Boots Hyaluronic Acid Moisturizer Versus The INKEY List Multi-Biotic Moisturizer

Boots Hyaluronic Acid Moisturizer Versus The INKEY List Multi-Biotic Moisturizer

This barrier-repair moisturizer is formulated around Squalane and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Inulin and Squalane to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Ethylhexyl Palmitate

Dimethicone

Butylene Glycol

Squalane

C14-22 Alcohols

Sodium Hyaluronate

Phenoxyethanol

Carbomer

PEG-100 Stearate

Methylparaben

Glyceryl Stearate

C12-20 Alkyl Glucoside

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Ethylhexylglycerin

Sodium Hydroxide

Isohexadecane

Disodium EDTA

Polysorbate 80

Sorbitan Oleate

Water, Glycerin, Ethylhexyl Palmitate, Dimethicone, Butylene Glycol, Squalane, C14-22 Alcohols, Sodium Hyaluronate, Phenoxyethanol, Carbomer, PEG-100 Stearate, Methylparaben, Glyceryl Stearate, C12-20 Alkyl Glucoside, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Ethylhexylglycerin, Sodium Hydroxide, Isohexadecane, Disodium EDTA, Polysorbate 80, Sorbitan Oleate

Inulin

Isoamyl Laurate

Propanediol

Cetearyl Olivate

Sorbitan Olivate

Avena Sativa Kernel Oil

Yogurt Powder

Sodium Caproyl Prolinate

Isoamyl Cocoate

Benzyl Alcohol

Sodium Stearoyl Glutamate

Diglucosyl Gallic Acid

Trisodium Ethylenediamine Disuccinate

Dehydroacetic Acid

Polysorbate 60

Citric Acid

Heptapeptide-7

Lecithin

Potassium Sorbate

Sodium Benzoate

Xanthan Gum

Sorbitan Isostearate

Water, Inulin, Glycerin, Isoamyl Laurate, Propanediol, Squalane, Cetearyl Olivate, Sorbitan Olivate, Avena Sativa Kernel Oil, Phenoxyethanol, Yogurt Powder, Sodium Caproyl Prolinate, Carbomer, Isoamyl Cocoate, Benzyl Alcohol, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Ethylhexylglycerin, Diglucosyl Gallic Acid, Trisodium Ethylenediamine Disuccinate, Dehydroacetic Acid, Polysorbate 60, Citric Acid, Heptapeptide-7, Lecithin, Potassium Sorbate, Sodium Benzoate, Xanthan Gum, Sorbitan Isostearate

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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