Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Beauty of Joseon Dynasty Cream (Old Formulation) Versus BYOMA Moisturizing Gel-Cream

Beauty of Joseon Dynasty Cream (Old Formulation) Versus BYOMA Moisturizing Gel-Cream This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated a

Beauty of Joseon Dynasty Cream (Old Formulation) Versus BYOMA Moisturizing Gel-Cream

This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Niacinamide

Dipentaerythrityl Hexa C5-9 Acid Esters

Sodium Hyaluronate

Xanthan Gum

Cyclopentasiloxane

Cyclohexasiloxane

Polyacrylate-13

Polyisobutene

Polysorbate 20

Hydrogenated Lecithin

C14-28 Alkyl Acid

Stearyl Alcohol

Behenyl Alcohol

Dimethicone/Vinyl Dimethicone Crosspolymer

Dimethicone

Adenosine

Glyceryl Stearate Se

Cetearyl Alcohol

Polyglyceryl-3 Methylglucose Distearate

Cetyl PEG/PPG-10/1 Dimethicone

Stearic Acid

Tocopheryl Acetate

Sodium Polyacrylate

Olea Europaea Fruit Oil

Helianthus Annuus Seed Oil

Centella Asiatica Extract

Hippophae Rhamnoides Oil

Argania Spinosa Kernel Oil

Butyrospermum Parkii Butter

Ceramide NP

Trehalose

Calendula Officinalis Flower Extract

Caprylhydroxamic Acid

1,2-Hexanediol

Raphanus Sativus Leaf Extract

Oryza Sativa Bran Extract

Cucurbitaceae Extract

Orchid Extract

Honey Extract

Panax Ginseng Root Extract

Carthamus Tinctorius Seed Oil

Phytosphingosine

Ceteareth-20

Glyceryl Citrate/Lactate/Linoleate/Oleate

Parfum

Water, Glycerin, Butylene Glycol, Niacinamide, Dipentaerythrityl Hexa C5-9 Acid Esters, Sodium Hyaluronate, Xanthan Gum, Cyclopentasiloxane, Cyclohexasiloxane, Polyacrylate-13, Polyisobutene, Polysorbate 20, Hydrogenated Lecithin, C14-28 Alkyl Acid, Stearyl Alcohol, Behenyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone, Adenosine, Glyceryl Stearate Se, Cetearyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Cetyl PEG/PPG-10/1 Dimethicone, Stearic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Olea Europaea Fruit Oil, Helianthus Annuus Seed Oil, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Argania Spinosa Kernel Oil, Butyrospermum Parkii Butter, Ceramide NP, Trehalose, Calendula Officinalis Flower Extract, Caprylhydroxamic Acid, 1,2-Hexanediol, Raphanus Sativus Leaf Extract, Oryza Sativa Bran Extract, Cucurbitaceae Extract, Orchid Extract, Honey Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Seed Oil, Phytosphingosine, Ceteareth-20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Parfum

Caprylic/Capric Triglyceride

Pentaerythrityl Tetraethylhexanoate

Cholesterol

Camellia Sinensis Leaf Extract

Oleic Acid

Lactic Acid

Panthenol

Carbomer

Tromethamine

Caprylyl Glycol

Hydroxyacetophenone

Water, Glycerin, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraethylhexanoate, Polyglyceryl-3 Methylglucose Distearate, Niacinamide, Ceramide NP, Cholesterol, Phytosphingosine, Camellia Sinensis Leaf Extract, Stearic Acid, Oleic Acid, Lactic Acid, Hydrogenated Lecithin, Cetearyl Alcohol, Panthenol, Carbomer, Xanthan Gum, Tromethamine, 1,2-Hexanediol, Caprylyl Glycol, Hydroxyacetophenone, Caprylhydroxamic Acid

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Caprylhydroxamic Acid is a chelating agent that helps cosmetics stay fresh, stable, and consistent over time.

Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product. It also helps prevent the growth of unwanted microbes in products that contain water.

Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Phytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.

Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.

Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.

Fun fact: Phytosphingosine is abundant in plants and fungi.

More ingredients that help boost collagen in skin:

Polyglyceryl-3 Methylglucose Distearate is a plant-derived emulsifier whose only job is to keep the oily and watery parts of a formula blended so it doesn't separate into layers.

It's compatible with a wide-range of active ingredients and especially good at making emulsions survive heat/freeze cycles.

Typical use concentrations range from 2-3% and it works across a pH of 4.5-8.5.

This ingredient has been found safe to use in cosmetics and has a low irritation profile.

Because it's build on stearic acid, it may not be fungal acne safe. Stearic acid is a C18 fatty acid that falls within the range (C11-24) that Malassezia can feed on.

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Centella Asiatica Extract
  2. 023-O-Ethyl Ascorbic Acid
  3. 03Glycerin
  4. 04Propanediol
  5. 05Betaine
  6. 06Dicaprylyl Carbonate
  7. 07Methyl Trimethicone
  8. 08Cetyl Ethylhexanoate
  9. 09Panthenol
  10. 10Laminaria Japonica Extract
  11. 11Eclipta Prostrata Leaf Extract
  12. 12Phellodendron Amurense Bark Extract
  13. 13Citrus Unshiu Peel Extract
  14. 14Brassica Oleracea Acephala Leaf Extract
  15. 15Hydrolyzed Gardenia Florida Extract
  16. 16Hydrogenated Lecithin
  17. 17Cetearyl Alcohol
  18. 18Water
  19. 19Dimethicone/Vinyl Dimethicone Crosspolymer
  20. 20Silica
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side