Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Burt's Bees Vitamin C + E + F Serum with Lotus Extract Versus First Aid Beauty 10% Vitamin C Brightening Serum

Burt's Bees Vitamin C + E + F Serum with Lotus Extract Versus First Aid Beauty 10% Vitamin C Brightening Serum This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Tocopherol to brighten dull-looking skin and fade the look of dark spots. T

Burt's Bees Vitamin C + E + F Serum with Lotus Extract Versus First Aid Beauty 10% Vitamin C Brightening Serum

This brightening serum is formulated around Tetrahexyldecyl Ascorbate and Tocopherol to brighten dull-looking skin and fade the look of dark spots.

This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Colloidal Oatmeal to brighten dull-looking skin and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Carthamus Tinctorius Seed Oil

Silica

Coconut Alkanes

Glycerin

Squalane

Tetrahexyldecyl Ascorbate

Propanediol

Nelumbo Nucifera Extract

Chamomilla Recutita Flower Extract

Helianthus Annuus Seed Oil

Tocopherol

Lauryl Glucoside

Polyglyceryl-6 Laurate

Myristyl Glucoside

Xanthan Gum

Parfum

Coco-Caprylate/Caprate

Potassium Sorbate

Citric Acid

Lecithin

Sclerotium Gum

Linoleic Acid

Linolenic Acid

Pullulan

Sodium Phytate

Gellan Gum

Ascorbic Acid

Alcohol

Sodium PCA

Sodium Benzoate

Phenoxyethanol

Amyl Cinnamal

Benzyl Salicylate

Geraniol

Limonene

Water, Carthamus Tinctorius Seed Oil, Silica, Coconut Alkanes, Glycerin, Squalane, Tetrahexyldecyl Ascorbate, Propanediol, Nelumbo Nucifera Extract, Chamomilla Recutita Flower Extract, Helianthus Annuus Seed Oil, Tocopherol, Lauryl Glucoside, Polyglyceryl-6 Laurate, Myristyl Glucoside, Xanthan Gum, Parfum, Coco-Caprylate/Caprate, Potassium Sorbate, Citric Acid, Lecithin, Sclerotium Gum, Linoleic Acid, Linolenic Acid, Pullulan, Sodium Phytate, Gellan Gum, Ascorbic Acid, Alcohol, Sodium PCA, Sodium Benzoate, Phenoxyethanol, Amyl Cinnamal, Benzyl Salicylate, Geraniol, Limonene

3-O-Ethyl Ascorbic Acid

Sodium Citrate

Tocopheryl Acetate

Colloidal Oatmeal

Chrysanthemum Parthenium Extract

Camellia Sinensis Leaf Extract

Glycyrrhiza Glabra Root Extract

Polyglyceryl-6 Polyricinoleate

Polyglyceryl-10 Dioleate

Sodium Hydroxide

Tetrasodium EDTA

Water, 3-O-Ethyl Ascorbic Acid, Squalane, Sodium Citrate, Tocopheryl Acetate, Colloidal Oatmeal, Chrysanthemum Parthenium Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Glycerin, Polyglyceryl-6 Polyricinoleate, Xanthan Gum, Polyglyceryl-10 Dioleate, Phenoxyethanol, Citric Acid, Sodium Benzoate, Potassium Sorbate, Sodium Hydroxide, Tetrasodium EDTA

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Polylactic Acid
  3. 03Glycolic Acid
  4. 04Sodium Hydroxide
  5. 05Hexyl Laurate
  6. 06Cetyl Alcohol
  7. 07Stearyl Alcohol
  8. 08Sorbitol
  9. 09Lactic Acid
  10. 10Dimethicone
  11. 11Cetearyl Alcohol
  12. 12Glycerin
  13. 13Sodium Lauroyl Lactylate
  14. 14Phenoxyethanol
  15. 15Cetearyl Glucoside
  16. 16Parfum
  17. 17Caprylyl Glycol
  18. 18Dehydroxanthan Gum
  19. 19Ethylhexylglycerin
  20. 20Hexylene Glycol
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side