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Avène Cicalfate+ Repairing Protective Cream Versus Dermatica Nourishing Ceramide + Peptide Moisturizer

Avène Cicalfate+ Repairing Protective Cream Versus Dermatica Nourishing Ceramide + Peptide Moisturizer This moisturizer is formulated around Zinc Sulfate to control oil. This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to streng

By Peptide Skincare & Beauty Editorial TeamPublished

Avène Cicalfate+ Repairing Protective Cream Versus Dermatica Nourishing Ceramide + Peptide Moisturizer

This moisturizer is formulated around Zinc Sulfate to control oil.

This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

No key ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Paraffinum Liquidum

Glycerin

Hydrogenated Vegetable Oil

Zinc Oxide

Propylene Glycol

Polyglyceryl-2 Sesquiisostearate

PEG-22/Dodecyl Glycol Copolymer

Aluminum Stearate

Aquaphilus Dolomiae Ferment Filtrate

Arginine

Beeswax

Copper Sulfate

Magnesium Stearate

Magnesium Sulfate

Microcrystalline Wax

Tromethamine

Zinc Sulfate

Water, Caprylic/Capric Triglyceride, Paraffinum Liquidum, Glycerin, Hydrogenated Vegetable Oil, Zinc Oxide, Propylene Glycol, Polyglyceryl-2 Sesquiisostearate, PEG-22/Dodecyl Glycol Copolymer, Aluminum Stearate, Aquaphilus Dolomiae Ferment Filtrate, Arginine, Beeswax, Copper Sulfate, Magnesium Stearate, Magnesium Sulfate, Microcrystalline Wax, Tromethamine, Zinc Sulfate

Cetearyl Alcohol

Butyrospermum Parkii Butter

C12-15 Alkyl Benzoate

Niacinamide

Vitis Vinifera Oil

Dimethicone

Panthenol

Sorbitan Stearate

Squalane

Tocopheryl Acetate

Phenoxyethanol

Butylene Glycol

Polyacrylate Crosspolymer-6

Sodium Lauroyl Lactylate

Centella Asiatica Extract

Ethylhexylglycerin

Sodium Hyaluronate

Trisodium Ethylenediamine Disuccinate

Citric Acid

Carbomer

Ceramide NP

Ceramide AP

Phytosphingosine

Cholesterol

Polysorbate 20

Xanthan Gum

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Ceramide EOP

Water, Cetearyl Alcohol, Glycerin, Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Niacinamide, Vitis Vinifera Oil, Dimethicone, Panthenol, Sorbitan Stearate, Squalane, Tocopheryl Acetate, Phenoxyethanol, Butylene Glycol, Polyacrylate Crosspolymer-6, Sodium Lauroyl Lactylate, Centella Asiatica Extract, Ethylhexylglycerin, Sodium Hyaluronate, Trisodium Ethylenediamine Disuccinate, Citric Acid, Carbomer, Ceramide NP, Ceramide AP, Phytosphingosine, Cholesterol, Polysorbate 20, Xanthan Gum, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  4. 04Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  5. 05It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  6. 06Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  7. 07A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  8. 08Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
  9. 09Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
  10. 10However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
  11. 11Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
  12. 12In skincare formulas, citric acid can:
  13. 13While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
  14. 14Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
  15. 15Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
  16. 16However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's…
  17. 17Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  18. 18Topically, glycerin does several things at once:
  19. 19Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  20. 20Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
Source · skinsort.com ⟶
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