Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

CeraVe Moisturising Cream Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol

CeraVe Moisturising Cream Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is

CeraVe Moisturising Cream Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol

This barrier-repair moisturizer is formulated around Ceramide NP and Ceramide AP to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Retinol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Cetearyl Alcohol

Caprylic/Capric Triglyceride

Cetyl Alcohol

Ceteareth-20

Petrolatum

Potassium Phosphate

Ceramide NP

Ceramide AP

Ceramide EOP

Carbomer

Dimethicone

Behentrimonium Methosulfate

Sodium Lauroyl Lactylate

Sodium Hyaluronate

Cholesterol

Phenoxyethanol

Disodium EDTA

Dipotassium Phosphate

Tocopherol

Phytosphingosine

Xanthan Gum

Ethylhexylglycerin

Water, Glycerin, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Cetyl Alcohol, Ceteareth-20, Petrolatum, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Dimethicone, Behentrimonium Methosulfate, Sodium Lauroyl Lactylate, Sodium Hyaluronate, Cholesterol, Phenoxyethanol, Disodium EDTA, Dipotassium Phosphate, Tocopherol, Phytosphingosine, Xanthan Gum, Ethylhexylglycerin

Dicaprylyl Carbonate

Ethylhexyl Stearate

Cocoglycerides

Butyrospermum Parkii Butter

Squalane

Sodium Polyacrylate

Lecithin

Adenosine

Palmitoyl Tripeptide-1

Retinol

Punica Granatum Extract

Camellia Oleifera Leaf Extract

Glycyrrhiza Glabra Root Extract

Tetrahydrodiferuloylmethane

Tetrahydrodemethoxydiferuloylmethane

Tetrahydrobisdemethoxydiferuloylmethane

Tocopheryl Acetate

Chamomilla Recutita Flower Extract

Glycine Soja Seed Extract

Glycine Soja Oil

Butylene Glycol

Propylene Glycol

Glyceryl Polymethacrylate

Water, Dicaprylyl Carbonate, Glycerin, Ethylhexyl Stearate, Cocoglycerides, Butyrospermum Parkii Butter, Squalane, Sodium Polyacrylate, Lecithin, Adenosine, Palmitoyl Tripeptide-1, Ceramide NP, Retinol, Punica Granatum Extract, Camellia Oleifera Leaf Extract, Glycyrrhiza Glabra Root Extract, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Tocopheryl Acetate, Chamomilla Recutita Flower Extract, Glycine Soja Seed Extract, Glycine Soja Oil, Butylene Glycol, Propylene Glycol, Glyceryl Polymethacrylate, Xanthan Gum, Phenoxyethanol

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Water
  2. 02Butylene Glycol
  3. 03Polysorbate 20
  4. 04Cetyl Alcohol
  5. 05Salicylic Acid
  6. 06Ammonium Acryloyldimethyltaurate/Vp Copolymer
  7. 07Cyclopentasiloxane
  8. 08Sorbitan Stearate
  9. 09Camellia Sinensis Leaf Extract
  10. 10Lauric Acid
  11. 11Allantoin
  12. 12Glycerin
  13. 13Glycyrrhiza Glabra Root Extract
  14. 14Avena Sativa Kernel Extract
  15. 15Epilobium Angustifolium Extract
  16. 16Dimethicone
  17. 17Xanthan Gum
  18. 18Magnesium Aluminum Silicate
  19. 19PEG-40 Hydrogenated Castor Oil
  20. 20Sodium Hydroxide
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side