Skin science article
Augustinus Bader The Ultimate Soothing Cream Versus Drunk Elephant Protini Polypeptide Cream
Augustinus Bader The Ultimate Soothing Cream Versus Drunk Elephant Protini Polypeptide Cream This calming moisturizer is formulated around Oenothera Biennis Oil and Panthenol to calm redness and strengthen the skin barrier. This anti-aging moisturizer is formu
Augustinus Bader The Ultimate Soothing Cream Versus Drunk Elephant Protini Polypeptide Cream
This calming moisturizer is formulated around Oenothera Biennis Oil and Panthenol to calm redness and strengthen the skin barrier.
This anti-aging moisturizer is formulated around Sclerocarya Birrea Seed Oil and Sh-Oligopeptide-1 to soften the look of wrinkles and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Caprylic/Capric Triglyceride
Glycerin
C10-18 Triglycerides
Dicaprylyl Ether
Butyrospermum Parkii Butter
Cetearyl Alcohol
Glyceryl Stearate Citrate
Glyceryl Stearate
Vegetable Oil
Octyldodecanol
Nigella Sativa Seed Oil
Oenothera Biennis Oil
Panthenol
Glyceryl Caprylate
Hydrogenated Vegetable Oil
Niacinamide
Sodium Stearoyl Glutamate
Zinc PCA
Polyacrylate Crosspolymer-6
Sodium Benzoate
Euphorbia Cerifera Cera
Hydrolyzed Rice Protein
Maltodextrin
Citric Acid
Totarol
Camellia Sinensis Leaf Extract
Hydrogenated Lecithin
Tocopheryl Acetate
Xanthan Gum
Tocopherol
Alanyl Glutamine
Arginine
Oligopeptide-177
Potassium Sorbate
Sodium Chloride
Phenylalanine
Sisymbrium Irio Seed Oil
Water, Caprylic/Capric Triglyceride, Glycerin, C10-18 Triglycerides, Dicaprylyl Ether, Butyrospermum Parkii Butter, Cetearyl Alcohol, Glyceryl Stearate Citrate, Glyceryl Stearate, Vegetable Oil, Octyldodecanol, Nigella Sativa Seed Oil, Oenothera Biennis Oil, Panthenol, Glyceryl Caprylate, Hydrogenated Vegetable Oil, Niacinamide, Sodium Stearoyl Glutamate, Zinc PCA, Polyacrylate Crosspolymer-6, Sodium Benzoate, Euphorbia Cerifera Cera, Hydrolyzed Rice Protein, Maltodextrin, Citric Acid, Totarol, Camellia Sinensis Leaf Extract, Hydrogenated Lecithin, Tocopheryl Acetate, Xanthan Gum, Tocopherol, Alanyl Glutamine, Arginine, Oligopeptide-177, Potassium Sorbate, Sodium Chloride, Phenylalanine, Sisymbrium Irio Seed Oil
Dicaprylyl Carbonate
Cetearyl Olivate
Sorbitan Olivate
Sclerocarya Birrea Seed Oil
Bacillus/Folic Acid Ferment Filtrate Extract
Nymphaea Alba Root Extract
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Sh-Polypeptide-9
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Heptapeptide-15 Palmitate
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Alanine
Glycine
Histidine
Isoleucine
Proline
Serine
Threonine
Valine
Acetyl Glutamine
Coconut Alkanes
Coco-Caprylate/Caprate
Sodium Hyaluronate
Aspartic Acid
Linoleic Acid
Linolenic Acid
Lecithin
Butylene Glycol
Polyvinyl Alcohol
Sodium Lactate
Sodium PCA
PCA
Sorbitan Isostearate
Carbomer
Polysorbate 20
Polysorbate 60
Lactic Acid/Glycolic Acid Copolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Isomalt
1,2-Hexanediol
Caprylyl Glycol
Chlorphenesin
Phenoxyethanol
Phenylpropanol
Symphytum Officinale Callus Culture Extract
Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.
Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.
As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.
Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.
Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.
Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).
Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.