Beauty of Joseon Glow Serum: Propolis + Niacinamide Versus AMPLE:N Acne Shot Ampoule

Beauty of Joseon Glow Serum: Propolis + Niacinamide Versus AMPLE:N Acne Shot Ampoule

This acne serum is formulated around Propolis Extract and Niacinamide to clear breakouts and brighten dull-looking skin.

This acne ampoule is formulated around Propolis Extract and Dipotassium Glycyrrhizate to clear breakouts and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Propolis Extract

Dipropylene Glycol

Glycerin

Butylene Glycol

Water

Niacinamide

1,2-Hexanediol

Melia Azadirachta Flower Extract

Melia Azadirachta Leaf Extract

Sodium Hyaluronate

Curcuma Longa Root Extract

Ocimum Sanctum Leaf Extract

Theobroma Cacao Seed Extract

Melaleuca Alternifolia Leaf Extract

Centella Asiatica Extract

Corallina Officinalis Extract

Lotus Corniculatus Seed Extract

Calophyllum Inophyllum Seed Oil

Betaine Salicylate

Sodium Polyacryloyldimethyl Taurate

Tromethamine

Polyglyceryl-10 Laurate

Caprylyl Glycol

Ethylhexylglycerin

Dextrin

Pentylene Glycol

Octanediol

Tocopherol

Xanthan Gum

Carbomer

Propolis Extract, Dipropylene Glycol, Glycerin, Butylene Glycol, Water, Niacinamide, 1,2-Hexanediol, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Sodium Hyaluronate, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Theobroma Cacao Seed Extract, Melaleuca Alternifolia Leaf Extract, Centella Asiatica Extract, Corallina Officinalis Extract, Lotus Corniculatus Seed Extract, Calophyllum Inophyllum Seed Oil, Betaine Salicylate, Sodium Polyacryloyldimethyl Taurate, Tromethamine, Polyglyceryl-10 Laurate, Caprylyl Glycol, Ethylhexylglycerin, Dextrin, Pentylene Glycol, Octanediol, Tocopherol, Xanthan Gum, Carbomer

Propolis Extract 45%

Propanediol

Octyldodeceth-16

Chamomilla Recutita Flower Extract

Glycyrrhiza Glabra Root Extract

Arginine

Gaultheria Procumbens Leaf Extract

Glycine Soja Sprout Extract

Dipotassium Glycyrrhizate

Madecassoside

Capryloyl Salicylic Acid

Adenosine

Disodium EDTA

Sodium Metaphosphate

Melaleuca Alternifolia Leaf Oil

Hydrolyzed Chitosan

Propolis Extract 45%, Water, Butylene Glycol, Propanediol, Octyldodeceth-16, 1,2-Hexanediol, Chamomilla Recutita Flower Extract, Glycyrrhiza Glabra Root Extract, Centella Asiatica Extract, Arginine, Gaultheria Procumbens Leaf Extract, Glycine Soja Sprout Extract, Dipotassium Glycyrrhizate, Madecassoside, Capryloyl Salicylic Acid, Adenosine, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Curcuma Longa Root Extract, Disodium EDTA, Sodium Metaphosphate, Melaleuca Alternifolia Leaf Oil, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Hydrolyzed Chitosan

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.

That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Corallina Officinalis Extract is from the red seaweed, Corallina Officinalis. This seaweed is found all over the world but is most common in the rocky shores of Great Britain and Ireland.

Corallina Officinalis Extract contains antioxidant and emollient properties.

Extracted polysaccharides, galactose and xylose, in red algae showed antioxidant activity. Antioxidants help with anti-aging by neutralizing free-radical molecules. Free-radical molecules may damage your skin cells and DNA. Galactose is also a PHA.

Corallina Officinalis is structurally similar to coral due to its high calcium content.

Curcuma Longa Root Extract comes from the rhizome (underground stem) of the turmeric plant.

While the official EU Cosing Database lists this ingredient as a fragrance, it actually does more than give products a scent.

This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.

Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.

One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.

At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.

Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.

Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.

Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

The flowers of this tree are lilac colored.

This ingredient is also known as neem leaf extract. It contains natural compounds like nimbidin, quercetin, and other polyphenols that give it antibacterial, antifungal, and anti-inflammatory activity.

Lab studies have shown neem leaf extract can inhibit acne-related bacteria and help calm skin. Animal studies on wound gels using 1-3% neem leaf extract found it sped up healing without causing irritation.

A wound-healing study testing gels with the extract at 1%, 2%, and 3% concentrations and found none of them irritated the skin.

Most commercial products also use it in a similar low range (typically under 5%).

Allergy-wise, there are some case reports on neem oil causing allergic contact dermatitis so people with plant/botanical sensitivities may want to patch test first.

Ocimum Sanctum Leaf Extract comes from the Holy Basil plant. Holy Basil is native to India.

Holy Basil is rich in antioxidants due to its high romarinic acid, ferulic acid, and rutin content. This gives it skin brightening and soothing properties.

While Holy Basil has many claims to help fight acne, more research is needed.

One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.

Propolis Extract is a natural ingredient derived from propolis (also known as bee glue). Bees make propolis by mixing their saliva and beeswax with resins collected from tree buds and plants.

This ingredient is packed with bioactive compounds like flavonoids, phenolic acids, and amino acids that give it antioxidant and anti-inflammatory properties.

Research shows it can help:

It also pairs nicely with hydrating ingredients like niacinamide and ceramides.

Just so you know, Propolis Extract is recognized as a contact allergen. In patch tests done in the EU, roughly 1-6% of patients react to it. Be sure to steer clear of this ingredient if you have a known allergy to bee products.

Since it is an animal-derived product, this ingredient is not considered vegan. For vegan alternatives, check out Galactomyces Ferment Filtrate or Centella Asiatica Extract.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons