Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Celimax Dual Barrier Skin Wearable Cream Versus Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream

Celimax Dual Barrier Skin Wearable Cream Versus Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream This barrier-repair moisturizer is formulated around Panthenol and Ceramide NP to strengthen the skin barrier and hydrate skin. This anti-aging moistur

Celimax Dual Barrier Skin Wearable Cream Versus Haruharu Wonder Centella Phyto & 5 Peptide Concentrate Cream

This barrier-repair moisturizer is formulated around Panthenol and Ceramide NP to strengthen the skin barrier and hydrate skin.

This anti-aging moisturizer is formulated around Centella Asiatica Extract and Madecassoside to soften the look of wrinkles and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Caprylic/Capric Triglyceride

Butylene Glycol

Propanediol

Stearic Acid

Cetearyl Alcohol

Methyl Trimethicone

Caprylyl Methicone

1,2-Hexanediol

C12-16 Alcohols

Panthenol

Olea Europaea Fruit Oil

Hydrogenated Lecithin

Glyceryl Stearate

Palmitic Acid

Cetearyl Glucoside

Ceramide NP

Carbomer

Tromethamine

Allantoin

Xanthan Gum

Tocopherol

Ethylhexylglycerin

Dipropylene Glycol

Disodium EDTA

Pantolactone

Sodium Hyaluronate

Heptasodium Hexacarboxymethyl Dipeptide-12

Malt Extract

Ceramide Ns

Phytosphingosine

Cholesterol

Ceramide As

Ceramide AP

Ceramide EOP

Water, Glycerin, Caprylic/Capric Triglyceride, Butylene Glycol, Propanediol, Stearic Acid, Cetearyl Alcohol, Methyl Trimethicone, Caprylyl Methicone, 1,2-Hexanediol, C12-16 Alcohols, Panthenol, Olea Europaea Fruit Oil, Hydrogenated Lecithin, Glyceryl Stearate, Palmitic Acid, Cetearyl Glucoside, Ceramide NP, Carbomer, Tromethamine, Allantoin, Xanthan Gum, Tocopherol, Ethylhexylglycerin, Dipropylene Glycol, Disodium EDTA, Pantolactone, Sodium Hyaluronate, Heptasodium Hexacarboxymethyl Dipeptide-12, Malt Extract, Ceramide Ns, Phytosphingosine, Cholesterol, Ceramide As, Ceramide AP, Ceramide EOP

Helianthus Annuus Seed Oil

Polyglyceryl-3 Distearate

Cetyl Alcohol

Cetyl Palmitate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Sorbitan Palmitate

Sorbitan Olivate

Stearyl Alcohol

Glyceryl Stearate Citrate

Myristyl Alcohol

Squalane

Caffeine

Hydrolyzed Soy Protein

Pentylene Glycol

Adenosine

Butyrospermum Parkii Butter

Phytosterols

Lauryl Alcohol

Centella Asiatica Extract

Hydrolyzed Pea Protein

Madecassoside

Asiaticoside

Caprylyl Glycol

Xylitylglucoside

Anhydroxylitol

Copper Tripeptide-1

Xylitol

Acetyl Hexapeptide-8

Asiatic Acid

Madecassic Acid

Glucose

Hippophae Rhamnoides Fruit Extract

Oligopeptide-32

Oligopeptide-29

Palmitoyl Pentapeptide-4

Water, Glycerin, Butylene Glycol, Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Polyglyceryl-3 Distearate, 1,2-Hexanediol, Cetyl Alcohol, Cetyl Palmitate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sorbitan Palmitate, Sorbitan Olivate, Glyceryl Stearate, Stearyl Alcohol, Xanthan Gum, Glyceryl Stearate Citrate, Myristyl Alcohol, Squalane, Caffeine, Hydrolyzed Soy Protein, Hydrogenated Lecithin, Pentylene Glycol, Ethylhexylglycerin, Adenosine, Butyrospermum Parkii Butter, Phytosterols, Lauryl Alcohol, Centella Asiatica Extract, Hydrolyzed Pea Protein, Madecassoside, Asiaticoside, Caprylyl Glycol, Xylitylglucoside, Anhydroxylitol, Copper Tripeptide-1, Xylitol, Acetyl Hexapeptide-8, Asiatic Acid, Madecassic Acid, Glucose, Ceramide NP, Hippophae Rhamnoides Fruit Extract, Oligopeptide-32, Oligopeptide-29, Palmitoyl Pentapeptide-4

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 031,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
  4. 04It is a:
  5. 05Humectant, drawing moisture into the skin
  6. 06Emollient, helping to soften skin
  7. 07Solvent, dispersing and stabilizing formulas
  8. 08Preservative booster, enhancing the antimicrobial activity of other preservatives
  9. 09Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
  10. 10The way it works is fairly well mapped out:
  11. 11Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down o…
  12. 12The clinical backing is pretty solid too.
  13. 13A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at…
  14. 14A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
  15. 15On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
  16. 16This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
  17. 17Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
  18. 18Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  19. 19Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  20. 20Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

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