Skin science article
Beauty of Joseon Red Bean Water Gel Versus Dear, Klairs Midnight Blue Calming Cream
Beauty of Joseon Red Bean Water Gel Versus Dear, Klairs Midnight Blue Calming Cream This calming moisturizer is formulated around Panthenol and Allantoin to calm redness and hydrate skin. This calming moisturizer is formulated around Centella Asiatica Extract
Beauty of Joseon Red Bean Water Gel Versus Dear, Klairs Midnight Blue Calming Cream
This calming moisturizer is formulated around Panthenol and Allantoin to calm redness and hydrate skin.
This calming moisturizer is formulated around Centella Asiatica Extract and Ceramide NP to calm redness and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Glycerin
1,2-Hexanediol
Methyl Trimethicone
Phaseolus Angularis Seed Extract
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Tromethamine
Glyceryl Glucoside
C12-14 Alketh-12
Maltodextrin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethicone Crosspolymer
Ethylhexylglycerin
Betaine
Panthenol
Allantoin
Dipotassium Glycyrrhizate
Polyquaternium-51
Xanthan Gum
Disodium EDTA
Glyceryl Acrylate/Acrylic Acid Copolymer
Dioscorea Japonica Root Extract
Glucose
Sodium Citrate
Beta-Glucan
Hydrolyzed Corn Starch
Citric Acid
Sucrose
Magnesium Ascorbyl Phosphate
Caprylyl Glycol
Helianthus Annuus Seed Oil
Tocopherol
Cyanocobalamin
Glycine
Serine
Glutamic Acid
Aspartic Acid
Leucine
Acetyl Hexapeptide-8
Alanine
Lysine
Arginine
Tyrosine
Phenylalanine
Proline
Threonine
Valine
Isoleucine
Histidine
Cysteine
Methionine
Phosphoric Acid
Ascorbic Acid
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Methyl Trimethicone, Phaseolus Angularis Seed Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Glucoside, C12-14 Alketh-12, Maltodextrin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone Crosspolymer, Ethylhexylglycerin, Betaine, Panthenol, Allantoin, Dipotassium Glycyrrhizate, Polyquaternium-51, Xanthan Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Dioscorea Japonica Root Extract, Glucose, Sodium Citrate, Beta-Glucan, Hydrolyzed Corn Starch, Citric Acid, Sucrose, Magnesium Ascorbyl Phosphate, Caprylyl Glycol, Helianthus Annuus Seed Oil, Tocopherol, Cyanocobalamin, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Acetyl Hexapeptide-8, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Cysteine, Methionine, Phosphoric Acid, Ascorbic Acid, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1
Cetyl Ethylhexanoate
Sodium Hyaluronate
Caprylic/Capric Triglyceride
Centella Asiatica Extract
Sorbitan Stearate
Cetyl Alcohol
Butyrospermum Parkii Butter
Argania Spinosa Kernel Oil
Simmondsia Chinensis Seed Oil
Sorbitan Sesquioleate
Glyceryl Stearate
Stearic Acid
Portulaca Oleracea Extract
Anthemis Nobilis Flower Extract
Ceramide NP
Polysorbate 60
Candelilla Cera
Chlorphenesin
Tocopheryl Acetate
Morus Alba Root Extract
Brassica Oleracea Italica Extract
Guaiazulene
Lecithin
Acetyl Glutamine
Sh-Polypeptide-9
Sh-Polypeptide-11
Bacillus/Folic Acid/Soybean Ferment Extract
Water, Cetyl Ethylhexanoate, Butylene Glycol, Glycerin, Sodium Hyaluronate, Caprylic/Capric Triglyceride, Centella Asiatica Extract, Sorbitan Stearate, Cetyl Alcohol, Butyrospermum Parkii Butter, Argania Spinosa Kernel Oil, Simmondsia Chinensis Seed Oil, Sorbitan Sesquioleate, Glyceryl Stearate, Stearic Acid, Portulaca Oleracea Extract, Anthemis Nobilis Flower Extract, Ceramide NP, Polysorbate 60, Candelilla Cera, Chlorphenesin, Tocopheryl Acetate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Morus Alba Root Extract, Tromethamine, Brassica Oleracea Italica Extract, Guaiazulene, Acetyl Hexapeptide-8, Lecithin, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Bacillus/Folic Acid/Soybean Ferment Extract, Caprylyl Glycol, 1,2-Hexanediol
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
This peptide has similar properties to Sh-Oligopeptide-1.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.