Biossance Squalane + Copper Peptide Rapid Plumping Serum Versus Hanskin Collagen Peptide Eye Cream

Biossance Squalane + Copper Peptide Rapid Plumping Serum Versus Hanskin Collagen Peptide Eye Cream

This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Collagen Extract and Niacinamide to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Propanediol

Squalane

Sodium Hyaluronate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Copper Tripeptide-1

Acmella Oleracea Extract

Ectoin

Tetrapeptide-30

Palmitoyl Hexapeptide-52

Copper PCA

Panthenol

Sodium Polyglutamate

Camellia Sinensis Leaf Extract

Aloe Barbadensis Flower Extract

Passiflora Incarnata Flower Extract

Melia Azadirachta Leaf Extract

Solanum Melongena Fruit Extract

Curcuma Longa Root Extract

Ocimum Basilicum Flower/Leaf Extract

Coccinia Indica Fruit Extract

Melia Azadirachta Flower Extract

Ocimum Sanctum Leaf Extract

Corallina Officinalis Extract

Polyacrylate Crosspolymer-6

Acacia Senegal Gum

Xanthan Gum

Phenoxyethanol

Ethylhexylglycerin

Citric Acid

Caprylyl Glycol

Water, Glycerin, Propanediol, Squalane, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Copper Tripeptide-1, Acmella Oleracea Extract, Ectoin, Tetrapeptide-30, Palmitoyl Hexapeptide-52, Copper PCA, Panthenol, Sodium Polyglutamate, Camellia Sinensis Leaf Extract, Aloe Barbadensis Flower Extract, Passiflora Incarnata Flower Extract, Melia Azadirachta Leaf Extract, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Caprylyl Glycol

Collagen Extract

Vinyldimethicone

Glyceryl Stearate

Niacinamide

Pentaerythrityl Tetraethylhexanoate

Butylene Glycol

Butyrospermum Parkii Butter

Cetearyl Alcohol

Dipentaerythrityl Hexa C5-9 Acid Esters

Adenosine

Sodium Acetylated Hyaluronate

Hydrolyzed Hyaluronic Acid

Hydroxypropyltrimonium Hyaluronate

Sodium Hyaluronate Crosspolymer

Hyaluronic Acid

Potassium Hyaluronate

Hydrolyzed Elastin

Hydrolyzed Collagen

Acetyl Hexapeptide-8

Oligopeptide-29

Oligopeptide-32

Palmitoyl Pentapeptide-4

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-5

C14-22 Alcohols

C12-20 Alkyl Glucoside

Octapeptide-7

Sh-Decapeptide-7

Sh-Octapeptide-4

Sh-Oligopeptide-9

Sh-Pentapeptide-19

Pentapeptide-18

Acetyl Tetrapeptide-5

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-22

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Polyglyceryl-2 Stearate

Stearyl Alcohol

Sodium Polyacrylate

Pentylene Glycol

Cocos Nucifera Fruit Extract

Pinus Sylvestris Leaf Extract

Octyldodecanol

Caprylic/Capric Triglyceride

Hydrogenated Lecithin

Phytosteryl/Octyldodecyl Lauroyl Glutamate

1,2-Hexanediol

Ceramide NP

Arginine

Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate

Allantoin

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Chlorphenesin

Disodium EDTA

Collagen Extract, Vinyldimethicone, Glyceryl Stearate, Niacinamide, Pentaerythrityl Tetraethylhexanoate, Butylene Glycol, Glycerin, Butyrospermum Parkii Butter, Cetearyl Alcohol, Dipentaerythrityl Hexa C5-9 Acid Esters, Adenosine, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Potassium Hyaluronate, Hydrolyzed Elastin, Hydrolyzed Collagen, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, C14-22 Alcohols, C12-20 Alkyl Glucoside, Octapeptide-7, Sh-Decapeptide-7, Sh-Octapeptide-4, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Pentapeptide-18, Acetyl Tetrapeptide-5, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Polyglyceryl-2 Stearate, Stearyl Alcohol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Sodium Polyacrylate, Pentylene Glycol, Cocos Nucifera Fruit Extract, Pinus Sylvestris Leaf Extract, Panthenol, Water, Octyldodecanol, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Phytosteryl/Octyldodecyl Lauroyl Glutamate, 1,2-Hexanediol, Ceramide NP, Ethylhexylglycerin, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Allantoin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Caprylyl Glycol, Chlorphenesin, Disodium EDTA

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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