Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Boots Dermacare Ceramides Moisturising Cream Versus The INKEY List Bio-Active Ceramide Repairing and Plumping Moisturizer

Boots Dermacare Ceramides Moisturising Cream Versus The INKEY List Bio-Active Ceramide Repairing and Plumping Moisturizer This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrat

Boots Dermacare Ceramides Moisturising Cream Versus The INKEY List Bio-Active Ceramide Repairing and Plumping Moisturizer

This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Ethylhexyl Palmitate

Glycerin

Cetearyl Alcohol

Dimethicone

Butyrospermum Parkii Butter

PEG-100 Stearate

Glyceryl Stearate

Phenoxyethanol

Carbomer

Tocopheryl Acetate

Allantoin

Squalane

Sodium Hyaluronate

Ethylhexylglycerin

Cetearyl Glucoside

Caprylyl Glycol

Sodium Hydroxide

Disodium EDTA

Octyldodecanol

Hydrogenated Lecithin

Ceramide NP

Polyglyceryl-10 Stearate

1,2-Hexanediol

Sucrose Stearate

Phytosphingosine

Cholesterol

Phospholipids

Ceramide Ns

Ceramide Ng

Ceramide As

Ceramide AP

Ceramide EOP

Water, Ethylhexyl Palmitate, Glycerin, Cetearyl Alcohol, Dimethicone, Butyrospermum Parkii Butter, PEG-100 Stearate, Glyceryl Stearate, Phenoxyethanol, Carbomer, Tocopheryl Acetate, Allantoin, Squalane, Sodium Hyaluronate, Ethylhexylglycerin, Cetearyl Glucoside, Caprylyl Glycol, Sodium Hydroxide, Disodium EDTA, Octyldodecanol, Hydrogenated Lecithin, Ceramide NP, Polyglyceryl-10 Stearate, 1,2-Hexanediol, Sucrose Stearate, Phytosphingosine, Cholesterol, Phospholipids, Ceramide Ns, Ceramide Ng, Ceramide As, Ceramide AP, Ceramide EOP

C12-15 Alkyl Benzoate

Propanediol

Polysilicone-11

C10-18 Triglycerides

Caprylic/Capric Triglyceride

Pentaerythrityl Tetraisostearate

Cetearyl Olivate

Sorbitan Olivate

Cetyl Alcohol

Polyacrylate-13

Hydrogenated Polyisobutene

Polyglyceryl-10 Laurate

Laureth-12

Sorbitan Isostearate

Hdi/Trimethylol Hexyllactone Crosspolymer

Polymethylsilsesquioxane

Citric Acid

Water, Glycerin, Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Propanediol, Polysilicone-11, C10-18 Triglycerides, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraisostearate, Cetearyl Olivate, Sorbitan Olivate, Cetyl Alcohol, Phenoxyethanol, Ceramide NP, Polyacrylate-13, Hydrogenated Polyisobutene, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Ethylhexyl Palmitate, Laureth-12, Sorbitan Isostearate, Hdi/Trimethylol Hexyllactone Crosspolymer, Polymethylsilsesquioxane, Citric Acid, Sodium Hydroxide

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.

In cosmetics, it plays many roles:

One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.

For most people, this is a well-tolerated and lightweight ingredient.

This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Inulin
  3. 03Glycerin
  4. 04Isoamyl Laurate
  5. 05Propanediol
  6. 06Squalane
  7. 07Cetearyl Olivate
  8. 08Sorbitan Olivate
  9. 09Avena Sativa Kernel Oil
  10. 10Phenoxyethanol
  11. 11Yogurt Powder
  12. 12Sodium Caproyl Prolinate
  13. 13Carbomer
  14. 14Isoamyl Cocoate
  15. 15Benzyl Alcohol
  16. 16Sodium Hyaluronate
  17. 17Sodium Stearoyl Glutamate
  18. 18Ethylhexylglycerin
  19. 19Diglucosyl Gallic Acid
  20. 20Trisodium Ethylenediamine Disuccinate
Source · skinsort.com
02

Product index

Related product references

Product

The Inkey List Brighten-I Eye Cream

The Inkey List Brighten-I Eye Cream The Inkey List Brighten-I Eye Cream ingredients explained: Water (Aqua/Eau), Cyclopentasiloxane, Coco-Caprylate/Caprate, Glycerin, Caprylic/Capric Trigly…

Source: incidecoder.comView reference →
03

Comparison edit

Read side by side