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Boots Azelaic Acid Gel Cream Versus The INKEY List SuperSolutions 10% Azelaic Serum Redness Relief Solution

Boots Azelaic Acid Gel Cream Versus The INKEY List SuperSolutions 10% Azelaic Serum Redness Relief Solution This calming moisturizer is formulated around Azelaic Acid and Bisabolol to calm redness and clear breakouts. This calming serum is formulated around Az

Boots Azelaic Acid Gel Cream Versus The INKEY List SuperSolutions 10% Azelaic Serum Redness Relief Solution

This calming moisturizer is formulated around Azelaic Acid and Bisabolol to calm redness and clear breakouts.

This calming serum is formulated around Azelaic Acid to calm redness and clear breakouts.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Azelaic Acid

Caprylic/Capric Triglyceride

Behenyl Alcohol

Dimethicone

Glyceryl Stearate

Sorbitan Stearate

Polysorbate 60

Polyacrylate Crosspolymer-6

Phenoxyethanol

Potassium Hydroxide

Potassium Cetyl Phosphate

Bisabolol

Ethylhexylglycerin

Tocopheryl Acetate

Glycerin

O-Cymen-5-Ol

Disodium EDTA

Beta-Glucan

1,2-Hexanediol

Hydroxyacetophenone

Water, Butylene Glycol, Azelaic Acid, Caprylic/Capric Triglyceride, Behenyl Alcohol, Dimethicone, Glyceryl Stearate, Sorbitan Stearate, Polysorbate 60, Polyacrylate Crosspolymer-6, Phenoxyethanol, Potassium Hydroxide, Potassium Cetyl Phosphate, Bisabolol, Ethylhexylglycerin, Tocopheryl Acetate, Glycerin, O-Cymen-5-Ol, Disodium EDTA, Beta-Glucan, 1,2-Hexanediol, Hydroxyacetophenone

Propanediol

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Acacia Senegal Gum

Xanthan Gum

Allantoin

Sorbitan Isostearate

Maltodextrin

Sodium Hydroxide

Hydrolyzed Gardenia Florida Extract

Gardenia Florida Fruit Extract

Polylysine

Water, Azelaic Acid, Propanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Acacia Senegal Gum, Xanthan Gum, Allantoin, Glycerin, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Maltodextrin, Sodium Hydroxide, Hydrolyzed Gardenia Florida Extract, Gardenia Florida Fruit Extract, Polylysine

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes it special?

OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.

Here's what each tier does best:

Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.

Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.

In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.

Polysorbates are commonly used in medicine and foods.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Benzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.
  4. 04This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.
  5. 05As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.
  6. 06The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.
  7. 07This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.
  8. 08It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.
  9. 09Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.
  10. 10At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.
  11. 11Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  12. 12Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  13. 13Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  14. 14Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
  15. 15Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
  16. 16It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
  17. 17Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
  18. 18A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
  19. 19Dehydroacetic Acid is a synthetic preservative that keeps your products safe from microbes.
  20. 20As an organic acid, it penetrates microbial cell walls and disrupts cellular metabolism. This makes it effective against bacteria, yeast, and mold.
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Multi-Biotic

The Inkey List Multi-Biotic The Inkey List Multi-Biotic ingredients explained: Water (Aqua/Eau), Inulin, Glycerin, Isoamyl Laurate, Propanediol, Squalane, Cetearyl Olivate, Sorbitan Olivate…

Source: incidecoder.comView reference →
03

Comparison edit

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