Skin science article
Best Peptides for Anti-Aging & Longevity
Best Peptides for Anti-Aging & Longevity The peptides most studied for anti-aging and longevity include Epithalon (researched for telomerase and circadian pathways), NAD+ and SS-31 for mitochondrial function, MOTS-c for metabolic aging, and Thymalin for immune
Best Peptides for Anti-Aging & Longevity
The peptides most studied for anti-aging and longevity include Epithalon (researched for telomerase and circadian pathways), NAD+ and SS-31 for mitochondrial function, MOTS-c for metabolic aging, and Thymalin for immune aging. Most evidence is preclinical.
Longevity peptides target the biology of aging rather than a single symptom. Epithalon is the most-discussed, studied for telomerase activity and circadian/pineal regulation. A mitochondrial group — NAD+, SS-31, MOTS-c, Humanin — is researched for cellular energy and metabolic aging. Thymalin and related thymic peptides are studied for immune aging. This is among the most preliminary categories: most data is animal or in-vitro, graded below.
Most-studied compounds for anti-aging & longevity
Each links to a full research protocol with reconstitution steps, research dose ranges reported in the literature, and an honest evidence grade. Ranked roughly by depth of supporting research.
Epithalon
A tetrapeptide researched for telomerase activity and pineal/circadian regulation — the most-studied longevity peptide, mostly in animal models.
NAD+
Researched for cellular energy metabolism and DNA-repair pathways central to aging biology.
SS-31
Elamipretide — a mitochondria-targeted peptide studied for protecting cardiolipin and cellular energy production.
MOTS-c
A mitochondrial-derived peptide studied for metabolic regulation and exercise-mimetic pathways.
Humanin
A mitochondrial-derived peptide researched for cytoprotection and metabolic-aging signaling.
Thymalin
A thymic peptide studied for restoring immune balance associated with aging.
FOXO4-DRI
A research peptide studied for selectively clearing senescent ("zombie") cells in preclinical models.
Pinealon
A short peptide researched for neuronal protection and circadian/aging pathways.
Sourcing these compounds for research
Researchers studying the molecules above source cGMP-tested material from our official sponsor, LiveWell Peptides. All compounds are sold strictly for laboratory research use.
Preferred vendor. For research use only. Not for human consumption. Not medical advice.
Plan your research
Free tools to take any compound above from vial to a documented protocol.