Skin science article
CeraVe Hydrating Hyaluronic Acid Serum Versus Face Facts Ceramide Repairing Serum Cream
CeraVe Hydrating Hyaluronic Acid Serum Versus Face Facts Ceramide Repairing Serum Cream This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier. This barrier-repair serum is formulated around
CeraVe Hydrating Hyaluronic Acid Serum Versus Face Facts Ceramide Repairing Serum Cream
This hydrating serum is formulated around Sodium Hyaluronate and Ceramide NP to hydrate skin and strengthen the skin barrier.
This barrier-repair serum is formulated around Avena Sativa Kernel Extract and Ceramide NP to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Cetearyl Ethylhexanoate
Dimethicone
Ammonium Polyacryloyldimethyl Taurate
Sodium Hyaluronate
Panthenol
Ceramide NP
Ceramide AP
Ceramide EOP
Carbomer
Cetearyl Alcohol
Behentrimonium Methosulfate
Sodium Hydroxide
Sodium Lauroyl Lactylate
Cholesterol
Phenoxyethanol
Disodium EDTA
Isopropyl Myristate
Caprylyl Glycol
Citric Acid
Xanthan Gum
Phytosphingosine
Ethylhexylglycerin
Water, Glycerin, Cetearyl Ethylhexanoate, Dimethicone, Ammonium Polyacryloyldimethyl Taurate, Sodium Hyaluronate, Panthenol, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Cetearyl Alcohol, Behentrimonium Methosulfate, Sodium Hydroxide, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Disodium EDTA, Isopropyl Myristate, Caprylyl Glycol, Citric Acid, Xanthan Gum, Phytosphingosine, Ethylhexylglycerin
Glyceryl Stearate
Butylene Glycol
Erythritol
Fructooligosaccharides
Avena Sativa Kernel Extract
Ceramide Ns
Ceramide Ng
Ceramide As
Tocopherol
C14-22 Alcohols
PEG-100 Stearate
Sodium Polyacryloyldimethyl Taurate
Caprylyl Methicone
Sodium Benzoate
C12-20 Alkyl Glucoside
C30-45 Alkyl Cetearyl Dimethicone Crosspolymer
Isohexadecane
PEG-7 Glyceryl Cocoate
1,2-Hexanediol
Hydrogenated Lecithin
Propylene Glycol
Castor Oil Hydrogenated Ethoxylated
Water, Glyceryl Stearate, Butylene Glycol, Erythritol, Fructooligosaccharides, Avena Sativa Kernel Extract, Ceramide NP, Ceramide Ns, Ceramide Ng, Ceramide As, Ceramide EOP, Ceramide AP, Tocopherol, Sodium Hyaluronate, Glycerin, C14-22 Alcohols, PEG-100 Stearate, Sodium Polyacryloyldimethyl Taurate, Caprylyl Methicone, Sodium Benzoate, C12-20 Alkyl Glucoside, C30-45 Alkyl Cetearyl Dimethicone Crosspolymer, Isohexadecane, PEG-7 Glyceryl Cocoate, Phenoxyethanol, 1,2-Hexanediol, Hydrogenated Lecithin, Propylene Glycol, Castor Oil Hydrogenated Ethoxylated, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
Ceramide EOP is formally known as Ceramide 1.
It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).
Low levels of Ceramide EOP have been found in people with eczema and psoriasis.
Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.
In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.
You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!