Skin science article
CeraVe Daily Moisturizing Lotion for Normal to Dry Skin Versus Lancôme Rénergie H.P.N. 300-Peptide Cream
CeraVe Daily Moisturizing Lotion for Normal to Dry Skin Versus Lancôme Rénergie H.P.N. 300-Peptide Cream This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin. This anti-aging moisturiz
CeraVe Daily Moisturizing Lotion for Normal to Dry Skin Versus Lancôme Rénergie H.P.N. 300-Peptide Cream
This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin.
This anti-aging moisturizer is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Caprylic/Capric Triglyceride
Cetearyl Alcohol
Cetyl Alcohol
Potassium Phosphate
Ceramide NP
Ceramide AP
Ceramide EOP
Carbomer
Dimethicone
Ceteareth-20
Behentrimonium Methosulfate
Methylparaben
Sodium Lauroyl Lactylate
Cholesterol
Disodium EDTA
Dipotassium Phosphate
Propylparaben
Hydrolyzed Hyaluronic Acid
Phytosphingosine
Xanthan Gum
Polysorbate 20
Polyglyceryl-3 Diisostearate
Water, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetyl Alcohol, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Dimethicone, Ceteareth-20, Behentrimonium Methosulfate, Methylparaben, Sodium Lauroyl Lactylate, Cholesterol, Disodium EDTA, Dipotassium Phosphate, Propylparaben, Hydrolyzed Hyaluronic Acid, Phytosphingosine, Xanthan Gum, Polysorbate 20, Polyglyceryl-3 Diisostearate
Theobroma Grandiflorum Seed Butter
Alcohol Denat.
Cetearyl Isononanoate
Niacinamide
Glyceryl Stearate
PEG-100 Stearate
Isopropyl Palmitate
Octyldodecanol
Cyclodextrin
Hydrolyzed Lupine Protein
Pisum Sativum Extract
Adenosine
Capryloyl Salicylic Acid
Hydrolyzed Linseed Extract
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Trisodium Ethylenediamine Disuccinate
Tocopheryl Acetate
Cera Alba
Orbignya Oleifera Seed Oil
Simmondsia Chinensis Butter
Cetearyl Glucoside
Citric Acid
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Polysorbate 60
Potassium Cetyl Phosphate
Sorbitan Isostearate
Tocopherol
Dimethicone/Polyglycerin-3 Crosspolymer
Benzyl Alcohol
Geraniol
Limonene
Chlorphenesin
Dipropylene Glycol
Phenoxyethanol
Sodium Benzoate
Parfum
Water, Glycerin, Dimethicone, Cetearyl Alcohol, Theobroma Grandiflorum Seed Butter, Alcohol Denat., Cetearyl Isononanoate, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Isopropyl Palmitate, Octyldodecanol, Cyclodextrin, Hydrolyzed Lupine Protein, Pisum Sativum Extract, Adenosine, Capryloyl Salicylic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Linseed Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Trisodium Ethylenediamine Disuccinate, Tocopheryl Acetate, Cera Alba, Orbignya Oleifera Seed Oil, Simmondsia Chinensis Butter, Cetearyl Glucoside, Citric Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Potassium Cetyl Phosphate, Sorbitan Isostearate, Tocopherol, Dimethicone/Polyglycerin-3 Crosspolymer, Benzyl Alcohol, Geraniol, Limonene, Chlorphenesin, Dipropylene Glycol, Phenoxyethanol, Sodium Benzoate, Parfum
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!