Skin science article
Cetaphil Optimal Hydration Skin Replenishing Water Gel Versus Beauty of Joseon Red Bean Water Gel
Cetaphil Optimal Hydration Skin Replenishing Water Gel Versus Beauty of Joseon Red Bean Water Gel This barrier-repair moisturizer is formulated around Panthenol and Niacinamide to strengthen the skin barrier and hydrate skin. This calming moisturizer is formul
Cetaphil Optimal Hydration Skin Replenishing Water Gel Versus Beauty of Joseon Red Bean Water Gel
This barrier-repair moisturizer is formulated around Panthenol and Niacinamide to strengthen the skin barrier and hydrate skin.
This calming moisturizer is formulated around Panthenol and Allantoin to calm redness and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dimethicone
Propanediol
Panthenol
Niacinamide
Octyldodecanol
Sodium Polyacryloyldimethyl Taurate
Hydrolyzed Hyaluronic Acid
Sodium Hyaluronate
Polyglutamic Acid
Allantoin
Xylitylglucoside
Anhydroxylitol
Distarch Phosphate
Hydroxyacetophenone
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Caprylyl Glycol
1,2-Hexanediol
Trehalose
Urea
Xylitol
Xanthan Gum
Pentylene Glycol
Serine
Sodium Hydroxide
Pantolactone
Algin
Disodium Phosphate
Glyceryl Polyacrylate
Pullulan
Globularia Alypum Leaf Extract
Citric Acid
Potassium Phosphate
Water, Glycerin, Dimethicone, Propanediol, Panthenol, Niacinamide, Octyldodecanol, Sodium Polyacryloyldimethyl Taurate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Polyglutamic Acid, Allantoin, Xylitylglucoside, Anhydroxylitol, Distarch Phosphate, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, 1,2-Hexanediol, Trehalose, Urea, Xylitol, Xanthan Gum, Pentylene Glycol, Serine, Sodium Hydroxide, Pantolactone, Algin, Disodium Phosphate, Glyceryl Polyacrylate, Pullulan, Globularia Alypum Leaf Extract, Citric Acid, Potassium Phosphate
Butylene Glycol
Methyl Trimethicone
Phaseolus Angularis Seed Extract
Tromethamine
Glyceryl Glucoside
C12-14 Alketh-12
Maltodextrin
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Dimethicone/Vinyl Dimethicone Crosspolymer
Dimethicone Crosspolymer
Ethylhexylglycerin
Betaine
Dipotassium Glycyrrhizate
Polyquaternium-51
Disodium EDTA
Glyceryl Acrylate/Acrylic Acid Copolymer
Dioscorea Japonica Root Extract
Glucose
Sodium Citrate
Beta-Glucan
Hydrolyzed Corn Starch
Sucrose
Magnesium Ascorbyl Phosphate
Helianthus Annuus Seed Oil
Tocopherol
Cyanocobalamin
Glycine
Glutamic Acid
Aspartic Acid
Leucine
Acetyl Hexapeptide-8
Alanine
Lysine
Arginine
Tyrosine
Phenylalanine
Proline
Threonine
Valine
Isoleucine
Histidine
Cysteine
Methionine
Phosphoric Acid
Ascorbic Acid
Sh-Oligopeptide-1
Sh-Oligopeptide-2
Sh-Polypeptide-1
Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Methyl Trimethicone, Phaseolus Angularis Seed Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Glucoside, C12-14 Alketh-12, Maltodextrin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone Crosspolymer, Ethylhexylglycerin, Betaine, Panthenol, Allantoin, Dipotassium Glycyrrhizate, Polyquaternium-51, Xanthan Gum, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Dioscorea Japonica Root Extract, Glucose, Sodium Citrate, Beta-Glucan, Hydrolyzed Corn Starch, Citric Acid, Sucrose, Magnesium Ascorbyl Phosphate, Caprylyl Glycol, Helianthus Annuus Seed Oil, Tocopherol, Cyanocobalamin, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Acetyl Hexapeptide-8, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Cysteine, Methionine, Phosphoric Acid, Ascorbic Acid, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.