Skin science article
Cetaphil Deep Hydration Refreshing Eye Serum Versus CeraVe Skin Renewing Vitamin C Eye Cream
Cetaphil Deep Hydration Refreshing Eye Serum Versus CeraVe Skin Renewing Vitamin C Eye Cream This calming eye moisturizer is formulated around 4-T-Butylcyclohexanol and Hydrolyzed Hyaluronic Acid to calm redness and hydrate skin. This anti-aging eye moisturize
Cetaphil Deep Hydration Refreshing Eye Serum Versus CeraVe Skin Renewing Vitamin C Eye Cream
This calming eye moisturizer is formulated around 4-T-Butylcyclohexanol and Hydrolyzed Hyaluronic Acid to calm redness and hydrate skin.
This anti-aging eye moisturizer is formulated around Ascorbic Acid and Ceramide NP to soften the look of wrinkles and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Dicaprylyl Carbonate
Glycerin
1,2-Hexanediol
Polyglyceryl-6 Distearate
Distarch Phosphate
4-T-Butylcyclohexanol
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Anhydroxylitol
Bisabolol
Caprylyl/Capryl Glucoside
Cetyl Alcohol
Citric Acid
Dunaliella Salina Extract
Ethylhexylglycerin
Globularia Alypum Leaf Extract
Hydrolyzed Hyaluronic Acid
Jojoba Esters
Palmitoyl Tripeptide-5
Panthenol
Pantolactone
Pentylene Glycol
Phenoxyethanol
Polyglyceryl-3 Beeswax
Polyisobutene
Potassium Sorbate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Sodium Benzoate
Sodium Hyaluronate
Sodium Hydroxide
Sodium PCA
Sorbitan Oleate
Tocopherol
Xylitol
Xylitylglucoside
Water, Dicaprylyl Carbonate, Glycerin, 1,2-Hexanediol, Polyglyceryl-6 Distearate, Distarch Phosphate, 4-T-Butylcyclohexanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Anhydroxylitol, Bisabolol, Caprylyl/Capryl Glucoside, Cetyl Alcohol, Citric Acid, Dunaliella Salina Extract, Ethylhexylglycerin, Globularia Alypum Leaf Extract, Hydrolyzed Hyaluronic Acid, Jojoba Esters, Palmitoyl Tripeptide-5, Panthenol, Pantolactone, Pentylene Glycol, Phenoxyethanol, Polyglyceryl-3 Beeswax, Polyisobutene, Potassium Sorbate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Benzoate, Sodium Hyaluronate, Sodium Hydroxide, Sodium PCA, Sorbitan Oleate, Tocopherol, Xylitol, Xylitylglucoside
Ascorbic Acid
Propanediol
Dimethicone
Caprylic/Capric Triglyceride
Cetearyl Alcohol
Glyceryl Isostearate
Glyceryl Stearate
PEG-100 Stearate
Dipotassium Glycyrrhizate
Hydrogenated Jojoba Oil
Ceramide NP
Ceramide AP
Ceramide EOP
Carbomer
Copernicia Cerifera Cera
Cetearyl Glucoside
Behentrimonium Methosulfate
Triethyl Citrate
Caffeine
Silica
Sodium Lauroyl Lactylate
Cholesterol
Hydrogenated Lecithin
Hydroxyacetophenone
Caprylyl Glycol
Trisodium Ethylenediamine Disuccinate
Xanthan Gum
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Phytosphingosine
Polyacrylate Crosspolymer-6
Benzoic Acid
Water, Glycerin, Ascorbic Acid, Propanediol, Dimethicone, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Glyceryl Isostearate, Sodium Hydroxide, Glyceryl Stearate, PEG-100 Stearate, Panthenol, Dipotassium Glycyrrhizate, Hydrogenated Jojoba Oil, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Copernicia Cerifera Cera, Cetearyl Glucoside, Behentrimonium Methosulfate, Triethyl Citrate, Caffeine, Silica, Sodium Hyaluronate, Sodium Lauroyl Lactylate, Cholesterol, Phenoxyethanol, Tocopherol, Hydrogenated Lecithin, Hydroxyacetophenone, Citric Acid, Caprylyl Glycol, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Phytosphingosine, Polyacrylate Crosspolymer-6, Benzoic Acid
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!