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BioNike Aknet Azerose Intensive Care Versus Paula's Choice Clinical Niacinamide 20% Treatment

BioNike Aknet Azerose Intensive Care Versus Paula's Choice Clinical Niacinamide 20% Treatment This acne treatment is formulated around Glycolic Acid and Niacinamide to clear breakouts and calm redness. This pore-care treatment is formulated around Niacinamide

BioNike Aknet Azerose Intensive Care Versus Paula's Choice Clinical Niacinamide 20% Treatment

This acne treatment is formulated around Glycolic Acid and Niacinamide to clear breakouts and calm redness.

This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycolic Acid

Dipotassium Azelate

Niacinamide

Butylene Glycol

Pentylene Glycol

Myrtus Communis Leaf Water

Magnesium Aluminum Silicate

Canola Oil

Succinic Acid

Sodium Hydroxide

4-T-Butylcyclohexanol

Xanthan Gum

Tocopheryl Acetate

Aminobutyric Acid

Sclerotium Gum

Lecithin

Pullulan

Caprylyl Glycol

Potassium Cetyl Phosphate

Silica

Lactic Acid

Propanediol

Citric Acid

Trisodium Ethylenediamine Disuccinate

Water, Glycolic Acid, Dipotassium Azelate, Niacinamide, Butylene Glycol, Pentylene Glycol, Myrtus Communis Leaf Water, Magnesium Aluminum Silicate, Canola Oil, Succinic Acid, Sodium Hydroxide, 4-T-Butylcyclohexanol, Xanthan Gum, Tocopheryl Acetate, Aminobutyric Acid, Sclerotium Gum, Lecithin, Pullulan, Caprylyl Glycol, Potassium Cetyl Phosphate, Silica, Lactic Acid, Propanediol, Citric Acid, Trisodium Ethylenediamine Disuccinate

Niacinamide 20%

Glycerin

Acetyl Glucosamine

Ascorbyl Glucoside

Glycyrrhiza Glabra Root Extract

Spiraea Ulmaria Extract

Portulaca Oleracea Extract

Camellia Japonica Flower Extract

Epigallocatechin Gallate

Boerhavia Diffusa Root Extract

Camellia Sinensis Leaf Extract

Allantoin

Panthenol

Sodium Phytate

Phenoxyethanol

Ethylhexylglycerin

Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Pullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.

According to a manufacturer, this ingredient's ability to easily dissolves makes it a great carrier for active ingredients.

Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.

Pullulan is stable over a broad-range of pH.

Sclerotium Gum is a natural sugar-based fiber made by fermenting a fungus called Sclerotium rolfsii. It's often used as the plant-friendly alternative for synthetic thickeners like carbomer.

In skincare, it works as a thickener, gel former, and stabilizer that keeps heavy ingredients suspended so a product does not separate.

It is non-ionic and forms a triple helix in solution. This is just a fancy way of saying it builds a smooth, cushiony, and non-sticky gel that feels silkier than many other gums.

Another perk of this ingredient is that it is very sturdy and holds up across a wide pH range (~2-11). It's also good at resisting heat and hydrolysis.

Since it holds water at the skin surface, it can provide some light hydration as well.

Typical use levels are around 0.25-2%; formulators usually use 0.2-0.5% to thicken lotions and up to 2% for a firmer gel base.

This ingredient has been found safe in cosmetics with no meaningful evidence of skin sensitization.

Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.

Though it has exfoliant properties, the function of silica varies depending on the product.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
  7. 07Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
  8. 08This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
  9. 09A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
  10. 10Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
  11. 11Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
  12. 12Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
  13. 13Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
  14. 14This ingredient mainly works behind the scenes and helps with:
  15. 15On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
  16. 16One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too st…
  17. 17Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
  18. 18You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
  19. 19Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  20. 20Topically, glycerin does several things at once:
Source · skinsort.com
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Product index

Related product references

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Comparison edit

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