Biossance Squalane + Copper Peptide Rapid Plumping Serum Versus Medik8 Bakuchiol Peptides

Biossance Squalane + Copper Peptide Rapid Plumping Serum Versus Medik8 Bakuchiol Peptides

This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.

This anti-aging serum is formulated around Bakuchiol and Centella Asiatica Leaf Extract to soften the look of wrinkles and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Propanediol

Squalane

Sodium Hyaluronate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Copper Tripeptide-1

Acmella Oleracea Extract

Ectoin

Tetrapeptide-30

Palmitoyl Hexapeptide-52

Copper PCA

Panthenol

Sodium Polyglutamate

Camellia Sinensis Leaf Extract

Aloe Barbadensis Flower Extract

Passiflora Incarnata Flower Extract

Melia Azadirachta Leaf Extract

Solanum Melongena Fruit Extract

Curcuma Longa Root Extract

Ocimum Basilicum Flower/Leaf Extract

Coccinia Indica Fruit Extract

Melia Azadirachta Flower Extract

Ocimum Sanctum Leaf Extract

Corallina Officinalis Extract

Polyacrylate Crosspolymer-6

Acacia Senegal Gum

Xanthan Gum

Phenoxyethanol

Ethylhexylglycerin

Citric Acid

Caprylyl Glycol

Water, Glycerin, Propanediol, Squalane, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Copper Tripeptide-1, Acmella Oleracea Extract, Ectoin, Tetrapeptide-30, Palmitoyl Hexapeptide-52, Copper PCA, Panthenol, Sodium Polyglutamate, Camellia Sinensis Leaf Extract, Aloe Barbadensis Flower Extract, Passiflora Incarnata Flower Extract, Melia Azadirachta Leaf Extract, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Caprylyl Glycol

Caprylic/Capric Triglyceride

Helianthus Annuus Seed Oil

Bakuchiol

Krameria Triandra Root Extract

Plukenetia Volubilis Seed Oil

Moringa Oleifera Seed Oil

Tocopherol

Centella Asiatica Leaf Extract

Simmondsia Chinensis Seed Oil

Eclipta Prostrata Extract

Undecylenoyl Phenylalanine

Olea Europaea Fruit Oil

Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Bakuchiol, Krameria Triandra Root Extract, Plukenetia Volubilis Seed Oil, Moringa Oleifera Seed Oil, Tocopherol, Centella Asiatica Leaf Extract, Aloe Barbadensis Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Simmondsia Chinensis Seed Oil, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Ocimum Sanctum Leaf Extract, Eclipta Prostrata Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Undecylenoyl Phenylalanine, Olea Europaea Fruit Oil

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Aloe Barbadensis Flower Extract is the extract from the flowers of the aloe vera plant. In cosmetics, it functions as a skin conditioning agent.

Here's the honest part: most of the famous "aloe" research is on the leaf and this flower extract is much less studied. It shouldn't be assumed to do everything the gel is known for.

However, there is a small body of flower-specific research that is interesting to take a look at.

The flowers of Aloe vera contain volatile compounds and ascorbic acid. And when researchers looked closer, they found the flower is rich in antioxidants called phenolics that lined up with the extract's strong antioxidant activity.

This extract also showed some ability to fight off a common bacteria (Pseudomonas aeruginosa) in lab tests.

In lab and mouse studies, those phenolic compounds behaved like solid antioxidants though human skin trials on the flower extract are still needed.

Safety-wise, this ingredient is pretty assuring. The CIR Expert Panel deems this ingredient safe in current practices of use and only rare cases of acute eczema, contact urticaria, and dermatitis have been reported.

Coccinia Indica Fruit Extract is also known as Ivy Gourd Fruit Extract. It has skin conditioning properties.

The fruit is rich in flavonoids, phenolic acids, terpenoids, and sterols that show antioxidant and anti-inflammatory effect in vitro. This is because the fruit contains a thick mucilage that forms a protective and soothing layer on the skin's surface.

The extract itself has demonstrated antioxidant, soothing, and potential anti-allergy properties.

Most of this research is done in vitro and dedicated clinical studies on topical application are still limited.

Corallina Officinalis Extract is from the red seaweed, Corallina Officinalis. This seaweed is found all over the world but is most common in the rocky shores of Great Britain and Ireland.

Corallina Officinalis Extract contains antioxidant and emollient properties.

Extracted polysaccharides, galactose and xylose, in red algae showed antioxidant activity. Antioxidants help with anti-aging by neutralizing free-radical molecules. Free-radical molecules may damage your skin cells and DNA. Galactose is also a PHA.

Corallina Officinalis is structurally similar to coral due to its high calcium content.

Curcuma Longa Root Extract comes from the rhizome (underground stem) of the turmeric plant.

While the official EU Cosing Database lists this ingredient as a fragrance, it actually does more than give products a scent.

This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.

Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.

One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.

At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.

Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.

Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.

Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

The flowers of this tree are lilac colored.

This ingredient is also known as neem leaf extract. It contains natural compounds like nimbidin, quercetin, and other polyphenols that give it antibacterial, antifungal, and anti-inflammatory activity.

Lab studies have shown neem leaf extract can inhibit acne-related bacteria and help calm skin. Animal studies on wound gels using 1-3% neem leaf extract found it sped up healing without causing irritation.

A wound-healing study testing gels with the extract at 1%, 2%, and 3% concentrations and found none of them irritated the skin.

Most commercial products also use it in a similar low range (typically under 5%).

Allergy-wise, there are some case reports on neem oil causing allergic contact dermatitis so people with plant/botanical sensitivities may want to patch test first.

We don't have a description for Ocimum Basilicum Flower/Leaf Extract yet.

Ocimum Sanctum Leaf Extract comes from the Holy Basil plant. Holy Basil is native to India.

Holy Basil is rich in antioxidants due to its high romarinic acid, ferulic acid, and rutin content. This gives it skin brightening and soothing properties.

While Holy Basil has many claims to help fight acne, more research is needed.

One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.

This ingredient comes from eggplant (or aubergine). It has skin conditioning properties due to its abundance of antioxidants like Chlorogenic Acid, Caffeic Acid, and Nasunin.

Nasunin is the pigment concentrated in the purple peel and has demonstrated the abilityu to neutralize free radicals and bind excess iron in lab studies.

Lab studies have shown that eggplant extracts can lower oxidative stress and protect skin cell membranes from damage. A 2025 study found that specific compounds in eggplant (particularly a phenolamide called N-Trans-Feruloylputrescine) may support skin health by neutralizing 2-nonenal, a byproduct linked to aging skin.

Overall, this is a gentle, well-tolerated ingredient that adds a little extra antioxidant support to your routine.

Those with nighshade vegetable allergies (tomatoes, peppers, potatoes) should patch test as eggplant is part of the same family.

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