Peptide Skincare & BeautySkin science and ingredient guides

Skin science article

Charlotte Tilbury Magic Cream Moisturizer Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel

Charlotte Tilbury Magic Cream Moisturizer Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel This anti-aging moisturizer is formulated around Butyrospermum Parkii Butter and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin. Th

Charlotte Tilbury Magic Cream Moisturizer Versus Paula's Choice Skin Balancing Invisible Finish Moisture Gel

This anti-aging moisturizer is formulated around Butyrospermum Parkii Butter and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin.

This pore-care moisturizer is formulated around Niacinamide and Avena Sativa Kernel Extract to refine the look of pores and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

C12-15 Alkyl Benzoate

Glyceryl Stearate Se

Butylene Glycol

Glycerin

Isononyl Isononanoate

Caprylic/Capric Triglyceride

Cetyl Alcohol

Ethylhexyl Palmitate

Cyclopentasiloxane

Dimethicone

Polyester-7

Phenoxyethanol

Neopentyl Glycol Diheptanoate

Hydrogenated Rapeseed Oil

Butyrospermum Parkii Butter

Steareth-21

Avena Sativa Kernel Extract

Carbomer

Dimethiconol

Potassium Cetyl Phosphate

Chlorphenesin

Caprylyl Glycol

Xanthan Gum

Hydrolyzed Viola Tricolor Extract

Allantoin

Aloe Barbadensis Leaf Juice Powder

Disodium EDTA

Tocopheryl Acetate

Camellia Oleifera Seed Oil

Rosa Canina Fruit Oil

Rosa Damascena Extract

Sodium Hydroxide

Helianthus Annuus Seed Oil

Michelia Alba Leaf Oil

Sodium Lactate

PEG-8

Ethylhexylglycerin

Coco-Glucoside

Sodium Hyaluronate

Tocopherol

Ascorbyl Palmitate

Plumeria Rubra Flower Extract

Ascorbic Acid

Citric Acid

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Hydrolyzed Vegetable Protein

Citronellol

Geraniol

Linalool

Water, C12-15 Alkyl Benzoate, Glyceryl Stearate Se, Butylene Glycol, Glycerin, Isononyl Isononanoate, Caprylic/Capric Triglyceride, Cetyl Alcohol, Ethylhexyl Palmitate, Cyclopentasiloxane, Dimethicone, Polyester-7, Phenoxyethanol, Neopentyl Glycol Diheptanoate, Hydrogenated Rapeseed Oil, Butyrospermum Parkii Butter, Steareth-21, Avena Sativa Kernel Extract, Carbomer, Dimethiconol, Potassium Cetyl Phosphate, Chlorphenesin, Caprylyl Glycol, Xanthan Gum, Hydrolyzed Viola Tricolor Extract, Allantoin, Aloe Barbadensis Leaf Juice Powder, Disodium EDTA, Tocopheryl Acetate, Camellia Oleifera Seed Oil, Rosa Canina Fruit Oil, Rosa Damascena Extract, Sodium Hydroxide, Helianthus Annuus Seed Oil, Michelia Alba Leaf Oil, Sodium Lactate, PEG-8, Ethylhexylglycerin, Coco-Glucoside, Sodium Hyaluronate, Tocopherol, Ascorbyl Palmitate, Plumeria Rubra Flower Extract, Ascorbic Acid, Citric Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Vegetable Protein, Citronellol, Geraniol, Linalool

Bis-Phenylpropyl Dimethicone

Niacinamide

Laminaria Saccharina Extract

Camellia Oleifera Leaf Extract

Vitis Vinifera Seed Extract

Triticum Vulgare Germ Oil

Phenyl Trimethicone

Dipotassium Glycyrrhizate

Tetrahexyldecyl Ascorbate

Phospholipids

Superoxide Dismutase

Isohexadecane

Panthenol

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sodium Carbomer

Dimethicone/Vinyl Dimethicone Crosspolymer

Polysorbate 80

Hydroxyethylcellulose

Water, Cyclopentasiloxane, Butylene Glycol, Glycerin, Bis-Phenylpropyl Dimethicone, Niacinamide, Laminaria Saccharina Extract, Avena Sativa Kernel Extract, Camellia Oleifera Leaf Extract, Vitis Vinifera Seed Extract, Triticum Vulgare Germ Oil, Tocopheryl Acetate, Phenyl Trimethicone, Dimethicone, Dipotassium Glycyrrhizate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Phospholipids, Superoxide Dismutase, Isohexadecane, Panthenol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Carbomer, Dimethicone/Vinyl Dimethicone Crosspolymer, Polysorbate 80, Hydroxyethylcellulose, Ethylhexylglycerin, Phenoxyethanol

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too.

This ingredient helps sooth, hydrate, and protect the skin. The starches in colloidal oatmeal are able to bind water, keeping the skin hydrated.

The cellulose and fiber in colloidal oatmeal help reduce inflammation. This can also help the skin feel softer.

Colloidal Oatmeal is also an antioxidant. Antioxidants protect our skin from free-radical damage.

Oatmeal also contains beneficial compounds:

This ingredient is created by mixing grounded oatmeal and a liquid base.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy.

Since D5 is volatile, it does its thing and then evaporates off the skin quickly.

The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics

There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels.

Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5.

The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

The reference edit

Ingredients, questions
& further reading.

Connected source records selected through this article’s public topic index.

01

Formula cabinet

Ingredients & structured notes

Ingredient index

Ingredients Explained

  1. 01These ingredients are found in both products.
  2. 02Ingredients higher up in an ingredient list are typically present in a larger amount.
  3. 03Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
  4. 04Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
  5. 05Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
  6. 06Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
  7. 07Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
  8. 08Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
  9. 09Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
  10. 10Topically, glycerin does several things at once:
  11. 11Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
  12. 12Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
  13. 13This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
  14. 14Just know very high concentrations (>40%) can feel tacky in low humidity.
  15. 15Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
  16. 16Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.
  17. 17It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.
  18. 18As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.
  19. 19Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.
  20. 20This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.
Source · skinsort.com
02

Product index

Related product references

03

Comparison edit

Read side by side