Skin science article
Aestura Atobarrier 365 Hydro Essence Versus Laneige Cream Skin Cerapeptide Toner & Moisturizer
Aestura Atobarrier 365 Hydro Essence Versus Laneige Cream Skin Cerapeptide Toner & Moisturizer This hydrating essence is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to hydrate skin and strengthen the skin barrier. This hydrating toner is fo
Aestura Atobarrier 365 Hydro Essence Versus Laneige Cream Skin Cerapeptide Toner & Moisturizer
This hydrating essence is formulated around Squalane and Hydroxypropyl Bispalmitamide Mea to hydrate skin and strengthen the skin barrier.
This hydrating toner is formulated around Limnanthes Alba Seed Oil and Ceramide NP to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Glycerin
Squalane
1,2-Hexanediol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Carbomer
Tromethamine
Glyceryl Caprylate
Ethylhexylglycerin
Disodium EDTA
Natto Gum
Stearic Acid
Hydroxypropyl Bispalmitamide Mea
Mannitol
PCA
Lactic Acid
Glucose
Glycine
Urea
Sodium Glycerophosphate
Serine
Glutamic Acid
Tocopherol
Acrylates/Ammonium Methacrylate Copolymer
Potassium Magnesium Aspartate
Aspartic Acid
Leucine
Sodium Chloride
Alanine
Lysine
Arginine
Calcium Gluconate
Magnesium Gluconate
Tyrosine
Phenylalanine
Proline
Threonine
Valine
Isoleucine
Citric Acid
Cholesterol
Histidine
Silica
Acetyl Glucosamine
Creatine
Uric Acid
Cysteine
Methionine
Water, Butylene Glycol, Glycerin, Squalane, 1,2-Hexanediol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Tromethamine, Glyceryl Caprylate, Ethylhexylglycerin, Disodium EDTA, Natto Gum, Stearic Acid, Hydroxypropyl Bispalmitamide Mea, Mannitol, PCA, Lactic Acid, Glucose, Glycine, Urea, Sodium Glycerophosphate, Serine, Glutamic Acid, Tocopherol, Acrylates/Ammonium Methacrylate Copolymer, Potassium Magnesium Aspartate, Aspartic Acid, Leucine, Sodium Chloride, Alanine, Lysine, Arginine, Calcium Gluconate, Magnesium Gluconate, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Citric Acid, Cholesterol, Histidine, Silica, Acetyl Glucosamine, Creatine, Uric Acid, Cysteine, Methionine
Limnanthes Alba Seed Oil
Isopentyldiol
Polyglyceryl-10 Stearate
Glyceryl Stearate Citrate
Sodium Stearoyl Glutamate
Inulin Lauryl Carbamate
Propanediol
Acrylates/Stearyl Methacrylate Copolymer
Tremella Fuciformis Sporocarp Extract
Hyaluronic Acid
Camellia Sinensis Leaf Extract
Xanthan Gum
Ceramide NP
Camellia Japonica Flower Extract
Acetyl Tetrapeptide-11
Water, Butylene Glycol, Glycerin, Limnanthes Alba Seed Oil, Isopentyldiol, 1,2-Hexanediol, Squalane, Polyglyceryl-10 Stearate, Glyceryl Stearate Citrate, Sodium Stearoyl Glutamate, Inulin Lauryl Carbamate, Glyceryl Caprylate, Ethylhexylglycerin, Propanediol, Disodium EDTA, Carbomer, Mannitol, Acrylates/Stearyl Methacrylate Copolymer, Tremella Fuciformis Sporocarp Extract, Hyaluronic Acid, Camellia Sinensis Leaf Extract, Xanthan Gum, Ceramide NP, Camellia Japonica Flower Extract, Tocopherol, Acetyl Tetrapeptide-11
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.
Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.
As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.
Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.
Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.
Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).
Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.
When found in aqueous solutions, mannitol tends to become acidic. This is because it loses a hydrogen ion. This is why mannitol can often be found with pH adjusting ingredients, such as sodium bicarbonate.
Fun fact: Mannitol can be found in foods as a sweetener. It can be naturally found in mushrooms, algae, fruits, and veggies.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!