Skin science article
Acure Radically Rejuvenating Dual Phase Bakuchiol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment
Acure Radically Rejuvenating Dual Phase Bakuchiol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment This anti-aging serum is formulated around Tocopherol and Ascorbyl Glucoside to soften the look of wrinkles and refine skin texture. Th
Acure Radically Rejuvenating Dual Phase Bakuchiol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment
This anti-aging serum is formulated around Tocopherol and Ascorbyl Glucoside to soften the look of wrinkles and refine skin texture.
This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Propanediol
Glycerin
Tocopherol
Ascorbyl Glucoside
Bakuchiol
Solanum Melongena Fruit Extract
Curcuma Longa Root Extract
Ocimum Basilicum Flower/Leaf Extract
Coccinia Indica Fruit Extract
Aloe Barbadensis Flower Extract
Melia Azadirachta Flower Extract
Melia Azadirachta Leaf Extract
Ocimum Sanctum Leaf Extract
Marrubium Vulgare Extract
Corallina Officinalis Extract
Simmondsia Chinensis Seed Oil
Xanthan Gum
Sodium Levulinate
Potassium Sorbate
Sodium Benzoate
Citric Acid
Water, Caprylic/Capric Triglyceride, Propanediol, Glycerin, Tocopherol, Ascorbyl Glucoside, Bakuchiol, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Ocimum Sanctum Leaf Extract, Marrubium Vulgare Extract, Corallina Officinalis Extract, Simmondsia Chinensis Seed Oil, Xanthan Gum, Sodium Levulinate, Potassium Sorbate, Sodium Benzoate, Citric Acid
Dimethicone
Pentaerythrityl Tetraisostearate
Isononyl Isononanoate
Butylene Glycol
Arachidyl Alcohol
Glyceryl Polymethacrylate
Dimethicone Crosspolymer
Behenyl Alcohol
PEG-75 Shea Butter Glycerides
Glyceryl Stearate
C12-15 Alkyl Benzoate
Polysorbate 20
Tetrahexyldecyl Ascorbate
Retinol
Ceramide Ng
Palmitoyl Tetrapeptide-7
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Dipotassium Glycyrrhizate
Glycyrrhiza Glabra Root Extract
Avena Sativa Kernel Extract
Arctium Lappa Root Extract
Salix Alba Bark Extract
Glycine Soja Sterols
Lecithin
Allantoin
Tocopheryl Acetate
Hydrolyzed Soy Protein
Palmitoyl Tripeptide-1
Sodium Hydroxide
Tribehenin
Caprylyl Glycol
Dipeptide-2
Polygonum Cuspidatum Root Extract
PEG-10 Phytosterol
PEG-8
Magnesium Aluminum Silicate
Arachidyl Glucoside
Chrysin
Pentylene Glycol
Sodium Acrylates Copolymer
Steareth-20
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Cetearyl Alcohol
Coco-Glucoside
Hesperidin Methyl Chalcone
N-Hydroxysuccinimide
Disodium EDTA
Phenoxyethanol
Benzoic Acid
Ethylhexylglycerin
Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties.
You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to:
1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do
Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).
The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.
Systematic reviews also back this up:
Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.
The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.
This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!