Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Anua Niacinamide 10% + TXA 4% Serum Versus Torriden Dive-In Low-Molecular Hyaluronic Acid Serum

Anua Niacinamide 10% + TXA 4% Serum Versus Torriden Dive-In Low-Molecular Hyaluronic Acid Serum This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin. This hydrating serum is f

Anua Niacinamide 10% + TXA 4% Serum Versus Torriden Dive-In Low-Molecular Hyaluronic Acid Serum

This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.

This hydrating serum is formulated around Panthenol and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Niacinamide

Tranexamic Acid

Butylene Glycol

Diethoxyethyl Succinate

1,2-Hexanediol

Arbutin

Sodium Hyaluronate

Alpha-Arbutin

Coccinia Indica Fruit Extract

Eclipta Prostrata Extract

Macadamia Integrifolia Seed Oil

Olea Europaea Fruit Oil

Simmondsia Chinensis Seed Oil

Vitis Vinifera Seed Oil

Theobroma Cacao Extract

Hydrolyzed Hyaluronic Acid

Chamaecyparis Obtusa Leaf Extract

Prunus Persica Flower Extract

Camellia Sinensis Seed Oil

Yeast Ferment Extract

Centella Asiatica Extract

Artemisia Princeps Leaf Extract

Candida Bombicola/Glucose/Methyl Rapeseedate Ferment

Hyaluronic Acid

Pentylene Glycol

Betaine Salicylate

Sucrose Palmitate

Hydrogenated Lecithin

Gellan Gum

Sodium Phytate

Cellulose

Caprylic/Capric Triglyceride

Panthenol

Cyanocobalamin

Polyglutamic Acid

3-O-Ethyl Ascorbic Acid

Ceramide NP

Dextrin

Asiaticoside

Madecassic Acid

Asiatic Acid

Dimethylsilanol Hyaluronate

Hydrolyzed Sodium Hyaluronate

Potassium Hyaluronate

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Sodium Hyaluronate Dimethylsilanol

Sodium Acetylated Hyaluronate

Xanthan Gum

Water, Glycerin, Niacinamide, Tranexamic Acid, Butylene Glycol, Diethoxyethyl Succinate, 1,2-Hexanediol, Arbutin, Sodium Hyaluronate, Alpha-Arbutin, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Macadamia Integrifolia Seed Oil, Olea Europaea Fruit Oil, Simmondsia Chinensis Seed Oil, Vitis Vinifera Seed Oil, Theobroma Cacao Extract, Hydrolyzed Hyaluronic Acid, Chamaecyparis Obtusa Leaf Extract, Prunus Persica Flower Extract, Camellia Sinensis Seed Oil, Yeast Ferment Extract, Centella Asiatica Extract, Artemisia Princeps Leaf Extract, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, Hyaluronic Acid, Pentylene Glycol, Betaine Salicylate, Sucrose Palmitate, Hydrogenated Lecithin, Gellan Gum, Sodium Phytate, Cellulose, Caprylic/Capric Triglyceride, Panthenol, Cyanocobalamin, Polyglutamic Acid, 3-O-Ethyl Ascorbic Acid, Ceramide NP, Dextrin, Asiaticoside, Madecassic Acid, Asiatic Acid, Dimethylsilanol Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, Xanthan Gum

Dipropylene Glycol

Allantoin

Ectoin

Glycyrrhiza Glabra Root Extract

2,3-Butanediol

Trehalose

Betaine

Propanediol

Portulaca Oleracea Extract

Hamamelis Virginiana Leaf Extract

Madecassoside

Beta-Glucan

Malachite Extract

Cholesterol

Glyceryl Acrylate/Acrylic Acid Copolymer

Pvm/Ma Copolymer

Polyglyceryl-10 Laurate

Tromethamine

Carbomer

Ethylhexylglycerin

Scutellaria Baicalensis Root Extract

Paeonia Suffruticosa Root Extract

Water, Butylene Glycol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Allantoin, Ectoin, Glycyrrhiza Glabra Root Extract, 2,3-Butanediol, Trehalose, Betaine, Propanediol, Portulaca Oleracea Extract, Hamamelis Virginiana Leaf Extract, Madecassoside, Madecassic Acid, Ceramide NP, Beta-Glucan, Malachite Extract, Cholesterol, Pentylene Glycol, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Polyglyceryl-10 Laurate, Xanthan Gum, Tromethamine, Carbomer, Ethylhexylglycerin, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.

