Skin science article
Allies of Skin Retinal & Peptides Repair Night Cream Versus Murad Retinol Youth Renewal Serum
Allies of Skin Retinal & Peptides Repair Night Cream Versus Murad Retinol Youth Renewal Serum This anti-aging night moisturizer is formulated around Palmitoyl Tetrapeptide-7 and Niacinamide to soften the look of wrinkles and strengthen the skin barrier. This a
Allies of Skin Retinal & Peptides Repair Night Cream Versus Murad Retinol Youth Renewal Serum
This anti-aging night moisturizer is formulated around Palmitoyl Tetrapeptide-7 and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Retinol and Hydroxypinacolone Retinoate to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Propanediol
Argania Spinosa Kernel Oil
Sodium Acrylates Copolymer
Hydrolyzed Candida Saitoana Extract
Sodium Stearoyl Glutamate
Albizia Julibrissin Bark Extract
Dimethyl Isosorbide
Galactoarabinan
Palmitoyl Tetrapeptide-7
Palmitoyl Oligopeptide
Caprooyl Tetrapeptide-3
Cassia Angustifolia Seed Polysaccharide
Hyaluronic Acid
Oxycoccus Palustris Seed Oil
Rubus Chamaemorus Seed Oil
Niacinamide
Withania Somnifera Root Extract
Citrus Aurantium Dulcis Callus Culture Extract
Retinal
Ellagic Acid
Phenyl T-Butylnitrone
Ergothioneine
Glutathione
Mirabilis Jalapa Flower/Leaf/Stem Extract
N-Hydroxysuccinimide
Chrysin
Glutamylamidoethyl Imidazole
Lonicera Caprifolium Flower Extract
Lonicera Japonica Flower Extract
Lavandula Hybrida Oil
Pentylene Glycol
Butylene Glycol
Cyclodextrin
Caprylyl Glycol
Steareth-20
Citric Acid
Xanthan Gum
Dextran
Acetyl Tributyl Citrate
Potassium Sorbate
Phenoxyethanol
Geraniol
Limonene
Linalool
Water, Glycerin, Caprylic/Capric Triglyceride, Propanediol, Argania Spinosa Kernel Oil, Sodium Acrylates Copolymer, Hydrolyzed Candida Saitoana Extract, Sodium Stearoyl Glutamate, Albizia Julibrissin Bark Extract, Dimethyl Isosorbide, Galactoarabinan, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Caprooyl Tetrapeptide-3, Cassia Angustifolia Seed Polysaccharide, Hyaluronic Acid, Oxycoccus Palustris Seed Oil, Rubus Chamaemorus Seed Oil, Niacinamide, Withania Somnifera Root Extract, Citrus Aurantium Dulcis Callus Culture Extract, Retinal, Ellagic Acid, Phenyl T-Butylnitrone, Ergothioneine, Glutathione, Mirabilis Jalapa Flower/Leaf/Stem Extract, N-Hydroxysuccinimide, Chrysin, Glutamylamidoethyl Imidazole, Lonicera Caprifolium Flower Extract, Lonicera Japonica Flower Extract, Lavandula Hybrida Oil, Pentylene Glycol, Butylene Glycol, Cyclodextrin, Caprylyl Glycol, Steareth-20, Citric Acid, Xanthan Gum, Dextran, Acetyl Tributyl Citrate, Potassium Sorbate, Phenoxyethanol, Geraniol, Limonene, Linalool
Cyclopentasiloxane
Isopropyl Palmitate
C14-22 Alcohols
Polymethylsilsesquioxane
Dimethicone
Glyceryl Stearate
PEG-100 Stearate
Shea Butter Ethyl Esters
Retinol
Hydroxypinacolone Retinoate
Ceramide NP
Sodium Hyaluronate
Solanum Lycopersicum Fruit Extract
Swertia Chirata Extract
Squalane
Punica Granatum Extract
Tocopheryl Acetate
Glycine Soja Extract
Urea
Yeast Amino Acids
Trehalose
Inositol
Taurine
Betaine
Silica
Ethylhexyl Palmitate
Silica Dimethyl Silylate
Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
C12-20 Alkyl Glucoside
Cetyl Palmitate
Laureth-23
Polysorbate 20
Trideceth-6 Phosphate
Synthetic Fluorphlogopite
Ethylhexylglycerin
Chlorphenesin
Disodium EDTA
Sodium Hydroxide
Tris(Tetramethylhydroxypiperidinol)Citrate
Sodium Benzotriazolyl Butylphenol Sulfonate
CI 77891
CI 14700
Alpha-Isomethyl Ionone
Citronellol
Parfum
Water, Cyclopentasiloxane, Isopropyl Palmitate, C14-22 Alcohols, Polymethylsilsesquioxane, Dimethicone, Propanediol, Glyceryl Stearate, PEG-100 Stearate, Shea Butter Ethyl Esters, Retinol, Hydroxypinacolone Retinoate, Ceramide NP, Sodium Hyaluronate, Solanum Lycopersicum Fruit Extract, Swertia Chirata Extract, Squalane, Punica Granatum Extract, Tocopheryl Acetate, Glycine Soja Extract, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Glycerin, Caprylic/Capric Triglyceride, Dimethyl Isosorbide, Silica, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Butylene Glycol, Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, C12-20 Alkyl Glucoside, Cetyl Palmitate, Laureth-23, Polysorbate 20, Trideceth-6 Phosphate, Synthetic Fluorphlogopite, Phenoxyethanol, Ethylhexylglycerin, Chlorphenesin, Disodium EDTA, Sodium Hydroxide, Tris(Tetramethylhydroxypiperidinol)Citrate, Sodium Benzotriazolyl Butylphenol Sulfonate, CI 77891, CI 14700, Alpha-Isomethyl Ionone, Citronellol, Parfum
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Dimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula.
Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed.
It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself).
Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!