Skin science article
Celimax Noni Ampoule Calming + Radiance Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum
Celimax Noni Ampoule Calming + Radiance Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum This calming ampoule is formulated around Morinda Citrifolia Fruit Extract and Allantoin to calm redness and brighten dull-looking skin. This hydrating serum is fo
Celimax Noni Ampoule Calming + Radiance Versus Isntree Ultra-Low Molecular Hyaluronic Acid Serum
This calming ampoule is formulated around Morinda Citrifolia Fruit Extract and Allantoin to calm redness and brighten dull-looking skin.
This hydrating serum is formulated around Panthenol and Hydrolyzed Hyaluronic Acid to hydrate skin and strengthen the skin barrier.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Butylene Glycol
Propanediol
Glycerin
1,2-Hexanediol
Morinda Citrifolia Fruit Extract 0.7%
Sodium Polyacryloyldimethyl Taurate
Diethoxyethyl Succinate
Allantoin
Octyldodeceth-16
Dipropylene Glycol
Melia Azadirachta Leaf Extract
Sodium Hyaluronate
Ethylhexylglycerin
Adenosine
Disodium EDTA
Panthenol
Glyceryl Polymethacrylate
Melia Azadirachta Flower Extract
Morinda Citrifolia Seed Oil
Hydrogenated Lecithin
Theobroma Cacao Seed Extract
Rosmarinus Officinalis Leaf Oil
Dextrin
Cetearyl Olivate
Sorbitan Olivate
Sucrose Palmitate
Citrus Reticulata Peel Extract
Olea Europaea Fruit Oil
Macadamia Integrifolia Seed Oil
Vitis Vinifera Seed Oil
Simmondsia Chinensis Seed Oil
Soluble Collagen
Tocopherol
Water, Butylene Glycol, Propanediol, Glycerin, 1,2-Hexanediol, Morinda Citrifolia Fruit Extract 0.7%, Sodium Polyacryloyldimethyl Taurate, Diethoxyethyl Succinate, Allantoin, Octyldodeceth-16, Dipropylene Glycol, Melia Azadirachta Leaf Extract, Sodium Hyaluronate, Ethylhexylglycerin, Adenosine, Disodium EDTA, Panthenol, Glyceryl Polymethacrylate, Melia Azadirachta Flower Extract, Morinda Citrifolia Seed Oil, Hydrogenated Lecithin, Theobroma Cacao Seed Extract, Rosmarinus Officinalis Leaf Oil, Dextrin, Cetearyl Olivate, Sorbitan Olivate, Sucrose Palmitate, Citrus Reticulata Peel Extract, Olea Europaea Fruit Oil, Macadamia Integrifolia Seed Oil, Vitis Vinifera Seed Oil, Simmondsia Chinensis Seed Oil, Soluble Collagen, Tocopherol
Sea Water
Methylpropanediol
Betaine
Pentylene Glycol
Carbomer
Caprylyl Glycol
Tromethamine
Xanthan Gum
Malachite Extract
Hydrolyzed Hyaluronic Acid
Glyceryl Acrylate/Acrylic Acid Copolymer
Glyceryl Glucoside
Potassium Hyaluronate
Hyaluronic Acid
Hydrolyzed Sodium Hyaluronate
Sodium Acetylated Hyaluronate
Hydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Crosspolymer
Dimethylsilanol Hyaluronate
Hydrolyzed Calcium Hyaluronate
Sodium Sulfated Hyaluronate
Madecassoside
Beta-Glucan
Sodium Stearoyl Hyaluronate
Sodium Oleoyl Hyaluronate
Sea Water, Water, Methylpropanediol, Glycerin, Butylene Glycol, 1,2-Hexanediol, Betaine, Pentylene Glycol, Carbomer, Caprylyl Glycol, Allantoin, Tromethamine, Ethylhexylglycerin, Xanthan Gum, Panthenol, Malachite Extract, Hydrolyzed Hyaluronic Acid, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Glucoside, Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Dimethylsilanol Hyaluronate, Hydrolyzed Calcium Hyaluronate, Sodium Sulfated Hyaluronate, Madecassoside, Beta-Glucan, Sodium Stearoyl Hyaluronate, Sodium Oleoyl Hyaluronate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!