Biossance Squalane + Copper Peptide Rapid Plumping Serum Versus Naturium Multi-Peptide Advanced Serum

Biossance Squalane + Copper Peptide Rapid Plumping Serum Versus Naturium Multi-Peptide Advanced Serum

This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.

This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Propanediol

Squalane

Sodium Hyaluronate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Copper Tripeptide-1

Acmella Oleracea Extract

Ectoin

Tetrapeptide-30

Palmitoyl Hexapeptide-52

Copper PCA

Panthenol

Sodium Polyglutamate

Camellia Sinensis Leaf Extract

Aloe Barbadensis Flower Extract

Passiflora Incarnata Flower Extract

Melia Azadirachta Leaf Extract

Solanum Melongena Fruit Extract

Curcuma Longa Root Extract

Ocimum Basilicum Flower/Leaf Extract

Coccinia Indica Fruit Extract

Melia Azadirachta Flower Extract

Ocimum Sanctum Leaf Extract

Corallina Officinalis Extract

Polyacrylate Crosspolymer-6

Acacia Senegal Gum

Xanthan Gum

Phenoxyethanol

Ethylhexylglycerin

Citric Acid

Caprylyl Glycol

Water, Glycerin, Propanediol, Squalane, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Copper Tripeptide-1, Acmella Oleracea Extract, Ectoin, Tetrapeptide-30, Palmitoyl Hexapeptide-52, Copper PCA, Panthenol, Sodium Polyglutamate, Camellia Sinensis Leaf Extract, Aloe Barbadensis Flower Extract, Passiflora Incarnata Flower Extract, Melia Azadirachta Leaf Extract, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Caprylyl Glycol

Caprylic/Capric Triglyceride

Isopentyldiol

Ethylhexyl Polyhydroxystearate

Tetradecane

Glyceryl Stearate Citrate

Butyrospermum Parkii Butter

Polyglyceryl-3 Stearate

Helianthus Annuus Extract

Oryza Sativa Bran Extract

Mannitol

Phosphatidylcholine

Ferulic Acid

Arginine

Acetyl Hexapeptide-8

Copper Palmitoyl Heptapeptide-14

Palmitoyl Sh-Heptapeptide-12 Sp

Hydrolyzed Collagen

Rosmarinus Officinalis Leaf Extract

Lactic Acid/Glycolic Acid Copolymer

Tocopherol

Pullulan

Lysolecithin

Sclerotium Gum

Dimethicone

Sodium Phytate

Diglycerin

Hydrogenated Lecithin

Silica

Cetyl Alcohol

Hydroxyacetophenone

Polysorbate 60

Sorbitan Isostearate

Sodium Hydroxide

Sodium Benzoate

Potassium Sorbate

Polyvinyl Alcohol

Decyl Glucoside

Tocopheryl Acetate

Sodium Chloride

Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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