Skin science article
Beauty of Joseon Glow Serum: Propolis + Niacinamide Versus Make p:rem End Pore Vegetinol Tightening Serum
Beauty of Joseon Glow Serum: Propolis + Niacinamide Versus Make p:rem End Pore Vegetinol Tightening Serum This acne serum is formulated around Propolis Extract and Niacinamide to clear breakouts and brighten dull-looking skin. This pore-care serum is formulate
Beauty of Joseon Glow Serum: Propolis + Niacinamide Versus Make p:rem End Pore Vegetinol Tightening Serum
This acne serum is formulated around Propolis Extract and Niacinamide to clear breakouts and brighten dull-looking skin.
This pore-care serum is formulated around Niacinamide and Bakuchiol to refine the look of pores and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Propolis Extract
Dipropylene Glycol
Glycerin
Butylene Glycol
Water
Niacinamide
1,2-Hexanediol
Melia Azadirachta Flower Extract
Melia Azadirachta Leaf Extract
Sodium Hyaluronate
Curcuma Longa Root Extract
Ocimum Sanctum Leaf Extract
Theobroma Cacao Seed Extract
Melaleuca Alternifolia Leaf Extract
Centella Asiatica Extract
Corallina Officinalis Extract
Lotus Corniculatus Seed Extract
Calophyllum Inophyllum Seed Oil
Betaine Salicylate
Sodium Polyacryloyldimethyl Taurate
Tromethamine
Polyglyceryl-10 Laurate
Caprylyl Glycol
Ethylhexylglycerin
Dextrin
Pentylene Glycol
Octanediol
Tocopherol
Xanthan Gum
Carbomer
Propolis Extract, Dipropylene Glycol, Glycerin, Butylene Glycol, Water, Niacinamide, 1,2-Hexanediol, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Sodium Hyaluronate, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Theobroma Cacao Seed Extract, Melaleuca Alternifolia Leaf Extract, Centella Asiatica Extract, Corallina Officinalis Extract, Lotus Corniculatus Seed Extract, Calophyllum Inophyllum Seed Oil, Betaine Salicylate, Sodium Polyacryloyldimethyl Taurate, Tromethamine, Polyglyceryl-10 Laurate, Caprylyl Glycol, Ethylhexylglycerin, Dextrin, Pentylene Glycol, Octanediol, Tocopherol, Xanthan Gum, Carbomer
Methylpropanediol
Propanediol
Collagen Extract
Theobroma Cacao Extract
Soluble Collagen
Bakuchiol
Glyceryl Polymethacrylate
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Caffeine
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Diethoxyethyl Succinate
Hydrogenated Lecithin
Hydrogenated Polyisobutene
Panthenol
Allantoin
Adenosine
Dipotassium Glycyrrhizate
Gluconolactone
Citric Acid
Sodium Phytate
Beta-Glucan
Cyanocobalamin
Eucalyptus Globulus Leaf Oil
Amyris Balsamifera Bark Oil
Juniperus Mexicana Oil
Mentha Viridis Leaf Oil
Lavandula Angustifolia Oil
Myristica Fragrans Kernel Oil
Citrus Aurantium Bergamia Fruit Oil
Water, Methylpropanediol, Propanediol, 1,2-Hexanediol, Butylene Glycol, Niacinamide, Glycerin, Collagen Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Ocimum Sanctum Leaf Extract, Theobroma Cacao Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Soluble Collagen, Pentylene Glycol, Bakuchiol, Glyceryl Polymethacrylate, Polyglyceryl-10 Laurate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caffeine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Diethoxyethyl Succinate, Hydrogenated Lecithin, Hydrogenated Polyisobutene, Panthenol, Tromethamine, Ethylhexylglycerin, Allantoin, Adenosine, Dipotassium Glycyrrhizate, Gluconolactone, Citric Acid, Sodium Phytate, Dextrin, Beta-Glucan, Tocopherol, Cyanocobalamin, Eucalyptus Globulus Leaf Oil, Amyris Balsamifera Bark Oil, Juniperus Mexicana Oil, Mentha Viridis Leaf Oil, Lavandula Angustifolia Oil, Myristica Fragrans Kernel Oil, Citrus Aurantium Bergamia Fruit Oil
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Corallina Officinalis Extract is from the red seaweed, Corallina Officinalis. This seaweed is found all over the world but is most common in the rocky shores of Great Britain and Ireland.
Corallina Officinalis Extract contains antioxidant and emollient properties.
Extracted polysaccharides, galactose and xylose, in red algae showed antioxidant activity. Antioxidants help with anti-aging by neutralizing free-radical molecules. Free-radical molecules may damage your skin cells and DNA. Galactose is also a PHA.
Corallina Officinalis is structurally similar to coral due to its high calcium content.
Curcuma Longa Root Extract comes from the rhizome (underground stem) of the turmeric plant.
While the official EU Cosing Database lists this ingredient as a fragrance, it actually does more than give products a scent.
This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.
Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.
One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.
At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.
Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.
Dextrin is a starch-derived polysaccharide. It's made by partially breaking down corn, potato, or other plant starches.
Think of it as "half-processed" starch; it's less complex than the original but not fully broken down into sugar like maltodextrin.
In cosmetics, it mainly functions as a bulking agent, viscosity controller, binder, and absorbent. It helps thicken products, stabilize powders, and get certain textures a less "wet" feel.
This ingredient has a pretty solid safety profile; it's recognized as a safe food additive and its large molecular size means it doesn't meaningfully penetrate skin.
Human repeat insult patch tests using a rinse-off facial product containing 42.69% dextrin found no skin irritation or sensitization in 54 subjects.
Typical real-world usage is much lower: usually under 1% as a texture modifier and up to 40% in masks (rinse off products use less).
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.
Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
The flowers of this tree are lilac colored.
This ingredient is also known as neem leaf extract. It contains natural compounds like nimbidin, quercetin, and other polyphenols that give it antibacterial, antifungal, and anti-inflammatory activity.
Lab studies have shown neem leaf extract can inhibit acne-related bacteria and help calm skin. Animal studies on wound gels using 1-3% neem leaf extract found it sped up healing without causing irritation.
A wound-healing study testing gels with the extract at 1%, 2%, and 3% concentrations and found none of them irritated the skin.
Most commercial products also use it in a similar low range (typically under 5%).
Allergy-wise, there are some case reports on neem oil causing allergic contact dermatitis so people with plant/botanical sensitivities may want to patch test first.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Ocimum Sanctum Leaf Extract comes from the Holy Basil plant. Holy Basil is native to India.
Holy Basil is rich in antioxidants due to its high romarinic acid, ferulic acid, and rutin content. This gives it skin brightening and soothing properties.
While Holy Basil has many claims to help fight acne, more research is needed.
One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier.
It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.
On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).
Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.
This ingredient is an ester of lauric acid and Polyglycerin-10.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!