Skin science article
Aestura Atobarrier 365 Cream Versus Drunk Elephant Protini Polypeptide Cream
Aestura Atobarrier 365 Cream Versus Drunk Elephant Protini Polypeptide Cream This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin. This anti-aging moisturizer is form
Aestura Atobarrier 365 Cream Versus Drunk Elephant Protini Polypeptide Cream
This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin.
This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Glycerin
Butylene Glycol Dicaprylate/Dicaprate
Cetyl Ethylhexanoate
Squalane
Pentaerythrityl Tetraisostearate
Dicaprylyl Carbonate
Behenyl Alcohol
Dimethicone
Hydroxypropyl Bispalmitamide Mea
Stearic Acid
Betaine
Mannitol
C14-22 Alcohols
Palmitic Acid
Hydroxypropyl Bislauramide Mea
Arachidyl Alcohol
Cholesterol
Polyacrylate-13
C12-20 Alkyl Glucoside
Allantoin
Arachidyl Glucoside
Niacinamide
Ceramide NP
Glyceryl Caprylate
Ethylhexylglycerin
Hydrogenated Polyisobutene
Carbomer
Tromethamine
Dimethiconol
Polyglyceryl-10 Laurate
Hydrogenated Lecithin
Ethylhexyl Palmitate
Acrylates/Ammonium Methacrylate Copolymer
Sorbitan Isostearate
Silica
Phytosphingosine
Sphingolipids
Arachidic Acid
Tocopherol
Oleic Acid
Water, Butylene Glycol, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Cetyl Ethylhexanoate, Squalane, Pentaerythrityl Tetraisostearate, Dicaprylyl Carbonate, Behenyl Alcohol, Dimethicone, Hydroxypropyl Bispalmitamide Mea, Stearic Acid, Betaine, Mannitol, C14-22 Alcohols, Palmitic Acid, Hydroxypropyl Bislauramide Mea, Arachidyl Alcohol, Cholesterol, Polyacrylate-13, C12-20 Alkyl Glucoside, Allantoin, Arachidyl Glucoside, Niacinamide, Ceramide NP, Glyceryl Caprylate, Ethylhexylglycerin, Hydrogenated Polyisobutene, Carbomer, Tromethamine, Dimethiconol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Ethylhexyl Palmitate, Acrylates/Ammonium Methacrylate Copolymer, Sorbitan Isostearate, Silica, Phytosphingosine, Sphingolipids, Arachidic Acid, Tocopherol, Oleic Acid
Cetearyl Alcohol
Cetearyl Olivate
Sorbitan Olivate
Sclerocarya Birrea Seed Oil
Bacillus/Folic Acid Ferment Filtrate Extract
Nymphaea Alba Root Extract
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Alanine
Arginine
Glycine
Histidine
Isoleucine
Phenylalanine
Proline
Serine
Threonine
Valine
Acetyl Glutamine
Coconut Alkanes
Coco-Caprylate/Caprate
Sodium Hyaluronate
Aspartic Acid
Linoleic Acid
Linolenic Acid
Lecithin
Polyvinyl Alcohol
Sodium Lactate
Sodium PCA
PCA
Polysorbate 20
Polysorbate 60
Lactic Acid/Glycolic Acid Copolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Xanthan Gum
Isomalt
1,2-Hexanediol
Caprylyl Glycol
Chlorphenesin
Phenoxyethanol
Sodium Benzoate
Phenylpropanol
Symphytum Officinale Callus Culture Extract
Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals.
As an emollient, Dicaprylyl Carbonate creates a film on the skin. This film traps moisture in, keeping your skin soft and hydrated.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.
Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.
As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.
Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.
Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.
Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).
Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.
As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.
In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.
Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!