Skin science article
Bueno MGF Peptide Serum Plus Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum
Bueno MGF Peptide Serum Plus Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum This anti-aging serum is formulated around Allantoin and Adenosine to soften the look of wrinkles and fade the look of dark spots. This anti-aging serum is formulated
Bueno MGF Peptide Serum Plus Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum
This anti-aging serum is formulated around Allantoin and Adenosine to soften the look of wrinkles and fade the look of dark spots.
This anti-aging serum is formulated around Sh-Oligopeptide-1 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Glycerin
1,2-Hexanediol
Eclipta Prostrata Extract
Trehalose
Biosaccharide Gum-1
Methyl Methacrylate Crosspolymer
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Arginine
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Isohexadecane
Allantoin
Xanthan Gum
Adenosine
Polysorbate 80
Sodium Chondroitin Sulfate
Polysorbate 20
Disodium EDTA
Lavandula Angustifolia Oil
Lecithin
Sorbitan Oleate
Sh-Oligopeptide-1
Sh-Polypeptide-1
Sh-Polypeptide-16
Sh-Polypeptide-4
Nicotinoyl Hexapeptide-44
Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Eclipta Prostrata Extract, Trehalose, Biosaccharide Gum-1, Methyl Methacrylate Crosspolymer, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Arginine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Isohexadecane, Allantoin, Xanthan Gum, Adenosine, Polysorbate 80, Sodium Chondroitin Sulfate, Polysorbate 20, Disodium EDTA, Lavandula Angustifolia Oil, Lecithin, Sorbitan Oleate, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Polypeptide-16, Sh-Polypeptide-4, Nicotinoyl Hexapeptide-44
Heptyl Glucoside
Isodecyl Neopentanoate
Acacia Senegal Gum
Centella Asiatica Leaf Extract
Helianthus Annuus Seed Oil
Tocopherol
Phospholipids
Glycolipids
Dimethyl Sulfone
Ornithine
Hydrogenated Lecithin
Copper Lysinate/Prolinate
Methylglucoside Phosphate
Crocus Chrysanthus Bulb Extract
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Pentapeptide-18
Pentapeptide-48
Butyrospermum Parkii Butter
Leuconostoc/Radish Root Ferment Filtrate
Caprylic/Capric Triglyceride
Ethylhexylglycerin
C12-15 Alkyl Benzoate
Sclerotium Gum
Caprylyl Glycol
Levulinic Acid
P-Anisic Acid
Sodium Gluconate
Propanediol
Maltodextrin
Citric Acid
Sodium Hydroxide
Heptanol
Phenethyl Alcohol
Phenoxyethanol
Water, Glycerin, Heptyl Glucoside, Isodecyl Neopentanoate, Acacia Senegal Gum, Polysorbate 20, Centella Asiatica Leaf Extract, Helianthus Annuus Seed Oil, Tocopherol, Phospholipids, Glycolipids, Dimethyl Sulfone, Ornithine, Lecithin, Hydrogenated Lecithin, Copper Lysinate/Prolinate, Methylglucoside Phosphate, Crocus Chrysanthus Bulb Extract, Sh-Oligopeptide-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Pentapeptide-18, Pentapeptide-48, Butyrospermum Parkii Butter, Leuconostoc/Radish Root Ferment Filtrate, Caprylic/Capric Triglyceride, Ethylhexylglycerin, C12-15 Alkyl Benzoate, Sclerotium Gum, Xanthan Gum, Caprylyl Glycol, Levulinic Acid, P-Anisic Acid, Sodium Gluconate, Propanediol, Maltodextrin, Citric Acid, Sodium Hydroxide, Heptanol, Phenethyl Alcohol, Phenoxyethanol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.