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Skin science article

Aestura Atobarrier 365 Cream Versus First Aid Beauty Ultra Repair Barriair cream

Aestura Atobarrier 365 Cream Versus First Aid Beauty Ultra Repair Barriair cream This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer

Aestura Atobarrier 365 Cream Versus First Aid Beauty Ultra Repair Barriair cream

This barrier-repair moisturizer is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Ceramide Ng and Linoleic Acid to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Butylene Glycol Dicaprylate/Dicaprate

Cetyl Ethylhexanoate

Squalane

Pentaerythrityl Tetraisostearate

Dicaprylyl Carbonate

Behenyl Alcohol

Dimethicone

Hydroxypropyl Bispalmitamide Mea

Stearic Acid

Betaine

Mannitol

C14-22 Alcohols

Palmitic Acid

Hydroxypropyl Bislauramide Mea

Arachidyl Alcohol

Cholesterol

Polyacrylate-13

C12-20 Alkyl Glucoside

Allantoin

Arachidyl Glucoside

Niacinamide

Ceramide NP

Glyceryl Caprylate

Ethylhexylglycerin

Hydrogenated Polyisobutene

Carbomer

Tromethamine

Dimethiconol

Polyglyceryl-10 Laurate

Hydrogenated Lecithin

Ethylhexyl Palmitate

Acrylates/Ammonium Methacrylate Copolymer

Sorbitan Isostearate

Silica

Phytosphingosine

Sphingolipids

Arachidic Acid

Tocopherol

Oleic Acid

Water, Butylene Glycol, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Cetyl Ethylhexanoate, Squalane, Pentaerythrityl Tetraisostearate, Dicaprylyl Carbonate, Behenyl Alcohol, Dimethicone, Hydroxypropyl Bispalmitamide Mea, Stearic Acid, Betaine, Mannitol, C14-22 Alcohols, Palmitic Acid, Hydroxypropyl Bislauramide Mea, Arachidyl Alcohol, Cholesterol, Polyacrylate-13, C12-20 Alkyl Glucoside, Allantoin, Arachidyl Glucoside, Niacinamide, Ceramide NP, Glyceryl Caprylate, Ethylhexylglycerin, Hydrogenated Polyisobutene, Carbomer, Tromethamine, Dimethiconol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Ethylhexyl Palmitate, Acrylates/Ammonium Methacrylate Copolymer, Sorbitan Isostearate, Silica, Phytosphingosine, Sphingolipids, Arachidic Acid, Tocopherol, Oleic Acid

Propanediol

Caprylic/Capric Triglyceride

Polymethyl Methacrylate

Oxygen

Ceramide Ng

Linoleic Acid

Linolenic Acid

Glycyrrhiza Glabra Root Extract

Chrysanthemum Parthenium Extract

Camellia Sinensis Leaf Extract

Sodium Hyaluronate

Colloidal Oatmeal

Caprylyl Glycol

Hydrolyzed Yeast Extract

Cetyl Hydroxyethylcellulose

Polyglucuronic Acid

Cetyl Alcohol

Sodium Polyacrylate Starch

Dipropylene Glycol

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Glyceryl Stearate

Sodium Polyacrylate

Polypropylene

Polysorbate 80

Steareth-30

Lecithin

Leuconostoc/Radish Root Ferment Filtrate

Phenoxyethanol

Perfluorohexane

Chlorphenesin

Perfluoromethylcyclopentane

Sodium Benzoate

Potassium Sorbate

Water, Glycerin, Propanediol, Cetyl Ethylhexanoate, Caprylic/Capric Triglyceride, Polymethyl Methacrylate, Oxygen, Ceramide Ng, Linoleic Acid, Linolenic Acid, Glycyrrhiza Glabra Root Extract, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Sodium Hyaluronate, Tocopherol, Colloidal Oatmeal, Caprylyl Glycol, Hydrolyzed Yeast Extract, Cetyl Hydroxyethylcellulose, Cholesterol, Polyglucuronic Acid, Cetyl Alcohol, Sodium Polyacrylate Starch, Stearic Acid, Dipropylene Glycol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate, Sodium Polyacrylate, Polypropylene, Polysorbate 80, Steareth-30, Lecithin, Ethylhexylglycerin, Leuconostoc/Radish Root Ferment Filtrate, Phenoxyethanol, Perfluorohexane, Chlorphenesin, Perfluoromethylcyclopentane, Sodium Benzoate, Potassium Sorbate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Cetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.

Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.

It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
  4. 04Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
  5. 05Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
  6. 06It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
  7. 07Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
  8. 08This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
  9. 09Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
  10. 10Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
  11. 11Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
  12. 12Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
  13. 13It plays several roles in a formula:
  14. 14Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
  15. 15Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
  16. 16However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
  17. 17Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
  18. 18Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
  19. 19Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
  20. 20This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
Source · skinsort.com
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Comparison edit

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