APLB Collagen EGF Peptide Ampoule Serum Versus SKIN1004 Madagascar Centella Ampoule

APLB Collagen EGF Peptide Ampoule Serum Versus SKIN1004 Madagascar Centella Ampoule

This anti-aging serum is formulated around Centella Asiatica Extract and Sh-Oligopeptide-1 to soften the look of wrinkles and calm redness.

This calming ampoule is formulated around Centella Asiatica Extract to calm redness and strengthen the skin barrier.

What's inside

Key Ingredients

No key ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Centella Asiatica Extract 35.7%

Butylene Glycol

Propanediol

Glycerin

Diethoxyethyl Succinate

Hydrolyzed Collagen

Sh-Oligopeptide-1

Madecassic Acid

Asiaticoside

Asiatic Acid

Squalane

Solanum Melongena Fruit Extract

Melaleuca Alternifolia Leaf Extract

Beta-Glucan

Hippophae Rhamnoides Fruit Extract

Nelumbo Nucifera Extract

Artemisia Annua Extract

Oryza Sativa Extract

Saccharomyces Ferment

Dipropylene Glycol

Sodium Citrate

Sodium Hyaluronate

Allantoin

Cellulose Gum

Disodium EDTA

Glyceryl Acrylate/Acrylic Acid Copolymer

Citric Acid

Xanthan Gum

Inulin

Cellulose

Glucose

Fructose

Panthenol

Ethylhexylglycerin

Hydroxyacetophenone

Sodium Polyacryloyldimethyl Taurate

Dipotassium Glycyrrhizate

1,2-Hexanediol

Water, Centella Asiatica Extract 35.7%, Butylene Glycol, Propanediol, Glycerin, Diethoxyethyl Succinate, Hydrolyzed Collagen, Sh-Oligopeptide-1, Madecassic Acid, Asiaticoside, Asiatic Acid, Squalane, Solanum Melongena Fruit Extract, Melaleuca Alternifolia Leaf Extract, Beta-Glucan, Hippophae Rhamnoides Fruit Extract, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa Extract, Saccharomyces Ferment, Dipropylene Glycol, Sodium Citrate, Sodium Hyaluronate, Allantoin, Cellulose Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Citric Acid, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Panthenol, Ethylhexylglycerin, Hydroxyacetophenone, Sodium Polyacryloyldimethyl Taurate, Dipotassium Glycyrrhizate, 1,2-Hexanediol

Centella Asiatica Extract

Water, Glycerin, Butylene Glycol, Centella Asiatica Extract, 1,2-Hexanediol, Cellulose Gum, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.

As an emulsifier, cellulose gum specifically thicken the texture of water-based products.

This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.

Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.

That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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