Skin science article
AXIS - Y Heartleaf My Type Calming Cream Versus Paula's Choice 10% Azelaic Acid Booster
AXIS - Y Heartleaf My Type Calming Cream Versus Paula's Choice 10% Azelaic Acid Booster This calming day moisturizer is formulated around Houttuynia Cordata Extract and Centella Asiatica Extract to calm redness and hydrate skin. This calming treatment is formu
AXIS - Y Heartleaf My Type Calming Cream Versus Paula's Choice 10% Azelaic Acid Booster
This calming day moisturizer is formulated around Houttuynia Cordata Extract and Centella Asiatica Extract to calm redness and hydrate skin.
This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Propanediol
Glycerin
Sodium Hyaluronate
Butylene Glycol
Sorbitol
Isohexadecane
Caprylic/Capric Triglyceride
Houttuynia Cordata Extract
Betaine
Centella Asiatica Extract
Glyceryl Stearate
Salvia Officinalis Extract
Glycyrrhiza Glabra Root Extract
Sorghum Bicolor Leaf/Stem Extract
Aspergillus Ferment
Chlorphenesin
Arginine
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Allantoin
Sorbitan Sesquioleate
Ethylhexylglycerin
Xanthan Gum
Guaiazulene
Water, Propanediol, Glycerin, Sodium Hyaluronate, Butylene Glycol, Sorbitol, Isohexadecane, Caprylic/Capric Triglyceride, Houttuynia Cordata Extract, Betaine, Centella Asiatica Extract, Glyceryl Stearate, Salvia Officinalis Extract, Glycyrrhiza Glabra Root Extract, Sorghum Bicolor Leaf/Stem Extract, Aspergillus Ferment, Chlorphenesin, Arginine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sorbitan Sesquioleate, Ethylhexylglycerin, Xanthan Gum, Guaiazulene
Azelaic Acid
C12-15 Alkyl Benzoate
Methyl Glucose Sesquistearate
Cetearyl Alcohol
Dimethicone
Salicylic Acid
Adenosine
Boerhavia Diffusa Root Extract
Bisabolol
Cyclopentasiloxane
Sclerotium Gum
Phenoxyethanol
Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.