Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Bueno MGF Peptide Serum Plus Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum

Bueno MGF Peptide Serum Plus Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum This anti-aging serum is formulated around Allantoin and Adenosine to soften the look of wrinkles and fade the look of dark spots. This anti-aging serum is formulated

Bueno MGF Peptide Serum Plus Versus Allies of Skin Multi Peptides & GF Advanced Lifting Serum

This anti-aging serum is formulated around Allantoin and Adenosine to soften the look of wrinkles and fade the look of dark spots.

This anti-aging serum is formulated around Sh-Oligopeptide-1 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

1,2-Hexanediol

Eclipta Prostrata Extract

Trehalose

Biosaccharide Gum-1

Methyl Methacrylate Crosspolymer

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Arginine

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Isohexadecane

Allantoin

Xanthan Gum

Adenosine

Polysorbate 80

Sodium Chondroitin Sulfate

Polysorbate 20

Disodium EDTA

Lavandula Angustifolia Oil

Lecithin

Sorbitan Oleate

Sh-Oligopeptide-1

Sh-Polypeptide-1

Sh-Polypeptide-16

Sh-Polypeptide-4

Nicotinoyl Hexapeptide-44

Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Eclipta Prostrata Extract, Trehalose, Biosaccharide Gum-1, Methyl Methacrylate Crosspolymer, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Arginine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Isohexadecane, Allantoin, Xanthan Gum, Adenosine, Polysorbate 80, Sodium Chondroitin Sulfate, Polysorbate 20, Disodium EDTA, Lavandula Angustifolia Oil, Lecithin, Sorbitan Oleate, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Polypeptide-16, Sh-Polypeptide-4, Nicotinoyl Hexapeptide-44

Heptyl Glucoside

Isodecyl Neopentanoate

Acacia Senegal Gum

Centella Asiatica Leaf Extract

Helianthus Annuus Seed Oil

Tocopherol

Phospholipids

Glycolipids

Dimethyl Sulfone

Ornithine

Hydrogenated Lecithin

Copper Lysinate/Prolinate

Methylglucoside Phosphate

Crocus Chrysanthus Bulb Extract

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Pentapeptide-18

Pentapeptide-48

Butyrospermum Parkii Butter

Leuconostoc/Radish Root Ferment Filtrate

Caprylic/Capric Triglyceride

Ethylhexylglycerin

C12-15 Alkyl Benzoate

Sclerotium Gum

Caprylyl Glycol

Levulinic Acid

P-Anisic Acid

Sodium Gluconate

Propanediol

Maltodextrin

Citric Acid

Sodium Hydroxide

Heptanol

Phenethyl Alcohol

Phenoxyethanol

Water, Glycerin, Heptyl Glucoside, Isodecyl Neopentanoate, Acacia Senegal Gum, Polysorbate 20, Centella Asiatica Leaf Extract, Helianthus Annuus Seed Oil, Tocopherol, Phospholipids, Glycolipids, Dimethyl Sulfone, Ornithine, Lecithin, Hydrogenated Lecithin, Copper Lysinate/Prolinate, Methylglucoside Phosphate, Crocus Chrysanthus Bulb Extract, Sh-Oligopeptide-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Pentapeptide-18, Pentapeptide-48, Butyrospermum Parkii Butter, Leuconostoc/Radish Root Ferment Filtrate, Caprylic/Capric Triglyceride, Ethylhexylglycerin, C12-15 Alkyl Benzoate, Sclerotium Gum, Xanthan Gum, Caprylyl Glycol, Levulinic Acid, P-Anisic Acid, Sodium Gluconate, Propanediol, Maltodextrin, Citric Acid, Sodium Hydroxide, Heptanol, Phenethyl Alcohol, Phenoxyethanol

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Glycerin
  3. 03Heptyl Glucoside
  4. 04Isodecyl Neopentanoate
  5. 05Acacia Senegal Gum
  6. 06Polysorbate 20
  7. 07Centella Asiatica Leaf Extract
  8. 08Helianthus Annuus Seed Oil
  9. 09Tocopherol
  10. 10Phospholipids
  11. 11Glycolipids
  12. 12Dimethyl Sulfone
  13. 13Ornithine
  14. 14Lecithin
  15. 15Hydrogenated Lecithin
  16. 16Copper Lysinate/Prolinate
  17. 17Methylglucoside Phosphate
  18. 18Crocus Chrysanthus Bulb Extract
  19. 19Sh-Oligopeptide-1
  20. 20Dipeptide Diaminobutyroyl Benzylamide Diacetate
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side

04

Ask the journal

Related questions

01What if I have acne-prone skin?

The formulations are generally non-comedogenic but individual responses vary. Peptides themselves do not cause acne and may help improve scarring and inflammation. Start with one product at a time to identify any that trigger breakouts for your specific skin.

Source · seekpeptides.com