Skin science article
Caudalie Resveratrol Lift Instant Firming Serum Versus MediCube PDRN Pink Peptide Serum
Caudalie Resveratrol Lift Instant Firming Serum Versus MediCube PDRN Pink Peptide Serum This anti-aging serum is formulated around Palmitoyl Grapevine Shoot Extract and Hyaluronic Acid to soften the look of wrinkles and brighten dull-looking skin. This anti-ag
Caudalie Resveratrol Lift Instant Firming Serum Versus MediCube PDRN Pink Peptide Serum
This anti-aging serum is formulated around Palmitoyl Grapevine Shoot Extract and Hyaluronic Acid to soften the look of wrinkles and brighten dull-looking skin.
This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Butylene Glycol
Glycerin
Hexyldecanol
Hexyldecyl Laurate
Squalane
Tocopheryl Acetate
C20-22 Alkyl Phosphate
Palmitoyl Grapevine Shoot Extract
C20-22 Alcohols
Potassium Cetyl Phosphate
Polyacrylate Crosspolymer-6
Helianthus Annuus Seed Oil
Caprylyl Glycol
Parfum
Hydrolyzed Hyaluronic Acid
Sodium Dehydroacetate
Hyaluronic Acid
Adenosine
Sodium Hydroxide
Acetyl Dipeptide-1 Cetyl Ester
Pentylene Glycol
Sodium Phytate
Khaya Senegalensis Bark Extract
Maltodextrin
Linalool
Limonene
Paeonia Lactiflora Root Extract
Coumarin
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47
Water, Butylene Glycol, Glycerin, Hexyldecanol, Hexyldecyl Laurate, Squalane, Tocopheryl Acetate, C20-22 Alkyl Phosphate, Palmitoyl Grapevine Shoot Extract, C20-22 Alcohols, Potassium Cetyl Phosphate, Polyacrylate Crosspolymer-6, Helianthus Annuus Seed Oil, Caprylyl Glycol, Parfum, Hydrolyzed Hyaluronic Acid, Sodium Dehydroacetate, Hyaluronic Acid, Adenosine, Sodium Hydroxide, Acetyl Dipeptide-1 Cetyl Ester, Pentylene Glycol, Sodium Phytate, Khaya Senegalensis Bark Extract, Maltodextrin, Linalool, Limonene, Paeonia Lactiflora Root Extract, Coumarin, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-47
Dipropylene Glycol
Isopropyl Myristate
Glycereth-26
Niacinamide
1,2-Hexanediol
Sodium DNA
Polyglycerin-3
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Polyisobutene
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Milt Extract
Tromethamine
Glyceryl Acrylate/Acrylic Acid Copolymer
Pvm/Ma Copolymer
Ethylhexylglycerin
Melia Azadirachta Leaf Extract
Caprylyl/Capryl Glucoside
Sorbitan Oleate
Melia Azadirachta Flower Extract
Sodium Hyaluronate
Disodium EDTA
Curcuma Longa Root Extract
Cyanocobalamin
Hydrolyzed Collagen
Ubiquinone
Ocimum Sanctum Leaf Extract
Corallina Officinalis Extract
Palmitoyl Pentapeptide-4
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Copper Tripeptide-1
Acetyl Hexapeptide-8
Salmon Egg Extract
Atelocollagen
Water, Glycerin, Dipropylene Glycol, Isopropyl Myristate, Glycereth-26, Niacinamide, 1,2-Hexanediol, Sodium DNA, Butylene Glycol, Polyglycerin-3, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Milt Extract, Tromethamine, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Ethylhexylglycerin, Caprylyl Glycol, Parfum, Melia Azadirachta Leaf Extract, Adenosine, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Disodium EDTA, Curcuma Longa Root Extract, Cyanocobalamin, Hydrolyzed Collagen, Ubiquinone, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8, Salmon Egg Extract, Atelocollagen
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!