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AXIS - Y Artichoke Intensive Skin Barrier Ampoule Versus Cetaphil Healthy Renew Purified Peptides Face Serum

AXIS - Y Artichoke Intensive Skin Barrier Ampoule Versus Cetaphil Healthy Renew Purified Peptides Face Serum This barrier-repair ampoule is formulated around Centella Asiatica Extract to strengthen the skin barrier and calm redness. This anti-aging serum is fo

AXIS - Y Artichoke Intensive Skin Barrier Ampoule Versus Cetaphil Healthy Renew Purified Peptides Face Serum

This barrier-repair ampoule is formulated around Centella Asiatica Extract to strengthen the skin barrier and calm redness.

This anti-aging serum is formulated around Panthenol and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Ingredients Side-by-side

Water

Aloe Barbadensis Leaf Water

Butylene Glycol

Sodium Hyaluronate

Centella Asiatica Extract

Glycerin

Betaine

Propanediol

Glycyrrhiza Uralensis Root Extract

Hieracium Umbellatum Extract

Cynara Scolymus Leaf Extract

Sorbitol

Aloe Barbadensis Leaf Extract

Dioscorea Japonica Root Extract

Laminaria Japonica Extract

1,2-Hexanediol

Xanthan Gum

Carbomer

Linum Usitatissimum Seed Extract

Hibiscus Esculentus Fruit Extract

Aloe Barbadensis Leaf Juice

Arctium Lappa Root Extract

Hibiscus Mutabilis Flower Extract

Corchorus Olitorius Leaf Extract

Rheum Palmatum Root Extract

Althaea Rosea Flower Extract

Dimethyl Sulfone

Chlorphenesin

Ethylhexylglycerin

Polyglutamic Acid

Beta-Glucan

Arginine

Allantoin

Adenosine

Water, Aloe Barbadensis Leaf Water, Butylene Glycol, Sodium Hyaluronate, Centella Asiatica Extract, Glycerin, Betaine, Propanediol, Glycyrrhiza Uralensis Root Extract, Hieracium Umbellatum Extract, Cynara Scolymus Leaf Extract, Sorbitol, Aloe Barbadensis Leaf Extract, Dioscorea Japonica Root Extract, Laminaria Japonica Extract, 1,2-Hexanediol, Xanthan Gum, Carbomer, Linum Usitatissimum Seed Extract, Hibiscus Esculentus Fruit Extract, Aloe Barbadensis Leaf Juice, Arctium Lappa Root Extract, Hibiscus Mutabilis Flower Extract, Corchorus Olitorius Leaf Extract, Rheum Palmatum Root Extract, Althaea Rosea Flower Extract, Dimethyl Sulfone, Chlorphenesin, Ethylhexylglycerin, Polyglutamic Acid, Beta-Glucan, Arginine, Allantoin, Adenosine

Panthenol

Niacinamide

Cetyl Ethylhexanoate

Hydrogenated Polydecene

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Oryza Sativa Lees Extract

Leontopodium Alpinum Extract

Calcium Alginate

Hydrolyzed Soy Flour

Agar

Trisodium Ethylenediamine Disuccinate

Synthetic Fluorphlogopite

Caprylyl Glycol

Iron Oxides

Citric Acid

Sodium Benzoate

Potassium Sorbate

Buddleja Davidii Extract

Thymus Vulgaris Extract

Tocopherol

Water, Butylene Glycol, Glycerin, Panthenol, 1,2-Hexanediol, Niacinamide, Cetyl Ethylhexanoate, Hydrogenated Polydecene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Oryza Sativa Lees Extract, Leontopodium Alpinum Extract, Calcium Alginate, Propanediol, Hydrolyzed Soy Flour, Ethylhexylglycerin, Agar, Adenosine, Trisodium Ethylenediamine Disuccinate, Synthetic Fluorphlogopite, Caprylyl Glycol, Iron Oxides, Citric Acid, Sodium Benzoate, Potassium Sorbate, Buddleja Davidii Extract, Thymus Vulgaris Extract, Tocopherol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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