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Acure Radically Rejuvenating Dual Phase Bakuchiol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

Acure Radically Rejuvenating Dual Phase Bakuchiol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment This anti-aging serum is formulated around Tocopherol and Ascorbyl Glucoside to soften the look of wrinkles and refine skin texture. Th

Acure Radically Rejuvenating Dual Phase Bakuchiol Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

This anti-aging serum is formulated around Tocopherol and Ascorbyl Glucoside to soften the look of wrinkles and refine skin texture.

This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Propanediol

Glycerin

Tocopherol

Ascorbyl Glucoside

Bakuchiol

Solanum Melongena Fruit Extract

Curcuma Longa Root Extract

Ocimum Basilicum Flower/Leaf Extract

Coccinia Indica Fruit Extract

Aloe Barbadensis Flower Extract

Melia Azadirachta Flower Extract

Melia Azadirachta Leaf Extract

Ocimum Sanctum Leaf Extract

Marrubium Vulgare Extract

Corallina Officinalis Extract

Simmondsia Chinensis Seed Oil

Xanthan Gum

Sodium Levulinate

Potassium Sorbate

Sodium Benzoate

Citric Acid

Water, Caprylic/Capric Triglyceride, Propanediol, Glycerin, Tocopherol, Ascorbyl Glucoside, Bakuchiol, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Ocimum Sanctum Leaf Extract, Marrubium Vulgare Extract, Corallina Officinalis Extract, Simmondsia Chinensis Seed Oil, Xanthan Gum, Sodium Levulinate, Potassium Sorbate, Sodium Benzoate, Citric Acid

Dimethicone

Pentaerythrityl Tetraisostearate

Isononyl Isononanoate

Butylene Glycol

Arachidyl Alcohol

Glyceryl Polymethacrylate

Dimethicone Crosspolymer

Behenyl Alcohol

PEG-75 Shea Butter Glycerides

Glyceryl Stearate

C12-15 Alkyl Benzoate

Polysorbate 20

Tetrahexyldecyl Ascorbate

Retinol

Ceramide Ng

Palmitoyl Tetrapeptide-7

Palmitoyl Hexapeptide-12

Sodium Hyaluronate

Dipotassium Glycyrrhizate

Glycyrrhiza Glabra Root Extract

Avena Sativa Kernel Extract

Arctium Lappa Root Extract

Salix Alba Bark Extract

Glycine Soja Sterols

Lecithin

Allantoin

Tocopheryl Acetate

Hydrolyzed Soy Protein

Palmitoyl Tripeptide-1

Sodium Hydroxide

Tribehenin

Caprylyl Glycol

Dipeptide-2

Polygonum Cuspidatum Root Extract

PEG-10 Phytosterol

PEG-8

Magnesium Aluminum Silicate

Arachidyl Glucoside

Chrysin

Pentylene Glycol

Sodium Acrylates Copolymer

Steareth-20

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetearyl Alcohol

Coco-Glucoside

Hesperidin Methyl Chalcone

N-Hydroxysuccinimide

Disodium EDTA

Phenoxyethanol

Benzoic Acid

Ethylhexylglycerin

Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties.

You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to:

1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do

Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).

The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.

Systematic reviews also back this up:

Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.

The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.

This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
  4. 04You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
  5. 05The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
  6. 06Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
  7. 07Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
  8. 08Its main roles are:
  9. 09Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
  10. 10The FDA allows products labeled "alcohol-free" to have fatty alcohols.
  11. 11This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
  12. 12Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  13. 13What it does:
  14. 14Dimethicone comes in different viscosities:
  15. 15Depending on the viscosity, dimethicone has different properties.
  16. 16Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  17. 17This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  18. 18Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  19. 19Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  20. 20This ingredient mainly works behind the scenes and helps with:
Source · skinsort.com
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Product index

Related product references

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Comparison edit

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