It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.

Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.

Most formulations will combine all sizes to get the best of both worlds.

Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Madecassic Acid is one of the four star actives in Centella Asiatica. In skincare, it earns its keep as a calming and repairing ingredient.

It works through the same core pathways as the rest of the centella family.

First, it turns down inflammation so it helps with things like redness and general upset skin.

Second, it acts as an antioxidant which means it helps protect skin from daily stress and damage.

And third, it nudges the skin to make more collagen and rebuild its support structure.

That combination is why the whole Centella family is known for calming skin, strengthening the barrier, fading redness, and giving anti-aging benefits.

It's worth being honest about the evidence here; a lot of the strongest data is on the full extract or a Madecassoside/Asiaticoside rather than Madecassic Acid alone. Reviewers also note more long-term clinical trials are needed to confirm the full potential.

Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%.

Finished products typically run somewhere in the 0.1-10% range depending on the format.

In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects. And a mascara with 0.5% Madecassoside caused neither irritation nor sensitization in 109 subjects.

Allergy risk is very low, but not zero. Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hyaluronic Acids help moisturize, soothe, and protect the skin.

Read about common types of Hyaluronic Acid here:

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.

A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.

A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.

More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Propylene Glycol
  3. 03Glycerin
  4. 04Butylene Glycol
  5. 05Ceramide AP
  6. 061,2-Hexanediol
  7. 07Hydrolyzed Hyaluronic Acid
  8. 08Sodium Hyaluronate
  9. 09Tropaeolum Majus Flower/Leaf/Stem Extract
  10. 10Phenoxyethanol
  11. 11Trisodium Ethylenediamine Disuccinate
  12. 12Citric Acid
  13. 13Ethylhexylglycerin
  14. 14Water, Propylene Glycol, Glycerin, Butylene Glycol, Ceramide AP, 1,2-Hexanediol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Tropaeolum Majus Flower/Leaf/Stem Extract, Phenoxyethanol, Trisodium Ethylenediamine Disuccinate, Citric Acid, Ethylhexy…
  15. 15Propanediol
  16. 16Pentylene Glycol
  17. 17Niacinamide
  18. 18PEG-60 Hydrogenated Castor Oil
  19. 19Ammonium Acryloyldimethyltaurate/Vp Copolymer
  20. 20Caprylyl Glycol
Source · skinsort.com
02

Product index

Related product references

Product

Yeouth Hyaluronic Acid Serum

Yeouth Hyaluronic Acid Serum Yeouth Hyaluronic Acid Serum ingredients explained: Hyaluronic Acid, Phenoxyethanol Show all ingredients by function Hyaluronic Acid skin-identical ingredient, …

Source: incidecoder.comView reference →

Product

Swanson Hyaluronic Acid Serum

Swanson Hyaluronic Acid Serum Swanson Hyaluronic Acid Serum ingredients explained: Purified (Deionized) Water, Vegetable Glycerin, Aloe Barbadensis (Aloe Vera) Leaf Gel, Sodium Hyaluronate …

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01What Skin Types Should Use Hyaluronic Acid?

“Hyaluronic acid is particularly helpful for those experiencing dry skin, and for those desiring a plumping effect,” explains Dr. King. But, if you have an oily skin type, don’t discredit hyaluronic acid from your routine just yet. Despite the excess sebum that you may experience, it’s important to keep your skin hydrated so that it doesn’t overcompensate and produce even more oil as a result. Besides your skin type, you should also look at the condition of your skin to decide if it’s time to begin using hyaluronic acid. “If your skin is starting to look dull, flaky and you’re seeing more pronounced fine lines and wrinkles, that’s a pretty good indication that it’s time to add this ingredient to your routine,” adds O’Conner.

Source · www.skincare.com
02Is Serum Good for All Skin Types?

Serums are a form of skincare that can be added to any routine no matter what your skin type is. All skin types can benefit from the use of a serum since there are so many different formulations that can target specific skincare concerns. “Serums are used for hydration,to aid [or] maintain the skin barrier, or treat skin issues like acne or rosacea,” says Dr. Lewis. The type of serum that you may use should depend on the skin issue you’re trying to target. Think of serums as a treatment for the skin. “Some serums can reverse damage and help prevent free radicals that cause the signs of aging skin,” adds Dr. Lewis.

Source · www.skincare.com