Skin science article
Biossance Squalane + Peptide Eye Gel Versus Drunk Elephant C-Firma Fresh Day Serum
Biossance Squalane + Peptide Eye Gel Versus Drunk Elephant C-Firma Fresh Day Serum This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin. This brightening serum is formulated around Ascorb
Biossance Squalane + Peptide Eye Gel Versus Drunk Elephant C-Firma Fresh Day Serum
This anti-aging eye moisturizer is formulated around Squalane and Niacinamide to soften the look of wrinkles and hydrate skin.
This brightening serum is formulated around Ascorbic Acid and Tocopherol to brighten dull-looking skin and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Aloe Barbadensis Leaf Juice
Squalane
Niacinamide
Glycerin
Panthenol
Chondrus Crispus Extract
Malus Domestica Fruit Cell Culture Extract
Acetyl Tetrapeptide-5
Acetyl Hexapeptide-8
Tocopherol
Pentylene Glycol
Cucumis Sativus Fruit Extract
Tetrahexyldecyl Ascorbate
Camellia Sinensis Leaf Extract
Lycium Barbarum Fruit Extract
Lycopene
Vitis Vinifera Skin Extract
Sodium Hyaluronate
Caffeine
Acacia Senegal Gum
Dimethicone Crosspolymer
Xanthan Gum
Carbomer
Ethyl Lauroyl Arginate Hcl
Lecithin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Silica
Phenoxyethanol
Potassium Sorbate
Citric Acid
Caprylyl Glycol
Water, Aloe Barbadensis Leaf Juice, Squalane, Niacinamide, Glycerin, Panthenol, Chondrus Crispus Extract, Malus Domestica Fruit Cell Culture Extract, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-8, Tocopherol, Pentylene Glycol, Cucumis Sativus Fruit Extract, Tetrahexyldecyl Ascorbate, Camellia Sinensis Leaf Extract, Lycium Barbarum Fruit Extract, Lycopene, Vitis Vinifera Skin Extract, Sodium Hyaluronate, Caffeine, Acacia Senegal Gum, Dimethicone Crosspolymer, Xanthan Gum, Carbomer, Ethyl Lauroyl Arginate Hcl, Lecithin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Phenoxyethanol, Potassium Sorbate, Citric Acid, Caprylyl Glycol
Dimethyl Isosorbide
Ascorbic Acid
Laureth-23
Lactobacillus/Pumpkin Ferment Extract
Sclerocarya Birrea Seed Oil
Dipotassium Glycyrrhizate
Glycyrrhiza Glabra Root Extract
Vitis Vinifera Juice Extract
Ferulic Acid
Phyllanthus Emblica Fruit Extract
Lactobacillus/Punica Granatum Fruit Ferment Extract
Propanediol
Gluconolactone
Sodium Hyaluronate Crosspolymer
Oryza Sativa Bran Extract
Glutamylamidoethyl Imidazole
Tetrahydrobisdemethoxydiferuloylmethane
Tetrahydrodemethoxydiferuloylmethane
Tetrahydrodiferuloylmethane
Caprylhydroxamic Acid
Leuconostoc/Radish Root Ferment Filtrate
Sorbic Acid
Sodium Benzoate
Ethylhexylglycerin
Water, Dimethyl Isosorbide, Ascorbic Acid, Laureth-23, Glycerin, Tocopherol, Lactobacillus/Pumpkin Ferment Extract, Sclerocarya Birrea Seed Oil, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Vitis Vinifera Juice Extract, Ferulic Acid, Phyllanthus Emblica Fruit Extract, Camellia Sinensis Leaf Extract, Lactobacillus/Punica Granatum Fruit Ferment Extract, Propanediol, Gluconolactone, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Oryza Sativa Bran Extract, Glutamylamidoethyl Imidazole, Tetrahydrobisdemethoxydiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrodiferuloylmethane, Pentylene Glycol, Caprylhydroxamic Acid, Leuconostoc/Radish Root Ferment Filtrate, Sorbic Acid, Phenoxyethanol, Sodium Benzoate, Caprylyl Glycol, Chondrus Crispus Extract, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Chondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.
The antioxidants in chondrus crispus include lutein and zeaxanthin. Lutein has the ability to filter blue light from screens.
Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.
What's the difference between algae and seaweed? Algae is a broad term that includes seaweed. Not all algae is seaweed.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!