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Skin science article

CeraVe Skin Renewing Eye Cream Versus The INKEY List Caffeine Eye Cream

CeraVe Skin Renewing Eye Cream Versus The INKEY List Caffeine Eye Cream This barrier-repair eye moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. This anti-aging eye moisturizer is form

CeraVe Skin Renewing Eye Cream Versus The INKEY List Caffeine Eye Cream

This barrier-repair eye moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Caffeine and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Niacinamide

Cetearyl Alcohol

Cetearyl Ethylhexanoate

Caprylic/Capric Triglyceride

Dimethicone

Petrolatum

Polyacrylate Crosspolymer-6

Hydrogenated Lecithin

Ceramide NP

Ceramide AP

Ceramide EOP

Carbomer

Behentrimonium Methosulfate

Triethyl Citrate

Caffeine

Sodium Hyaluronate

Sodium Lauroyl Lactylate

Sodium Lactate

Cholesterol

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Phenoxyethanol

Isopropyl Myristate

Caprylyl Glycol

Trisodium Ethylenediamine Disuccinate

Phytosphingosine

Xanthan Gum

Butylene Glycol

Polysorbate 20

Benzoic Acid

Water, Propanediol, Glycerin, Niacinamide, Cetearyl Alcohol, Cetearyl Ethylhexanoate, Caprylic/Capric Triglyceride, Dimethicone, Petrolatum, Polyacrylate Crosspolymer-6, Hydrogenated Lecithin, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Behentrimonium Methosulfate, Triethyl Citrate, Caffeine, Sodium Hyaluronate, Sodium Lauroyl Lactylate, Sodium Lactate, Cholesterol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Phenoxyethanol, Isopropyl Myristate, Caprylyl Glycol, Trisodium Ethylenediamine Disuccinate, Phytosphingosine, Xanthan Gum, Butylene Glycol, Polysorbate 20, Benzoic Acid

Dicaprylyl Carbonate

Polyglyceryl-6 Distearate

Cetyl Alcohol

Glyceryl Behenate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Jojoba Esters

Albizia Julibrissin Bark Extract

Squalane

Polyglyceryl-3 Beeswax

Phospholipids

Ethylhexylglycerin

Glycine Soja Oil

Polysorbate 60

Sodium Phytate

Glycolipids

Sorbitan Isostearate

Citric Acid

Glycine Soja Sterols

Leuconostoc/Radish Root Ferment Filtrate

Hyaluronic Acid

Sodium Benzoate

Tocopherol

Darutoside

Water, Glycerin, Dicaprylyl Carbonate, Propanediol, Polyglyceryl-6 Distearate, Cetyl Alcohol, Glyceryl Behenate, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Jojoba Esters, Albizia Julibrissin Bark Extract, Squalane, Caffeine, Polyglyceryl-3 Beeswax, Phospholipids, Ethylhexylglycerin, Xanthan Gum, Glycine Soja Oil, Polysorbate 60, Sodium Phytate, Glycolipids, Sorbitan Isostearate, Butylene Glycol, Citric Acid, Glycine Soja Sterols, Leuconostoc/Radish Root Ferment Filtrate, Hyaluronic Acid, Sodium Benzoate, Tocopherol, Carbomer, Darutoside, Sodium Lactate, Polysorbate 20, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.

This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.

High percentages of Sodium Lactate can have an exfoliating effect.

Fun fact: Sodium Lactate is produced from fermented sugar.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Side-by-side

  1. 01Aloe Barbadensis Leaf Juice
  2. 02Rosa Centifolia Flower Water
  3. 03Rosa Canina Seed Oil
  4. 04Coffea Arabica Seed Extract
  5. 05Camellia Sinensis Leaf Extract
  6. 06Tocopherol
  7. 07Sodium Ascorbate
  8. 08Rosmarinus Officinalis Leaf
  9. 09Origanum Vulgare Leaf
  10. 10Thymus Vulgaris Flower/Leaf Oil
  11. 11Vanilla Planifolia Fruit
  12. 12Euphorbia Cerifera Cera
  13. 13Aloe Barbadensis Leaf Juice, Rosa Centifolia Flower Water, Rosa Canina Seed Oil, Coffea Arabica Seed Extract, Camellia Sinensis Leaf Extract, Tocopherol, Sodium Ascorbate, Rosmarinus Officinalis Leaf, Origanum Vulgare Leaf, Thymus Vulgaris Flower/Le…
  14. 14Water
  15. 15Dimethicone
  16. 16Propylene Glycol
  17. 17Dipropylene Glycol
  18. 18Niacinamide
  19. 19Alcohol Denat.
  20. 20Glycerin
Source · skinsort.com
02

Product index

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Anai Rui Caffeine Eye Cream Ingredients in Anai Rui Caffeine Eye Cream explained: benefits, concerns, and detailed analysis of 35 ingredients including Water, Caffeine, and Retinol A eye mo…

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03

Comparison edit

Read side by side