AXIS - Y Vegan Collagen Eye Serum Versus Naturium Multi-Peptide Eye Cream

AXIS - Y Vegan Collagen Eye Serum Versus Naturium Multi-Peptide Eye Cream

This anti-aging eye moisturizer is formulated around Niacinamide and Palmitoyl Pentapeptide-4 to soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Methylpropanediol

Glycerin

1,2-Hexanediol

Niacinamide

Adenosine

Collagen

Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid

Sodium Acetylated Hyaluronate

Tripeptide-1

Palmitoyl Pentapeptide-4

Hexapeptide-9

Acetyl Hexapeptide-8

Copper Tripeptide-1

Pyrus Malus Fruit Extract

Prunus Mume Fruit Extract

Vitis Vinifera Fruit Extract

Helianthus Annuus Seed Oil

Simmondsia Chinensis Seed Oil

Limnanthes Alba Seed Oil

Carica Papaya Fruit Extract

Centella Asiatica Extract

Ficus Carica Fruit Extract

Ulmus Davidiana Root Extract

Amaranthus Caudatus Seed Extract

Ceramide NP

Hydrogenated Lecithin

Leuconostoc/Radish Root Ferment Filtrate

Butylene Glycol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

C13-14 Alkane

Sodium Acrylic Acid/Ma Copolymer

C15-23 Alkane

Ethylhexylglycerin

Decyl Glucoside

Caprylyl Glycol

Polyglyceryl-10 Stearate

Tocopherol

Water, Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Adenosine, Collagen, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Tripeptide-1, Palmitoyl Pentapeptide-4, Hexapeptide-9, Acetyl Hexapeptide-8, Copper Tripeptide-1, Pyrus Malus Fruit Extract, Prunus Mume Fruit Extract, Vitis Vinifera Fruit Extract, Helianthus Annuus Seed Oil, Simmondsia Chinensis Seed Oil, Limnanthes Alba Seed Oil, Carica Papaya Fruit Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Ulmus Davidiana Root Extract, Amaranthus Caudatus Seed Extract, Ceramide NP, Hydrogenated Lecithin, Leuconostoc/Radish Root Ferment Filtrate, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, C13-14 Alkane, Sodium Acrylic Acid/Ma Copolymer, C15-23 Alkane, Ethylhexylglycerin, Decyl Glucoside, Caprylyl Glycol, Polyglyceryl-10 Stearate, Tocopherol

Stearic Acid

Squalane

Glyceryl Stearate

Cetyl Alcohol

Stearyl Alcohol

Palmitic Acid

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-5

Dunaliella Salina Extract

Panthenol

Hydroxyacetophenone

Sorbitan Oleate

Aluminum Starch Octenylsuccinate

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Phenoxyethanol

Boron Nitride

Tocopheryl Acetate

Isohexadecane

Chlorphenesin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Polysorbate 80

Carbomer

Sodium Lactate

Polysorbate 20

Citric Acid

Pantolactone

Sodium Benzoate

Potassium Sorbate

Water, Glycerin, Simmondsia Chinensis Seed Oil, Stearic Acid, Squalane, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Palmitic Acid, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Dunaliella Salina Extract, Panthenol, Sodium Hyaluronate, Hydroxyacetophenone, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, Butylene Glycol, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Tocopheryl Acetate, Isohexadecane, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Polysorbate 80, Carbomer, Sodium Lactate, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Pantolactone, Sodium Benzoate, Potassium Sorbate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Jojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.

Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.

Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.

Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).

Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.

Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fungal acne: The Malassezia yeast is known to metabolize fatty acids in the C11-24 range and jojoba's dominant fatty acid components fall into this range. This ingredient may not be fungal acne safe.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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