Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Altilis beauty InflorEssence Moisturizer Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer

Altilis beauty InflorEssence Moisturizer Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer This calming moisturizer is formulated around Centella Asiatica Extract and Resveratrol to calm redness and strengthen the skin barrier. This barrier-repair

Altilis beauty InflorEssence Moisturizer Versus Olehenriksen Strength Trainer Peptide Boost Moisturizer

This calming moisturizer is formulated around Centella Asiatica Extract and Resveratrol to calm redness and strengthen the skin barrier.

This barrier-repair moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Aleurites Moluccanus Seed Oil

Cyclopia Genistoides Leaf Extract

Centella Asiatica Extract

Glyceryl Stearate

Artocarpus Altilis Flower Extract

Sodium Hyaluronate

Resveratrol

Aloe Barbadensis Leaf Polysaccharides

Ferulic Acid

Magnesium Ascorbyl Phosphate

Ceramide NP

Ceramide AP

Ceramide EOP

Phytosphingosine

Cholesterol

Sodium Lauroyl Lactylate

Carbomer

Xanthan Gum

Glyceryl Stearate Citrate

Citric Acid

Benzyl Alcohol

Dehydroacetic Acid

Water, Aleurites Moluccanus Seed Oil, Cyclopia Genistoides Leaf Extract, Centella Asiatica Extract, Glyceryl Stearate, Artocarpus Altilis Flower Extract, Sodium Hyaluronate, Resveratrol, Aloe Barbadensis Leaf Polysaccharides, Ferulic Acid, Magnesium Ascorbyl Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Carbomer, Xanthan Gum, Glyceryl Stearate Citrate, Citric Acid, Benzyl Alcohol, Dehydroacetic Acid

Propanediol

Dicaprylyl Carbonate

Glycerin

Methylpropanediol

Cetearyl Alcohol

Stearyl Alcohol

Mangifera Indica Seed Butter

Niacinamide

Acetyl Hexapeptide-1

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Acetyl Tetrapeptide-2

Acetyl Dipeptide-1 Cetyl Ester

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Carnosine

Collagen

Serine

Alanine

Glycine

Glutamic Acid

Lysine Hcl

Threonine

Arginine

Proline

Hyaluronic Acid

Linoleic Acid

Linolenic Acid

Sodium PCA

Sodium Lactate

Panthenol

Tocopherol

Tocopheryl Acetate

Betaine

PCA

Cyanocobalamin

Xylitol

Anhydroxylitol

Xylitylglucoside

Sorbitan Olivate

Hydroxyethylcellulose

Cetearyl Olivate

Sorbitan Laurate

Polysorbate 60

Butylene Glycol

Hydroxyacetophenone

Glycine Soja Oil

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Polysorbate 20

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Dimethicone

Sodium Phytate

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Leuconostoc/Radish Root Ferment Filtrate

Caprylyl Glycol

Ethylhexylglycerin

Phenoxyethanol

Parfum

Citral

Limonene

Linalool

Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Methylpropanediol, Cetearyl Alcohol, Stearyl Alcohol, Mangifera Indica Seed Butter, Niacinamide, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Dipeptide-1 Cetyl Ester, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carnosine, Ceramide NP, Ceramide AP, Ceramide EOP, Collagen, Serine, Alanine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Arginine, Proline, Hyaluronic Acid, Sodium Hyaluronate, Linoleic Acid, Linolenic Acid, Sodium PCA, Sodium Lactate, Panthenol, Tocopherol, Tocopheryl Acetate, Betaine, PCA, Cyanocobalamin, Xylitol, Anhydroxylitol, Xylitylglucoside, Sorbitan Olivate, Carbomer, Hydroxyethylcellulose, Xanthan Gum, Cetearyl Olivate, Sorbitan Laurate, Phytosphingosine, Cholesterol, Polysorbate 60, Butylene Glycol, Hydroxyacetophenone, Glycine Soja Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Dimethicone, Sodium Phytate, Sodium Lauroyl Lactylate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Leuconostoc/Radish Root Ferment Filtrate, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Parfum, Citral, Limonene, Linalool

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.

You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Ceramide EOP is formally known as Ceramide 1.

It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).

Low levels of Ceramide EOP have been found in people with eczema and psoriasis.

Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.

In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.

You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.

It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Phytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.

Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.

Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.

Fun fact: Phytosphingosine is abundant in plants and fungi.

More ingredients that help boost collagen in skin:

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Lauroyl Lactylate (SLL) is a mild, plant-derived surfactant made by combining lauric acid with lactic acid.

It has two main jobs in a formula:

A perk of this ingredient is that it leaves skin feeling soft and silky after rinsing. This is why you'll even see it in baby washes.

Another perk? The lauric acid backbone gives it mild antimicrobial activity and lauric acid itself has been shown to suppress acne-causing bacteria in lab studies.

In 2023, scientists took a close look at how SLL behaves and found it can break apart the fatty outer layers of cells. This is basically why it cleans well and can fight off certain microbes.

The Cosmetic Ingredient Review (CIR) Expert Panel has reviewed it and concluded it's safe as used.

A 2017 survey showed concentrations up to 10% are used in rinse-off cleansers and roughly 0.5-5% being typical in skincare.

Animal and reconstructed-skin testing found it to be non-irritating at 10%, and it's well tolerated even on sensitive skin. The only caveat is to patch test if you have a lactic acid allergy.

As a lactylate salt used at low co-emulsifier concentrations, this ingredient is less likely to break down and release free lauric acid on skin. This ingredient is fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Citral is the molecule responsible for the fresh lemon scent in lemon, lime, and lemongrass. It is a fragrance ingredient that can be created from plant essential oils or synthetically.
  7. 07Though Citral has documented antimicrobial activity against acne bacteria (which is where the marketing claims about it being good for acne-prone skin originate), real formulas use it at fragrance-level concentrations under 1% so there's likely no s…
  8. 08You should know this ingredient is a known EU fragrance allergen.
  9. 09Animal studies classifies this ingredient as a weak-to-moderate skin sensitizer and clinical patch testing on eczema patients confirmed it to be both a contact allergen and irritant.
  10. 10The term 'citral' is a collective term for two geometric isomers: geranial/Citral A and neral/Citral B.
  11. 11The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, the…
  12. 12Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
  13. 13What it does:
  14. 14Dimethicone comes in different viscosities:
  15. 15Depending on the viscosity, dimethicone has different properties.
  16. 16Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
  17. 17This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
  18. 18Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
  19. 19Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
  20. 20The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure …
Source · skinsort.com
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Product index

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Comparison edit

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