Boots Dermacare Eczema Treatment Cream Versus The INKEY List Ectoin Hydro-Barrier Serum

Boots Dermacare Eczema Treatment Cream Versus The INKEY List Ectoin Hydro-Barrier Serum

This barrier-repair serum is formulated around Ectoin and Panthenol to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Ectoin

Water

Hydrogenated Lecithin

Ceramide NP

Squalane

Olea Europaea Fruit Oil

Caprylic/Capric Triglyceride

Butyrospermum Parkii Butter

Oryza Sativa Bran Cera

Carbomer

Xanthan Gum

Sodium Carbomer

Cardiospermum Halicacabum Flower/Leaf/Vine Extract

Glycine

Alanine

Pentylene Glycol

Butylene Glycol

Hydroxyethylcellulose

Glycerin

Hydroxyphenyl Propamidobenzoic Acid

Ectoin, Water, Hydrogenated Lecithin, Ceramide NP, Squalane, Olea Europaea Fruit Oil, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, Oryza Sativa Bran Cera, Carbomer, Xanthan Gum, Sodium Carbomer, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Glycine, Alanine, Pentylene Glycol, Butylene Glycol, Hydroxyethylcellulose, Glycerin, Hydroxyphenyl Propamidobenzoic Acid

Propanediol

Coconut Alkanes

Ectoin 2%

Hydrolyzed Sodium Hyaluronate

Sodium Hyaluronate

Maltodextrin

Phenoxyethanol

Sodium Stearoyl Glutamate

Panthenol

Cetearyl Alcohol

Sclerotium Gum

Glyceryl Stearate

Jojoba Esters

Coco-Caprylate/Caprate

Ethylhexylglycerin

Sodium Citrate

Helianthus Annuus Seed Wax

Citric Acid

Polyglyceryl-10 Stearate

Avena Sativa Kernel Extract

Leuconostoc/Radish Root Ferment Filtrate

Triethyl Citrate

Polyglyceryl-6 Behenate

Sodium Hyaluronate Crosspolymer

Hyaluronic Acid

Ceramide AP

Cholesterol

Phytosphingosine

Behenic Acid

Sodium Levulinate

Polyglycerin-3

Potassium Sorbate

Sodium Cetearyl Sulfate

Ceramide EOP

Water, Propanediol, Caprylic/Capric Triglyceride, Coconut Alkanes, Ectoin 2%, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Maltodextrin, Phenoxyethanol, Sodium Stearoyl Glutamate, Panthenol, Cetearyl Alcohol, Sclerotium Gum, Xanthan Gum, Glyceryl Stearate, Jojoba Esters, Coco-Caprylate/Caprate, Ethylhexylglycerin, Sodium Citrate, Helianthus Annuus Seed Wax, Citric Acid, Polyglyceryl-10 Stearate, Avena Sativa Kernel Extract, Glycerin, Leuconostoc/Radish Root Ferment Filtrate, Triethyl Citrate, Pentylene Glycol, Polyglyceryl-6 Behenate, Sodium Hyaluronate Crosspolymer, Ceramide NP, Hyaluronic Acid, Ceramide AP, Cholesterol, Phytosphingosine, Behenic Acid, Sodium Levulinate, Polyglycerin-3, Potassium Sorbate, Sodium Cetearyl Sulfate, Ceramide EOP

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ectoin is a compound found naturally in some species of bacteria. It can be synthetically created for skincare use.

This ingredient is an osmolyte; Osmolytes help organisms survive osmotic shock (it protects them from extreme conditions). It does this by influencing the properties of biological fluids within cells.

When applied to the skin, ectoin helps bind water molecules to protect our skin. The water forms a sort of armor for the parts of our skin cells, enzymes, proteins, and more.

Besides this, ectoin has many uses in skincare:

A study from 2004 found ectoin to counteract the damage from UV-A exposure at different cell levels. It has also been shown to protect skin against both UV-A, UV-B rays, infrared light, and visible light.

Studies show ectoin to have dual-action pollution protection: first, it protects our skin from further pollution damage. Second, it helps repair damage from pollution.

In fact, ectoin has been shown to help with:

Fun fact: In the EU, ectoin is used in inhalation medication as an anti-pollution ingredient.

Ectoin is a highly stable ingredient. It has a wide pH range of 1-9. Light, oxygen, and temperature do not affect this ingredient.

The chemical name for this ingredient is Tetrahydromethylpyrimidine Carboxylic Acid.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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