Skin science article
Cetaphil Daily Oil-Free Hydrating Lotion Versus Paula's Choice Clear Oil-Free Moisturizer
Cetaphil Daily Oil-Free Hydrating Lotion Versus Paula's Choice Clear Oil-Free Moisturizer This moisturizer is formulated around Hydrolyzed Hyaluronic Acid to hydrate skin. This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to stre
Cetaphil Daily Oil-Free Hydrating Lotion Versus Paula's Choice Clear Oil-Free Moisturizer
This moisturizer is formulated around Hydrolyzed Hyaluronic Acid to hydrate skin.
This barrier-repair moisturizer is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and calm redness.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dicaprylyl Carbonate
Hydroxyethyl Urea
Cyclopentasiloxane
Glycerin
Glyceryl Stearate
PEG-100 Stearate
Hydrolyzed Hyaluronic Acid
Sodium Hydroxide
Homarine Hcl
Sodium PCA
Cetyl Alcohol
Caprylyl Glycol
Phenoxyethanol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Erythritol
Water, Dicaprylyl Carbonate, Hydroxyethyl Urea, Cyclopentasiloxane, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Hydrolyzed Hyaluronic Acid, Sodium Hydroxide, Homarine Hcl, Sodium PCA, Cetyl Alcohol, Caprylyl Glycol, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Erythritol
Ethyl Macadamiate
Cetearyl Alcohol
Propanediol
Triethylhexanoin
Sodium Acrylates Copolymer
Glycyrrhiza Glabra Root
Hydrolyzed Pumpkin Seedcake
Vaccinium Angustifolium Fruit Extract
Euterpe Oleracea Fruit Extract
Prunus Serotina Fruit Extract
Niacinamide
Tripeptide-29
Ceramide NP
Ceramide AP
Ceramide EOP
Sodium Hyaluronate
Phytosphingosine
Cholesterol
Panthenol
Adenosine
Lecithin
Arginine
Sodium Lauroyl Lactylate
Sodium Gluconate
Citric Acid
Isohexadecane
Xanthan Gum
Carbomer
Ethylhexylglycerin
Water, Ethyl Macadamiate, Glycerin, Cetearyl Alcohol, Propanediol, Triethylhexanoin, Sodium Acrylates Copolymer, Glyceryl Stearate, PEG-100 Stearate, Glycyrrhiza Glabra Root, Hydrolyzed Pumpkin Seedcake, Vaccinium Angustifolium Fruit Extract, Euterpe Oleracea Fruit Extract, Prunus Serotina Fruit Extract, Niacinamide, Tripeptide-29, Ceramide NP, Ceramide AP, Ceramide EOP, Sodium Hyaluronate, Phytosphingosine, Cholesterol, Panthenol, Sodium PCA, Adenosine, Lecithin, Arginine, Sodium Lauroyl Lactylate, Sodium Gluconate, Citric Acid, Isohexadecane, Xanthan Gum, Carbomer, Phenoxyethanol, Ethylhexylglycerin
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium PCA (the salt of PCA) is one of the most well-established humectants in skincare.
Why is it so special? Your skin already makes it naturally; it's a natural component of your skin's Natural Moisturizing Factor (NMF), or the mix of water-binding compounds inside your skin cells that keeps things soft and hydrated.
As a cosmetic ingredient, it grabs water and holds it in the upper layers of skin to smooth roughness and ease dehydration.
There's some clinical support for the NMF approach with a study showing that a cream built to mimic the skin's NMF significantly boosted hydration.
Safety-wise, this ingredient non-irritating, non-comedogenic, and non-phototoxic in testing, with minimal skin absorption.
It also works really well with other hydrators like glycerin or hyaluronic acid, and typical usage is somewhere between 0.2-4%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!