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Sh-Polypeptide-3, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Carnosine, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Calcium chloride is a white, odorless, crystalline solid. It is an astringent and can be used to change the viscosity of products.
This ingredient is highly soluble in water, acetic acid, and ethanol.
There are many forms of this ingredient, including monohydrate, dihydrate, tetrahydrate, and hexahydrate.
Ceratonia Siliqua Gum is extracted from the seeds of the carob tree. You might know this ingredient as Carob Gum or Locust Bean Gum. It is used to stabilize other ingredients and improve the texture of products.
Carob gum is made up of long-chain polysaccharides. This makes it a natural thickener.
Yes! This ingredient comes from the seeds of a tree. The name 'Locust Bean Gum' can be misleading.
Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Guar gum is made from the guar bean, a plant native to India. It is considered a form of polysaccharide and naturally contains sugar.
This ingredient is often used to thicken a product or create a gel-like consistency.
It also has emulsion properties to help keep ingredients together.
Dipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glucomannan is a fiber created from the Konjac plant. It is an emulsifier and thickener.
The high polysaccharide content makes it great at adjusting the texture of products. (Kind of like starch).
Polysaccharides also help our skin stay hydrated.
This ingredient is water-soluble.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier.
It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.
On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).
Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.
This ingredient is an ester of lauric acid and Polyglycerin-10.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sucrose is a natural sugar found in fruits, vegetables, and nuts. It is the main constituent of white sugar.
In skincare, sucrose is a humectant and can be a mild exfoliant.
Sucrose is hydrophilic, meaning it attracts water. This makes it an effective humectant and helps hydrate the skin.
Studies show sugars may worsen acne-prone skin due to it disrupting the skin's natural biome. We recommend speaking with a professional if you have any concerns.
In some products such as body scrubs, sucrose is used as an gentle exfoliant.
The term 'sucrose' comes from the french word for sugar, 'sucre'.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!