Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Beauty Pie Happy Face 10% Azelaic Acid Skin-Clearing Gel-Cream Versus Paula's Choice 10% Azelaic Acid Booster

Beauty Pie Happy Face 10% Azelaic Acid Skin-Clearing Gel-Cream Versus Paula's Choice 10% Azelaic Acid Booster This calming treatment is formulated around Azelaic Acid and Niacinamide to calm redness and clear breakouts. This calming treatment is formulated aro

Beauty Pie Happy Face 10% Azelaic Acid Skin-Clearing Gel-Cream Versus Paula's Choice 10% Azelaic Acid Booster

This calming treatment is formulated around Azelaic Acid and Niacinamide to calm redness and clear breakouts.

This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Butylene Glycol

Azelaic Acid

Glycerin

Triethylhexanoin

Dipropylene Glycol

Dimethicone/Vinyl Dimethicone Crosspolymer

Pentylene Glycol

Niacinamide

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polysorbate 60

Squalane

Phenoxyethanol

Tocopherol

Disodium EDTA

Rosa Multiflora Fruit Extract

Madecassoside

Porphyra Yezoensis Extract

Yeast Extract

Oryza Sativa Lees Extract

Asiaticoside

Asiatic Acid

Madecassic Acid

Prunus Lannesiana Flower Extract

Water, Dimethicone, Butylene Glycol, Azelaic Acid, Glycerin, Triethylhexanoin, Dipropylene Glycol, Dimethicone/Vinyl Dimethicone Crosspolymer, Pentylene Glycol, Niacinamide, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Squalane, Phenoxyethanol, Tocopherol, Disodium EDTA, Rosa Multiflora Fruit Extract, Madecassoside, Porphyra Yezoensis Extract, Yeast Extract, Oryza Sativa Lees Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Prunus Lannesiana Flower Extract

C12-15 Alkyl Benzoate

Caprylic/Capric Triglyceride

Methyl Glucose Sesquistearate

Cetearyl Alcohol

Glyceryl Stearate

Salicylic Acid

Adenosine

Glycyrrhiza Glabra Root Extract

Boerhavia Diffusa Root Extract

Allantoin

Bisabolol

Cyclopentasiloxane

Xanthan Gum

Sclerotium Gum

Propanediol

Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes it special?

OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.

Here's what each tier does best:

Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.

Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Hydrogenated Castor Oil
  3. 03Glycerin
  4. 04Vitis Vinifera Seed Oil
  5. 05Cocos Nucifera Oil
  6. 06Caprylic/Capric Triglyceride
  7. 07Glycolic Acid
  8. 08Lactic Acid
  9. 09Cetearyl Alcohol
  10. 10Stearyl Alcohol
  11. 11Sodium Hydroxide
  12. 12Propanediol
  13. 13Cetearyl Glucoside
  14. 14Betaine
  15. 15Oryza Sativa Bran Extract
  16. 16Panthenol
  17. 17Chlorphenesin
  18. 18Helianthus Annuus Extract
  19. 19Bisabolol
  20. 20Simmondsia Chinensis Seed Oil
Source · skinsort.com
02

Product index

Related product references

Product

Paula's Choice Omega+ Complex Serum

Paula's Choice Omega+ Complex Serum Paula's Choice Omega+ Complex Serum ingredients explained: Water, Glycerin (Skin-Replenishing Ingredient), Diheptyl Succinate (Emollient), Candelilla/Joj…

Source: incidecoder.comView reference →

Product

Paula's Choice The Unscrub

Paula's Choice The Unscrub Paula's Choice The Unscrub ingredients explained: Aqua (Water), Jojoba Esters (Cleansing Beads), Caprylic/Capric Triglyceride (Skin-Replenishing), Glycerin (Skin …

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side