Skin science article
CeraVe Hydrating Hyaluronic Acid Serum Versus Advanced Clinicals Vitamin C Anti Aging Serum
CeraVe Hydrating Hyaluronic Acid Serum Versus Advanced Clinicals Vitamin C Anti Aging Serum This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier. This anti-aging serum is formulated around
CeraVe Hydrating Hyaluronic Acid Serum Versus Advanced Clinicals Vitamin C Anti Aging Serum
This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier.
This anti-aging serum is formulated around Aminopropyl Ascorbyl Phosphate and Ferulic Acid to soften the look of wrinkles and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Cetearyl Ethylhexanoate
Dimethicone
Ammonium Polyacryloyldimethyl Taurate
Sodium Hyaluronate
Panthenol
Ceramide NP
Ceramide AP
Ceramide EOP
Carbomer
Cetearyl Alcohol
Behentrimonium Methosulfate
Sodium Hydroxide
Sodium Lauroyl Lactylate
Cholesterol
Phenoxyethanol
Disodium EDTA
Isopropyl Myristate
Caprylyl Glycol
Citric Acid
Xanthan Gum
Phytosphingosine
Ethylhexylglycerin
Water, Glycerin, Cetearyl Ethylhexanoate, Dimethicone, Ammonium Polyacryloyldimethyl Taurate, Sodium Hyaluronate, Panthenol, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Cetearyl Alcohol, Behentrimonium Methosulfate, Sodium Hydroxide, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Disodium EDTA, Isopropyl Myristate, Caprylyl Glycol, Citric Acid, Xanthan Gum, Phytosphingosine, Ethylhexylglycerin
PEG-12 Dimethicone
Aminopropyl Ascorbyl Phosphate
Ferulic Acid
Lactic Acid
Glycolic Acid
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Aloe Barbadensis Leaf Juice Powder
Tocopherol
Helianthus Annuus Extract
Oryza Sativa Bran Extract
Rosmarinus Officinalis Leaf Extract
Butylene Glycol
Hexylene Glycol
Tetrasodium Glutamate Diacetate
Parfum
Vanillin
Malonic Acid
Sodium Lactate
Polysorbate 20
Limonene
Linalool
Citronellol
Water, PEG-12 Dimethicone, Aminopropyl Ascorbyl Phosphate, Ferulic Acid, Lactic Acid, Glycolic Acid, Glycerin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Aloe Barbadensis Leaf Juice Powder, Tocopherol, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Rosmarinus Officinalis Leaf Extract, Butylene Glycol, Xanthan Gum, Phenoxyethanol, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Tetrasodium Glutamate Diacetate, Parfum, Sodium Hydroxide, Vanillin, Malonic Acid, Carbomer, Sodium Lactate, Polysorbate 20, Limonene, Linalool, Citronellol
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.