Skin science article
Bioderma Sensibio Defensive Active Soothing Cream Versus COSRX The 6 Peptide Skin Booster Serum
Bioderma Sensibio Defensive Active Soothing Cream Versus COSRX The 6 Peptide Skin Booster Serum This barrier-repair moisturizer is formulated around Squalane and Carnosine to strengthen the skin barrier. This anti-aging serum is formulated around Niacinamide a
Bioderma Sensibio Defensive Active Soothing Cream Versus COSRX The 6 Peptide Skin Booster Serum
This barrier-repair moisturizer is formulated around Squalane and Carnosine to strengthen the skin barrier.
This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dicaprylyl Ether
Propylheptyl Caprylate
Butylene Glycol
Glyceryl Stearate Citrate
Glycol Palmitate
Squalane
Sucrose Stearate
Mangifera Indica Seed Butter
Pentylene Glycol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Caprylyl Glycol
Carnosine
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Mannitol
Xylitol
Tocopherol
Salvia Miltiorrhiza Flower/Leaf/Root Extract
Rhamnose
Glycine Soja Oil
Polysorbate 60
Sorbitan Isostearate
Palmitoyl Tetrapeptide-10
Water, Glycerin, Dicaprylyl Ether, Propylheptyl Caprylate, Butylene Glycol, Glyceryl Stearate Citrate, Glycol Palmitate, Squalane, Sucrose Stearate, Mangifera Indica Seed Butter, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Carnosine, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Mannitol, Xylitol, Tocopherol, Salvia Miltiorrhiza Flower/Leaf/Root Extract, Rhamnose, Glycine Soja Oil, Polysorbate 60, Sorbitan Isostearate, Palmitoyl Tetrapeptide-10
Dipropylene Glycol
1,2-Hexanediol
Niacinamide
Acetyl Hexapeptide-8
Copper Tripeptide-1
Sh-Polypeptide-121
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Oligopeptide-68
Palmitoyl Tripeptide-8
Allantoin
Sodium Hyaluronate
Acetyl Glucosamine
Serine
Alanine
Glycine
Threonine
Arginine
Proline
Betaine
Sodium PCA
Sodium Lactate
PCA
Glutamic Acid
Lysine Hcl
Dextran
Hydrogenated Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Polyacrylate Crosspolymer-6
Xanthan Gum
Ethylhexylglycerin
Adenosine
Polyquaternium-51
Disodium EDTA
Citric Acid
T-Butyl Alcohol
Potassium Sorbate
Sodium Oleate
Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Acetyl Hexapeptide-8, Copper Tripeptide-1, Sh-Polypeptide-121, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-68, Palmitoyl Tripeptide-8, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Serine, Alanine, Glycine, Threonine, Arginine, Proline, Betaine, Sodium PCA, Sodium Lactate, PCA, Glutamic Acid, Lysine Hcl, Tocopherol, Dextran, Glycine Soja Oil, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium EDTA, Citric Acid, Caprylyl Glycol, T-Butyl Alcohol, Potassium Sorbate, Sodium Oleate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glycine Soja Oil is a plant-derived oil from soybean seeds. Like other oils, it is rich in essential fatty acids (mostly linoleic and oleic) that support skin hydration and barrier function.
The fatty acids are able to integrate into the lipid matrix of the stratum corneum to help soften skin and reduce water loss.
On top of that, soybean oil is rich in vitamins like vitamin E, a potent antioxidant.
Research on soybean's active components also point to anti-inflammatory, collagen-stimulating, antioxidant activity, and protection against UV-induced oxidative damage.
Most of this research applies to the broader soybean plant and not just the oil fraction alone.
This ingredient may not be fungal acne safe due to the oleic acid content.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!