Skin science article
Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum Versus Pillowtalk Derm Major Fade Hyper Serum
Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum Versus Pillowtalk Derm Major Fade Hyper Serum This brightening serum is formulated around Tranexamic Acid and Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin. This brigh
Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum Versus Pillowtalk Derm Major Fade Hyper Serum
This brightening serum is formulated around Tranexamic Acid and Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin.
This brightening serum is formulated around Niacinamide and Alpha-Arbutin to fade the look of dark spots and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
C13-15 Alkane
Tranexamic Acid
Glycerin
Alpha-Arbutin
Pentylene Glycol
Tocopheryl Acetate
Palmaria Palmata Extract
Hydrolyzed Pea
Asparagopsis Armata Extract
Ascophyllum Nodosum Extract
Glycyrrhiza Glabra Root Extract
Pancratium Maritimum Extract
Ganoderma Lucidum Extract
Lentinus Edodes Extract
Lactobacillus Ferment
Hydrolyzed Pea Protein
Diacetyl Boldine
Dipotassium Glycyrrhizate
Lactobacillus
Bisabolol
Panthenol
Tocopherol
Glucose
Arginine/Lysine Polypeptide
Pentapeptide-34 Trifluoroacetate
C14-22 Alcohols
Xanthan Gum
Hydrogenated Starch Hydrolysate
Hydroxyacetophenone
Sorbitan Caprylate
1,2-Hexanediol
Caprylyl Glycol
C12-20 Alkyl Glucoside
Propanediol
Carbomer
Sodium Phytate
Butylene Glycol
Sodium Chloride
Sodium Succinate
Sorbic Acid
Sodium Benzoate
Potassium Sorbate
Phenoxyethanol
Water, Caprylic/Capric Triglyceride, C13-15 Alkane, Tranexamic Acid, Glycerin, Alpha-Arbutin, Pentylene Glycol, Tocopheryl Acetate, Palmaria Palmata Extract, Hydrolyzed Pea, Asparagopsis Armata Extract, Ascophyllum Nodosum Extract, Glycyrrhiza Glabra Root Extract, Pancratium Maritimum Extract, Ganoderma Lucidum Extract, Lentinus Edodes Extract, Lactobacillus Ferment, Hydrolyzed Pea Protein, Diacetyl Boldine, Dipotassium Glycyrrhizate, Lactobacillus, Bisabolol, Panthenol, Tocopherol, Glucose, Arginine/Lysine Polypeptide, Pentapeptide-34 Trifluoroacetate, C14-22 Alcohols, Xanthan Gum, Hydrogenated Starch Hydrolysate, Hydroxyacetophenone, Sorbitan Caprylate, 1,2-Hexanediol, Caprylyl Glycol, C12-20 Alkyl Glucoside, Propanediol, Carbomer, Sodium Phytate, Butylene Glycol, Sodium Chloride, Sodium Succinate, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol
Niacinamide
Butyrospermum Parkii Butter
Squalane
Cetearyl Olivate
Dimethicone
Cetyl Alcohol
Sorbitan Olivate
Kojic Acid
Diglucosyl Gallic Acid
Persea Gratissima Oil
Sclerotium Gum
Citric Acid
Hexylene Glycol
Ethylhexylglycerin
Mica
CI 77891
Water, Niacinamide, Glycerin, Caprylic/Capric Triglyceride, Pentylene Glycol, Alpha-Arbutin, Butyrospermum Parkii Butter, Squalane, Cetearyl Olivate, Dimethicone, Cetyl Alcohol, Sorbitan Olivate, Kojic Acid, Diglucosyl Gallic Acid, Glycyrrhiza Glabra Root Extract, Persea Gratissima Oil, Sclerotium Gum, Xanthan Gum, Citric Acid, Sodium Phytate, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol, Mica, CI 77891
Reviews
Be the first to review
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alpha-Arbutin is a brightening active used to fade dark spots, melasma, and post-acne marks. Structurally, it is a hydroquinone with a sugar molecule attached (but is much gentler than raw hydroquinone).
It has a pretty elegant way of working; it slots into tyrosinase, or the key enzyme that your skin uses to make melanin), and competitively blocks it so your skin produces less pigment over time.
There are two forms of arbutin and alpha is the better one to reach for: it works at lower amounts, absorbs into skin more easily, and has a strong safety record.
The science backs this up too: lab and animal studies confirm it lowers melanin by blocking tyosinase and the more you use (up to a point), the more it works.
Human studies look good too.
A 2024 trial found a cream with 5% alpha-arbutin and 2% kojic acid worked about as well as a prescription melasma cream but with fewer side effects. Another study showed 2% alpha-arbutin paired with 10% Trihydroxybenzoic Acid Glucoside and sunscreen faded dark spots and melasma without causing irritation.
Concentration-wise, most serums land in the 1-2% range.
The EU's Scientific Committee on Consumer Safety concluded that alpha-arbutin is safe in face creams up to 2% and body lotions up to 0.5%.
Overall, this is a well-studied and low-irritation brightener that's a great pick for anyone dealing with uneven skin tone. It also pairs well with vitamin C, niacinamide, and sunscreen.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.