Skin science article
Beauty of Joseon Dynasty Cream (Old Formulation) Versus Anua Heartleaf 70 Intense Calming Cream
Beauty of Joseon Dynasty Cream (Old Formulation) Versus Anua Heartleaf 70 Intense Calming Cream This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin. This calming moisturizer is formulat
Beauty of Joseon Dynasty Cream (Old Formulation) Versus Anua Heartleaf 70 Intense Calming Cream
This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin.
This calming moisturizer is formulated around Panthenol and Ceramide NP to calm redness and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Butylene Glycol
Niacinamide
Dipentaerythrityl Hexa C5-9 Acid Esters
Sodium Hyaluronate
Xanthan Gum
Cyclopentasiloxane
Cyclohexasiloxane
Polyacrylate-13
Polyisobutene
Polysorbate 20
Hydrogenated Lecithin
C14-28 Alkyl Acid
Stearyl Alcohol
Behenyl Alcohol
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethicone
Adenosine
Glyceryl Stearate Se
Cetearyl Alcohol
Polyglyceryl-3 Methylglucose Distearate
Cetyl PEG/PPG-10/1 Dimethicone
Stearic Acid
Tocopheryl Acetate
Sodium Polyacrylate
Olea Europaea Fruit Oil
Helianthus Annuus Seed Oil
Centella Asiatica Extract
Hippophae Rhamnoides Oil
Argania Spinosa Kernel Oil
Butyrospermum Parkii Butter
Ceramide NP
Trehalose
Calendula Officinalis Flower Extract
Caprylhydroxamic Acid
1,2-Hexanediol
Raphanus Sativus Leaf Extract
Oryza Sativa Bran Extract
Cucurbitaceae Extract
Orchid Extract
Honey Extract
Panax Ginseng Root Extract
Carthamus Tinctorius Seed Oil
Phytosphingosine
Ceteareth-20
Glyceryl Citrate/Lactate/Linoleate/Oleate
Parfum
Water, Glycerin, Butylene Glycol, Niacinamide, Dipentaerythrityl Hexa C5-9 Acid Esters, Sodium Hyaluronate, Xanthan Gum, Cyclopentasiloxane, Cyclohexasiloxane, Polyacrylate-13, Polyisobutene, Polysorbate 20, Hydrogenated Lecithin, C14-28 Alkyl Acid, Stearyl Alcohol, Behenyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone, Adenosine, Glyceryl Stearate Se, Cetearyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Cetyl PEG/PPG-10/1 Dimethicone, Stearic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Olea Europaea Fruit Oil, Helianthus Annuus Seed Oil, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Argania Spinosa Kernel Oil, Butyrospermum Parkii Butter, Ceramide NP, Trehalose, Calendula Officinalis Flower Extract, Caprylhydroxamic Acid, 1,2-Hexanediol, Raphanus Sativus Leaf Extract, Oryza Sativa Bran Extract, Cucurbitaceae Extract, Orchid Extract, Honey Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Seed Oil, Phytosphingosine, Ceteareth-20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Parfum
Houttuynia Cordata Flower/Leaf/Stem Water
Caprylic/Capric Triglyceride
Hydrogenated Poly(C6-14 Olefin)
Hydrogenated Polydecene
Dicaprylyl Ether
Vinyldimethicone
Cetearyl Olivate
Vegetable Oil
Panthenol
Dipropylene Glycol
Sorbitan Olivate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Cetearyl Glucoside
Ethylhexylglycerin
Cholesterol
Tocopherol
Houttuynia Cordata Flower/Leaf/Stem Water, Cetearyl Alcohol, Glycerin, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Dicaprylyl Ether, Vinyldimethicone, Cetearyl Olivate, Vegetable Oil, Glyceryl Stearate Se, Panthenol, Hydrogenated Lecithin, Dipropylene Glycol, Behenyl Alcohol, Sorbitan Olivate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Cetearyl Glucoside, Ethylhexylglycerin, Cholesterol, Xanthan Gum, Adenosine, Ceramide NP, Tocopherol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).
Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.
Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.
In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.
As an emulsifier, Glyceryl Stearate Se prevents ingredients such as oil and water from separating. It is also a surfactant, meaning it helps cleanse the skin. Surfactants help gather oil, dirt, and other pollutants so they may be rinsed away easily.
Emollients help your skin stay smooth and soft. It does so by creating a film on top of the skin that helps trap moisture in.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.