Skin science article
Boots Peptide Serum Versus Naturium Multi-Peptide Advanced Serum
Boots Peptide Serum Versus Naturium Multi-Peptide Advanced Serum This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-1 to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is formulated around Acetyl
Boots Peptide Serum Versus Naturium Multi-Peptide Advanced Serum
This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-1 to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Butylene Glycol
Niacinamide
Pentylene Glycol
1,2-Hexanediol
Betaine
Trehalose
Ammonium Polyacryloyldimethyl Taurate
Xanthan Gum
Sodium PCA
Allantoin
Hydroxyacetophenone
Carnosine
Sodium Lactate
PCA
Polyacrylate Crosspolymer-6
Sodium Hyaluronate
Disodium EDTA
Serine
Alanine
Glycine
Sodium Hyaluronate Crosspolymer
Glutamic Acid
Lysine Hcl
Carbomer
Threonine
Arginine
Polysorbate 20
Proline
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Water, Glycerin, Butylene Glycol, Niacinamide, Pentylene Glycol, 1,2-Hexanediol, Betaine, Trehalose, Ammonium Polyacryloyldimethyl Taurate, Xanthan Gum, Sodium PCA, Allantoin, Hydroxyacetophenone, Carnosine, Sodium Lactate, PCA, Polyacrylate Crosspolymer-6, Sodium Hyaluronate, Disodium EDTA, Serine, Alanine, Glycine, Sodium Hyaluronate Crosspolymer, Glutamic Acid, Lysine Hcl, Carbomer, Threonine, Arginine, Polysorbate 20, Proline, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
Propanediol
Caprylic/Capric Triglyceride
Isopentyldiol
Ethylhexyl Polyhydroxystearate
Squalane
Tetradecane
Glyceryl Stearate Citrate
Butyrospermum Parkii Butter
Polyglyceryl-3 Stearate
Helianthus Annuus Extract
Oryza Sativa Bran Extract
Mannitol
Phosphatidylcholine
Ferulic Acid
Acetyl Hexapeptide-8
Copper Palmitoyl Heptapeptide-14
Palmitoyl Sh-Heptapeptide-12 Sp
Hydrolyzed Collagen
Rosmarinus Officinalis Leaf Extract
Lactic Acid/Glycolic Acid Copolymer
Tocopherol
Pullulan
Lysolecithin
Sclerotium Gum
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Dimethicone
Sodium Phytate
Diglycerin
Hydrogenated Lecithin
Silica
Cetyl Alcohol
Polysorbate 60
Sorbitan Isostearate
Sodium Hydroxide
Sodium Benzoate
Potassium Sorbate
Polyvinyl Alcohol
Decyl Glucoside
Tocopheryl Acetate
Sodium Chloride
Citric Acid
Phenoxyethanol
Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.