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Biossance Squalane + Phyto-Retinol Serum Versus Medik8 Bakuchiol Peptides

Biossance Squalane + Phyto-Retinol Serum Versus Medik8 Bakuchiol Peptides This anti-aging serum is formulated around Squalane and Niacinamide to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is formulated around Bakuchiol a

By Peptide Skincare & Beauty Editorial TeamPublished

Biossance Squalane + Phyto-Retinol Serum Versus Medik8 Bakuchiol Peptides

This anti-aging serum is formulated around Squalane and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Bakuchiol and Centella Asiatica Leaf Extract to soften the look of wrinkles and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Squalane

Niacinamide

Sodium Acrylates Copolymer

Bakuchiol

Sodium Hyaluronate

Rosa Canina Fruit Oil

Citrus Aurantium Amara Peel Oil

Biosaccharide Gum-1

Yeast Extract

Soy Amino Acids

Lecithin

Hexylene Glycol

Ethylhexylglycerin

Caprylyl Glycol

Phenoxyethanol

Tetrasodium Glutamate Diacetate

Citric Acid

Linalool

Geraniol

Limonene

Water, Squalane, Niacinamide, Sodium Acrylates Copolymer, Bakuchiol, Sodium Hyaluronate, Rosa Canina Fruit Oil, Citrus Aurantium Amara Peel Oil, Biosaccharide Gum-1, Yeast Extract, Soy Amino Acids, Lecithin, Hexylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Tetrasodium Glutamate Diacetate, Citric Acid, Linalool, Geraniol, Limonene

Caprylic/Capric Triglyceride

Helianthus Annuus Seed Oil

Krameria Triandra Root Extract

Plukenetia Volubilis Seed Oil

Moringa Oleifera Seed Oil

Tocopherol

Centella Asiatica Leaf Extract

Aloe Barbadensis Flower Extract

Corallina Officinalis Extract

Coccinia Indica Fruit Extract

Solanum Melongena Fruit Extract

Simmondsia Chinensis Seed Oil

Curcuma Longa Root Extract

Ocimum Basilicum Flower/Leaf Extract

Ocimum Sanctum Leaf Extract

Eclipta Prostrata Extract

Melia Azadirachta Leaf Extract

Melia Azadirachta Flower Extract

Undecylenoyl Phenylalanine

Olea Europaea Fruit Oil

Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Bakuchiol, Krameria Triandra Root Extract, Plukenetia Volubilis Seed Oil, Moringa Oleifera Seed Oil, Tocopherol, Centella Asiatica Leaf Extract, Aloe Barbadensis Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Simmondsia Chinensis Seed Oil, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Ocimum Sanctum Leaf Extract, Eclipta Prostrata Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Undecylenoyl Phenylalanine, Olea Europaea Fruit Oil

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties.

You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to:

1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do

Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).

The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.

Systematic reviews also back this up:

Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.

The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.

This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

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Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties.
  4. 04You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to:
  5. 051) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do
  6. 06Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).
  7. 07The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.
  8. 08Systematic reviews also back this up:
  9. 09Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.
  10. 10The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.
  11. 11This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.
  12. 12Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
  13. 13Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
  14. 14In practice, that translates to a long shelf life and a consistently elegant skin feel.
  15. 15While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
  16. 16Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
  17. 17This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
  18. 18This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures…
  19. 19Tocopherol is a fat-soluble antioxidant known as Vitamin E.
  20. 20You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damag…
Source · skinsort.com ⟶
02

Product index

Related product references

Product

Medik8 Bakuchiol Peptides

Medik8 Bakuchiol Peptides Ingredients in Medik8 Bakuchiol Peptides explained: benefits, concerns, and detailed analysis of 21 ingredients including Caprylic/Capric Triglyceride, Helianthus …

Source: skinsort.comView reference →

Product

Medik8 Bakuchiol Peptides

Medik8 Bakuchiol Peptides Medik8 Bakuchiol Peptides ingredients explained: Caprylic/Capric Triglyceride, Helianthus Annuus (Sunflower) Seed Oil, Bakuchiol, Krameria Triandra Root Extract, P…

Source: incidecoder.comView reference →
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Comparison edit

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